Product image of Lenalidomid Teva (Lenalidomide) supplied by GNH India

Lenalidomid Teva

Active Ingredient:
Lenalidomide
Origin:
EU

Lenalidomid Teva (Lenalidomide)

Lenalidomide, the active ingredient in Lenalidomid Teva, is an immunomodulatory drug (IMiD) presented as an oral formulation for oral use. It treats multiple myeloma, myelodysplastic syndromes and mantle cell lymphoma in adult patients.

GNH India supplies Lenalidomid Teva as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, oncology centres, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Teva B.V

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Indications & Clinical Uses

  • Lenalidomid Teva is an immunomodulatory agent used in hematologic malignancies.
  • Multiple Myeloma: improves progression‑free survival and disease control in adult patients.
  • Myelodysplastic Syndromes: reduces transfusion dependence and improves blood counts in patients with del(5q) cytogenetic abnormality.
  • Mantle Cell Lymphoma: contributes to disease remission when used in combination therapy for adult patients.

How It Works

  • Lenalidomide binds to cereblon, a component of the CRL4‑CRBN E3 ubiquitin ligase complex, altering substrate specificity. This leads to degradation of transcription factors Ikaros and Aiolos, resulting in modulation of cytokine production, inhibition of angiogenesis, and induction of apoptosis in malignant plasma cells and other tumor cells.

Side Effects

Lenalidomid Teva may cause a range of adverse reactions.

Common Side Effects

  • Fatigue
  • Neutropenia
  • Thrombocytopenia
  • Diarrhea
  • Rash
  • Anemia

Serious or Rare Side Effects

  • Venous thromboembolism
  • Secondary primary malignancies
  • Severe neutropenia with infection risk
  • Hepatic toxicity
  • Tumor lysis syndrome
  • Interstitial lung disease

Precautions & Warnings

  • Use of Lenalidomid Teva requires careful monitoring and patient counseling.
  • Monitor blood counts: perform regular CBC to detect cytopenias.
  • Assess for thrombotic risk: evaluate history of clotting disorders.
  • Avoid use in pregnancy: drug is teratogenic; ensure effective contraception.
  • Adjust dose in renal impairment: follow prescribing guidelines for reduced renal function.
  • Store at ambient temperature: keep below 25°C in original container, protect from moisture.

Avoid Interactions

Lenalidomid Teva can interact with other medicines, affecting safety or efficacy.

Major Interactions (Avoid)

  • Strong CYP3A4 inhibitors: may increase lenalidomide exposure.
  • Anticoagulants: increased risk of bleeding.
  • Live vaccines: risk of infection due to immunosuppression.

Moderate Interactions (Monitor Closely)

  • CYP3A4 inducers: may reduce therapeutic effect.
  • Other myelosuppressive agents: monitor blood counts closely.
  • HIV protease inhibitors: may alter drug metabolism.

Frequently Asked Questions

Lenalidomid Teva contains lenalidomide and is indicated for the treatment of multiple myeloma, myelodysplastic syndromes with del(5q) cytogenetic abnormality, and mantle cell lymphoma in adult patients, typically as part of a prescribed therapeutic regimen.

Lenalidomide binds to the cereblon component of the CRL4‑CRBN E3 ubiquitin ligase, leading to selective degradation of transcription factors that regulate cell survival. This results in immune modulation, inhibition of new blood‑vessel formation, and promotion of programmed cell death in malignant cells.

The specific dose of Lenalidomid Teva is determined by the prescribing clinician based on the patient’s diagnosis, disease stage, renal function, and other individual factors. Only a qualified healthcare professional should set the dosing schedule.

Lenalidomid Teva is classified as teratogenic and is contraindicated in pregnancy. Women of child‑bearing potential must use effective contraception. Safety during breastfeeding has not been established, and breastfeeding is generally not recommended while on therapy.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Lenalidomid Teva belongs to the immunomodulatory drug class, offering a distinct mechanism compared with proteasome inhibitors or monoclonal antibodies. It is often used in combination regimens and may provide benefits in disease control and progression‑free survival, though choice of therapy depends on individual patient factors and physician judgment.

Lenalidomid Teva should be stored at ambient temperature, below 25 °C, in its original packaging. Protect the product from moisture and direct sunlight to maintain stability throughout its shelf life.

Lenalidomid Teva is taken orally, usually as a tablet or capsule, with or without food as directed by the prescriber. Patients should follow the exact schedule and instructions provided by their healthcare professional.

Serious risks include venous thromboembolism, severe neutropenia leading to infection, secondary primary malignancies, hepatic toxicity, and rare pulmonary complications such as interstitial lung disease. Patients should be monitored closely for these events.

Lenalidomid Teva should not be used by individuals with known hypersensitivity to lenalidomide or any excipients, pregnant women, or patients with severe renal impairment unless dose adjustments are made. It is also contraindicated in patients with active uncontrolled infections.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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