Product image of Lenalidomid 123-Acurae Pharma (Lenalidomide) supplied by GNH India

Lenalidomid 123-Acurae Pharma

Active Ingredient:
Lenalidomide
Origin:
EU

Lenalidomid 123-Acurae Pharma (Lenalidomide)

Lenalidomide, the active ingredient in Lenalidomid 123-Acurae Pharma, is an immunomodulatory drug (IMiD) presented as an oral tablet for oral use. It is indicated for the treatment of multiple myeloma, myelodysplastic syndromes with del(5q), and mantle cell lymphoma in appropriate patients.

GNH India supplies Lenalidomid 123-Acurae Pharma as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, oncology centres, pharmacies and clinics worldwide.

Manufacturer / TM Owner

123 Acurae Pharma Gmbh

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Indications & Clinical Uses

Lenalidomide is used in hematologic malignancies and related disorders, acting on abnormal plasma cells and dysplastic marrow clones.

  • Multiple Myeloma: reduces disease progression and improves survival in eligible patients.
  • Myelodysplastic Syndromes with del(5q): corrects ineffective hematopoiesis and decreases transfusion dependence.
  • Mantle Cell Lymphoma: contributes to disease control when combined with other therapies.

How It Works

  • Lenalidomide modulates the immune system by enhancing T‑cell and natural killer cell activity, inhibits angiogenesis, and directly interferes with tumor cell proliferation. It alters cytokine production, down‑regulates pro‑inflammatory factors, and promotes degradation of transcription factors essential for malignant cell survival, resulting in anti‑tumor effects.

Side Effects

Lenalidomide may cause a range of adverse reactions that vary in frequency and severity.

Common Side Effects

  • Neutropenia: reduced neutrophil count increasing infection risk.
  • Thrombocytopenia: lowered platelet levels leading to bleeding tendencies.
  • Fatigue: persistent tiredness affecting daily activities.
  • Nausea: mild to moderate gastrointestinal upset.

Serious or Rare Side Effects

  • Venous thromboembolism: deep vein thrombosis or pulmonary embolism.
  • Secondary primary malignancies: emergence of new cancers.
  • Severe allergic reactions: rash, swelling, or anaphylaxis.

Precautions & Warnings

Before initiating therapy, clinicians should evaluate patient-specific risk factors and monitor relevant parameters.

  • Pregnancy: contraindicated; ensure effective contraception for both patient and partner.
  • Thrombosis risk: assess history and consider prophylactic anticoagulation when appropriate.
  • Hematologic monitoring: perform regular complete blood counts to detect cytopenias.
  • Renal impairment: adjust dosing based on renal function assessment.
  • Store at room temperature: keep in the original container, protect from moisture and light.

Avoid Interactions

Lenalidomide can interact with several drug classes, requiring careful management.

Major Interactions (Avoid)

  • Strong CYP3A4 inducers (e.g., rifampin): may markedly reduce lenalidomide exposure.
  • Concurrent teratogenic agents: increase risk of fetal harm.

Moderate Interactions (Monitor Closely)

  • Antiplatelet agents (e.g., aspirin): monitor for enhanced bleeding.
  • Live vaccines: avoid due to potential reduced immune response.
  • NSAIDs: watch for renal function changes, especially in compromised patients.

Frequently Asked Questions

Lenalidomid 123-Acurae Pharma, containing lenalidomide, is prescribed for multiple myeloma, myelodysplastic syndromes with a deletion of chromosome 5q, and mantle cell lymphoma. These are hematologic cancers where the drug’s immunomodulatory and anti‑angiogenic actions help control disease progression.

Lenalidomide works by enhancing the activity of T‑cells and natural killer cells, suppressing the formation of new blood vessels that feed tumors, and directly inhibiting tumor cell growth. It modifies cytokine production and promotes the degradation of transcription factors that malignant cells rely on, leading to reduced proliferation.

The specific dose of Lenalidomid 123-Acurae Pharma is determined by the prescribing physician based on the patient’s diagnosis, disease stage, renal function, and overall health. Healthcare providers tailor the regimen to achieve optimal therapeutic benefit while minimizing risks.

Lenalidomid 123-Acurae Pharma is classified as pregnancy category X, meaning it is contraindicated in pregnancy due to a high risk of fetal harm. Women of childbearing potential must use effective contraception, and breastfeeding is not recommended while receiving the medication.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Lenalidomide belongs to the immunomodulatory drug class, offering a distinct mechanism compared with proteasome inhibitors or monoclonal antibodies. It is often used in combination regimens to enhance immune response and inhibit angiogenesis, providing an alternative or complementary option to other standard therapies.

Store Lenalidomid 123-Acurae Pharma at room temperature, below 25 °C, in its original packaging. Protect the tablets from moisture, excessive heat, and direct sunlight to maintain product stability throughout its shelf life.

The medication is taken orally, usually once daily, with or without food as directed by the prescriber. Patients should swallow the tablet whole and follow any specific timing or dietary instructions provided by their healthcare professional.

Serious risks include venous thromboembolism, severe neutropenia or thrombocytopenia leading to infection or bleeding, secondary primary malignancies, and profound teratogenic effects. Patients should be monitored closely for these events, and immediate medical attention is required if they occur.

Lenalidomid 123-Acurae Pharma should not be used by pregnant women, individuals with known hypersensitivity to lenalidomide or its excipients, and patients with uncontrolled severe infections. Caution is also advised for those with significant renal impairment or a history of thromboembolic events.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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