Product image of Lenalidomid Glenmark (Lenalidomide) supplied by GNH India

Lenalidomid Glenmark

Active Ingredient:
Lenalidomide
Origin:
EU

Lenalidomid Glenmark (Lenalidomide)

Lenalidomide, the active ingredient in Lenalidomid Glenmark, is an immunomodulatory imide drug (IMiD) presented as an oral tablet for systemic use. It is employed in the treatment of certain blood cancers, notably multiple myeloma and myelodysplastic syndromes, in adult patients.

GNH India supplies Lenalidomid Glenmark as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, oncology centres and pharmacies worldwide.

Manufacturer / TM Owner

Glenmark Pharmaceuticals S.R.O.

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

  • Lenalidomid Glenmark is indicated for hematologic malignancies that respond to immunomodulatory therapy.
  • Multiple Myeloma: improves progression‑free survival and overall response rates in relapsed or refractory disease.
  • Myelodysplastic Syndromes (with del(5q)): reduces transfusion dependence and induces cytogenetic remission.
  • Maintenance Therapy in Multiple Myeloma: prolongs remission after initial response.

How It Works

  • Lenalidomide binds to the cereblon component of the CRL4 E3 ubiquitin ligase complex, directing the transcription factors Ikaros and Aiolos for proteasomal degradation. This results in anti‑angiogenic activity, modulation of cytokine production, enhanced immune‑mediated tumor cell killing, and direct inhibition of malignant cell proliferation.

Side Effects

Lenalidomid Glenmark may cause a range of adverse reactions, which are categorized by frequency and severity.

Common Side Effects

  • Fatigue
  • Neutropenia
  • Thrombocytopenia
  • Diarrhea
  • Constipation
  • Rash

Serious or Rare Side Effects

  • Venous thromboembolism
  • Severe neutropenia or infection risk
  • Severe thrombocytopenia leading to bleeding
  • Secondary primary malignancies
  • Hepatotoxicity
  • Hypersensitivity reactions including Stevens‑Johnson syndrome

Precautions & Warnings

  • Before initiating therapy, clinicians should evaluate patient‑specific risk factors and monitor for known safety concerns.
  • Pregnancy Contraindication: Lenalidomide is teratogenic; avoid use in pregnant women.
  • Thrombotic Risk: Assess and mitigate risk of blood clots, especially with concomitant steroids.
  • Hematologic Monitoring: Perform regular complete blood counts to detect cytopenias.
  • Renal/Hepatic Function: Adjust therapy based on kidney and liver function assessments.
  • Store at room temperature: keep in the original container, protect from moisture and light.

Avoid Interactions

Lenalidomid Glenmark can interact with several drug classes; awareness helps prevent adverse outcomes.

Major Interactions (Avoid)

  • Strong CYP3A4 inhibitors (e.g., ketoconazole) may increase lenalidomide exposure.
  • Anticoagulants (e.g., warfarin) can heighten bleeding risk.
  • Live vaccines: may cause uncontrolled infection.

Moderate Interactions (Monitor Closely)

  • CYP3A4 inducers (e.g., rifampin) may reduce efficacy.
  • Non‑steroidal anti‑inflammatory drugs (NSAIDs) increase gastrointestinal toxicity.
  • Immunosuppressants may augment infection risk.

Frequently Asked Questions

Lenalidomid Glenmark contains lenalidomide, an immunomodulatory agent approved for the treatment of multiple myeloma and myelodysplastic syndromes that carry a del(5q) chromosomal abnormality. It is used in adult patients to improve disease control, reduce transfusion needs, and extend survival when other therapies are insufficient.

Lenalidomide binds to cereblon, a component of the CRL4 E3 ubiquitin ligase complex, leading to the targeted degradation of transcription factors Ikaros and Aiolos. This triggers anti‑angiogenic effects, modulates cytokine release, enhances immune‑mediated tumor cell killing, and directly suppresses malignant cell growth.

The specific dose of Lenalidomid Glenmark is individualized and determined by the prescribing physician based on the patient’s diagnosis, disease stage, renal function, and prior therapies. Clinicians follow approved labeling and clinical guidelines to set the appropriate regimen.

Lenalidomid Glenmark is classified as Pregnancy Category X because it is teratogenic and can cause fetal harm. It should not be used by pregnant women, and effective contraception is required during treatment and for a defined period afterward. Use during breastfeeding is not recommended as the drug may pass into milk.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

Both lenalidomide and thalidomide belong to the immunomodulatory imide drug (IMiD) class, but lenalidomide is more potent, has a shorter half‑life, and generally exhibits a more favorable safety profile, especially regarding peripheral neuropathy. Lenalidomide also demonstrates stronger anti‑angiogenic and immune‑stimulating effects, making it the preferred option for many approved indications.

Store Lenalidomid Glenmark at room temperature, below 25 °C, in the original blister pack or bottle. Keep the product away from moisture, direct sunlight, and excessive heat. Do not use if the packaging is damaged or if the tablets appear discolored.

Lenalidomid Glenmark is taken orally, usually once daily, with or without food, as directed by the prescriber. Swallow the tablet whole with a glass of water; do not crush, split, or chew unless specifically instructed. Adherence to the prescribed schedule is essential for optimal therapeutic effect.

The most serious risks include severe neutropenia or infection, thrombocytopenia leading to bleeding, venous thromboembolism, secondary primary malignancies, and serious hypersensitivity reactions such as Stevens‑Johnson syndrome. Patients should be monitored closely for signs of infection, clotting events, and unusual skin reactions.

Lenalidomid Glenmark is contraindicated in pregnant women, individuals with known hypersensitivity to lenalidomide or any component of the formulation, and patients with uncontrolled active infections. Caution is also advised for those with severe renal impairment, hepatic dysfunction, or a history of thromboembolic disease.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.