Product image of Lenalidomid Sandoz (Lenalidomide) supplied by GNH India

Lenalidomid Sandoz

Active Ingredient:
Lenalidomide
Origin:
EU

Lenalidomid Sandoz (Lenalidomide)

Lenalidomide, the active ingredient in Lenalidomid Sandoz, is an immunomodulatory drug (IMiD) presented as an oral tablet for oral use. It is indicated for the treatment of multiple myeloma, myelodysplastic syndromes with del(5q) and mantle cell lymphoma in adult patients.

GNH India supplies Lenalidomid Sandoz as a licensed, GDP‑compliant international pharmaceutical supplier, ensuring quality and regulatory compliance for hospitals, oncology centres, pharmacies and clinics worldwide. The company leverages a global distribution network to meet demand in both mature and emerging markets.

Manufacturer / TM Owner

Sandoz Gmbh

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Indications & Clinical Uses

Lenalidomide is an immunomodulatory antineoplastic agent used in specific hematologic malignancies and related disorders.

  • Multiple myeloma: improves progression‑free survival, overall response rates and depth of response when combined with dexamethasone or other standard regimens.
  • Myelodysplastic syndromes with del(5q): induces transfusion independence, reduces red‑cell transfusion requirements and can achieve cytogenetic remission in patients harboring the del(5q) abnormality.
  • Mantle cell lymphoma: provides disease control and prolongs remission duration in relapsed or refractory cases, often administered together with rituximab or other targeted therapies.

How It Works

  • Lenalidomide binds to the cereblon component of the CRL4‑E3 ubiquitin ligase complex, altering substrate specificity and promoting ubiquitination of the transcription factors Ikaros (IKZF1) and Aiolos (IKZF3). Their degradation leads to

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

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