Product image of Lemsip (Paracetamol) supplied by GNH India

Lemsip

Active Ingredient:
Paracetamol
Origin:
EU

Lemsip (Paracetamol)

Paracetamol, the active ingredient in Lemsip, is an analgesic presented as an oral formulation for oral use. It reduces pain and fever and is commonly used in adults and children for temporary relief of mild to moderate symptoms. The product is marketed across the European Union and is available without prescription.

GNH India supplies Lemsip as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Reckitt Benckiser Healthcare (Belgium) Sa/Nv

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Indications & Clinical Uses

  • Paracetamol acts systemically to alleviate discomfort and lower elevated body temperature associated with common acute conditions.
  • Pain: Provides relief from mild to moderate aches such as headache, toothache, or muscular pain.
  • Fever: Reduces elevated body temperature in febrile illnesses.
  • Headache: Alleviates tension‑type or mild migraine‑related head pain.

How It Works

  • Paracetamol exerts its effect by inhibiting the cyclooxygenase (COX) enzymes in the central nervous system, which reduces the synthesis of prostaglandins involved in pain signaling and thermoregulation. This central inhibition leads to analgesic and antipyretic actions without significant peripheral anti‑inflammatory activity.

Side Effects

Paracetamol is generally well tolerated, but adverse reactions can occur.

Common Side Effects

  • Nausea or mild stomach upset.
  • Transient rash or mild skin irritation.
  • Elevated liver enzymes in occasional laboratory tests.
  • Dizziness or light‑headedness.
  • Rare headache exacerbation.

Serious or Rare Side Effects

  • Severe skin reactions such as Stevens‑Johnson syndrome.
  • Acute liver failure, especially with overdose or chronic excessive use.
  • Anaphylactic or severe allergic reactions.
  • Blood disorders like thrombocytopenia.
  • Hepatic necrosis in patients with pre‑existing liver disease.

Precautions & Warnings

  • Before using Lemsip, consider the following safety measures.
  • Avoid excessive alcohol: Combined use may increase liver toxicity risk.
  • Check liver function: Patients with existing liver disease should consult a healthcare professional.
  • Monitor dosage: Do not exceed the recommended total daily amount of paracetamol from all sources.
  • Pregnancy and breastfeeding: Use only under medical advice, as safety data are limited.
  • Allergy awareness: Discontinue use if signs of hypersensitivity appear.
  • Store at ambient temperature: Keep below 25 °C, in the original packaging, protected from moisture and direct sunlight.

Avoid Interactions

Paracetamol can interact with several medicines; awareness helps prevent adverse outcomes.

Major Interactions (Avoid)

  • Alcohol: Increases risk of hepatotoxicity.
  • Warfarin: May enhance anticoagulant effect, requiring closer INR monitoring.
  • Hepatotoxic drugs (e.g., isoniazid, valproate): Combined use can overload liver metabolism.

Moderate Interactions (Monitor Closely)

  • Enzyme inducers (e.g., carbamazepine, phenytoin): May reduce paracetamol efficacy.
  • Certain antivirals (e.g., ritonavir): Can increase plasma levels.
  • High‑dose vitamin C: May affect renal excretion of metabolites.

Frequently Asked Questions

Lemsip contains paracetamol, which is used to provide temporary relief of mild to moderate pain such as headache, toothache, or muscular aches, and to reduce fever associated with common infections or inflammatory conditions. It is an over‑the‑counter option for adults and children when rapid symptom control is needed.

Paracetamol works by inhibiting cyclooxygenase enzymes in the central nervous system, which lowers the production of prostaglandins that mediate pain and regulate body temperature. This central action results in analgesic (pain‑relieving) and antipyretic (fever‑reducing) effects without significant anti‑inflammatory activity at typical doses.

The appropriate dose of Lemsip is determined by the prescribing healthcare professional based on the patient’s age, weight, and overall health status. The prescriber will consider total daily paracetamol intake from all sources to ensure safe and effective use.

Paracetamol is generally considered one of the safer analgesics for use during pregnancy and lactation, but it should only be taken when recommended by a qualified healthcare provider. The prescriber will weigh potential benefits against any risks and advise on the correct dosage if use is deemed appropriate.

To place an order, submit an enquiry on the Lemsip product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, and will request verification of trade or institutional credentials. After confirmation, the team provides pricing, availability, shipping details, and any necessary import documentation.

The primary alternative to paracetamol‑based products like Lemsip is the non‑steroidal anti‑inflammatory drug (NSAID) class, such as ibuprofen. NSAIDs provide both analgesic and anti‑inflammatory effects but carry higher risks of gastrointestinal irritation, renal impairment, and cardiovascular events, whereas paracetamol has a more favorable gastrointestinal profile but lacks strong anti‑inflammatory activity.

Lemsip should be stored at ambient temperature, preferably below 25 °C. Keep the product in its original packaging, protect it from moisture, direct sunlight, and extreme heat. Ensure the container is tightly closed to maintain product stability throughout its shelf life.

Lemsip is intended for oral use. The product is typically dissolved in a cup of hot water according to the instructions on the label, allowing the paracetamol to be absorbed through the gastrointestinal tract for systemic effect. It should be taken with or without food as directed by the prescriber.

The most serious risks include acute liver injury, especially when taken in excess or combined with alcohol, and severe skin reactions such as Stevens‑Johnson syndrome or toxic epidermal necrolysis. Anaphylaxis or other severe allergic responses are also possible, requiring immediate medical attention if symptoms develop.

Individuals with known hypersensitivity to paracetamol or any excipients in Lemsip should avoid it. Patients with severe liver disease, active alcohol dependence, or those taking other hepatotoxic medications should consult a healthcare professional before use. Children under the recommended age or dosage range should not be given the product.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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