Product image of Lenalidomida Tecnigen (Lenalidomide) supplied by GNH India

Lenalidomida Tecnigen

Active Ingredient:
Lenalidomide
Origin:
EU

Lenalidomida Tecnigen (Lenalidomide)

Lenalidomide, the active ingredient in Lenalidomida Tecnigen, is an immunomodulatory drug (IMiD) presented as an oral tablet for systemic use. It is employed in the treatment of certain blood cancers, including multiple myeloma, myelodysplastic syndromes with del(5q) and mantle cell lymphoma, targeting malignant cell growth and immune modulation.

GNH India supplies Lenalidomida Tecnigen as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, oncology centres, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory documentation for import and distribution.

Manufacturer / TM Owner

Tecnimede España Ind. Fca., S.A.

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Lenalidomide is used in hematologic malignancies that involve abnormal plasma or lymphoid cells.

  • Multiple myeloma: reduces disease progression and improves survival in patients with relapsed or refractory disease.
  • Myelodysplastic syndromes with del(5q): induces transfusion independence and cytogenetic remission.
  • Mantle cell lymphoma: contributes to disease control in patients who have received prior therapies.

How It Works

  • Lenalidomide binds to the cereblon component of the CRL4^CRBN E3 ubiquitin ligase complex, altering its substrate specificity. This leads to ubiquitination and proteasomal degradation of transcription factors Ikaros (IKZF1) and Aiolos (IKZF3), resulting in modulation of cytokine production, inhibition of angiogenesis, and induction of apoptosis in malignant plasma and lymphoid cells. The downstream effects also include enhanced natural killer cell activity and reduced tumor‑supporting microenvironment.

Side Effects

Lenalidomide may cause a range of adverse reactions, varying from mild to severe.

Common Side Effects

  • Fatigue
  • Neutropenia
  • Thrombocytopenia
  • Diarrhea
  • Rash
  • Constipation

Serious or Rare Side Effects

  • Venous thromboembolism
  • Secondary primary malignancies
  • Severe neutropenia
  • Severe infections
  • Hepatotoxicity
  • Tumor lysis syndrome

Precautions & Warnings

When prescribing Lenalidomida Tecnigen, clinicians should observe several safety measures to minimize risk.

  • Pregnancy contraindication: drug is teratogenic (Category X) and must not be used during pregnancy.
  • Thrombosis risk: assess patient history and consider prophylactic anticoagulation.
  • Hematologic monitoring: perform regular complete blood counts to detect neutropenia or thrombocytopenia.
  • Renal/hepatic function: adjust dose in patients with impaired clearance.
  • Drug interaction vigilance: avoid concomitant use with strong CYP3A4 inducers.
  • Store at ambient temperature: keep below 25 °C, in original container, protected from moisture and light.

Avoid Interactions

Lenalidomide interacts with several medicines that can alter its efficacy or safety profile.

Major Interactions (Avoid)

  • Strong CYP3A4 inducers (e.g., rifampin, carbamazepine): may reduce plasma concentrations and therapeutic effect.
  • Live vaccines: concurrent use can increase risk of severe infection.
  • Anticoagulants (warfarin): may increase bleeding risk when combined with lenalidomide‑induced thrombocytopenia.

Moderate Interactions (Monitor Closely)

  • Antiplatelet agents (aspirin, clopidogrel): monitor platelet counts and bleeding signs.
  • P‑glycoprotein inhibitors (e.g., verapamil): may increase lenalidomide exposure.
  • Non‑live vaccines: timing should be coordinated with treatment cycles.

Frequently Asked Questions

Lenalidomida Tecnigen, containing lenalidomide, is indicated for the treatment of multiple myeloma, myelodysplastic syndromes with the del(5q) cytogenetic abnormality, and mantle cell lymphoma. These are hematologic cancers where the drug helps control disease progression and improve patient outcomes.

Lenalidomide binds to cereblon, a component of the CRL4‑CRBN E3 ubiquitin ligase complex, changing its substrate specificity. This triggers degradation of transcription factors Ikaros and Aiolos, leading to altered cytokine production, reduced angiogenesis, enhanced immune cell activity, and programmed cell death of malignant plasma and lymphoid cells.

The specific dose of Lenalidomida Tecnigen is determined by the prescribing physician based on the patient’s diagnosis, disease stage, renal and hepatic function, and prior therapies. Dosage regimens are individualized and should follow the prescriber’s instructions and local regulatory guidelines.

Lenalidomida Tecnigen is classified as Pregnancy Category X, indicating it is contraindicated in pregnancy because of a high risk of fetal harm. Women of childbearing potential must use effective contraception, and the drug should not be used while breastfeeding.

To order Lenalidomida Tecnigen, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, and will request trade or institutional credentials before providing pricing, availability, shipping details and any required import documentation.

Both lenalidomide and thalidomide belong to the immunomodulatory drug (IMiD) class, but lenalidomide has a more favorable safety profile, especially regarding peripheral neuropathy. Lenalidomide also shows stronger anti‑angiogenic and anti‑myeloma activity, making it the preferred option for many approved indications.

Lenalidomida Tecnigen should be stored at ambient temperature, preferably below 25 °C. Keep the tablets in the original packaging, protect them from moisture, light and excessive heat to maintain product stability throughout its shelf life.

Lenalidomida Tecnigen is taken orally, usually once daily, with or without food, as directed by the prescriber. Swallow the tablet whole with water and follow the dosing schedule provided in the prescription to ensure optimal therapeutic effect.

Serious risks include venous thromboembolism, severe neutropenia, severe infections, secondary primary malignancies, and hepatotoxicity. Patients should be monitored regularly for signs of blood clots, low blood counts, liver enzyme changes, and any new cancer development.

Lenalidomida Tecnigen should not

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Related Products

Other formulations containing Lenalidomide

A

A
A

A
A

A
A

A

Browse all products →

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Regulatory recognitions

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.

SGS GSDP Certification

GSDP Compliant from SGS

URS ISO 9001

URS ISO 9001 Certification

FDA Maharashtra

Licensed by FDA Maharashtra

IEC License DGFT

IEC License issued by DGFT