Product image of Lenalidomide Eg (Lenalidomide) supplied by GNH India

Lenalidomide Eg

Active Ingredient:
Lenalidomide
Origin:
EU

Lenalidomide Eg (Lenalidomide)

Lenalidomide, the active ingredient in Lenalidomide Eg, is an immunomodulatory drug (IMiD) presented as an oral formulation for oral use. It is employed in the treatment of certain hematologic malignancies, including multiple myeloma, myelodysplastic syndromes, and mantle cell lymphoma, typically in adult patients who have received prior therapies.

GNH India supplies Lenalidomide Eg as a licensed, GDP‑compliant international pharmaceutical supplier, providing the product to hospitals, oncology centres, pharmacies and clinics worldwide, sourced from the European Union market.

Manufacturer / TM Owner

Eg Labo Laboratoires Eurogenerics

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

  • Lenalidomide is an immunomodulatory agent used in the management of specific hematologic cancers.
  • Multiple Myeloma: improves progression‑free survival and overall response rates in patients with relapsed or refractory disease.
  • Myelodysplastic Syndromes: reduces transfusion dependence and delays transformation to acute leukemia in patients with del(5q) cytogenetic abnormality.
  • Mantle Cell Lymphoma: induces tumor regression and extends survival in patients with relapsed or refractory disease.

How It Works

  • Lenalidomide binds to the cereblon component of the CRL4‑E3 ubiquitin ligase complex, altering substrate specificity and promoting ubiquitination and proteasomal degradation of the transcription factors Ikaros (IKZF1) and Aiolos (IKZF3). This modulates cytokine production, enhances T‑cell and NK‑cell mediated immunity, and inhibits angiogenesis, collectively contributing to its antineoplastic activity.

Side Effects

Lenalidomide may cause a range of adverse reactions, varying in frequency and severity.

Common Side Effects

  • Fatigue: persistent tiredness.
  • Diarrhea: loose stools.
  • Nausea: sensation of queasiness.
  • Rash: mild skin eruptions.

Serious or Rare Side Effects

  • Thromboembolic events: deep vein thrombosis or pulmonary embolism.
  • Severe neutropenia: markedly reduced neutrophil count.
  • Hepatotoxicity: elevated liver enzymes or liver injury.

Precautions & Warnings

  • Lenalidomide requires careful monitoring and specific safety measures.
  • Pregnancy: contraindicated; teratogenic risk (Category X).
  • Thrombosis risk: assess and consider prophylactic anticoagulation.
  • Renal impairment: use with caution and monitor renal function.
  • Hepatic dysfunction: monitor liver function tests regularly.
  • Blood counts: perform baseline and periodic CBC to detect cytopenias.
  • Store at ambient temperature: keep below 25 °C, in original container, protect from moisture and light.

Avoid Interactions

Lenalidomide can interact with several medicines, requiring attention to avoid reduced efficacy or increased toxicity.

Major Interactions (Avoid)

  • Strong CYP3A4 inducers (e.g., rifampin, carbamazepine): may reduce lenalidomide exposure.
  • Anticoagulants (e.g., warfarin, DOACs): increased risk of thromboembolic events.
  • Immunosuppressants (e.g., cyclosporine): may enhance hematologic toxicity.

Moderate Interactions (Monitor Closely)

  • P-glycoprotein inhibitors (e.g., verapamil): may increase plasma levels.
  • NSAIDs: additive risk of renal impairment.
  • Live vaccines: may be less effective while on therapy.

Frequently Asked Questions

Lenalidomide Eg is used to treat certain blood‑related cancers, specifically multiple myeloma, myelodysplastic syndromes with a del(5q) abnormality, and mantle cell lymphoma, usually after prior therapies have been tried.

Lenalidomide binds to cereblon, a component of an E3 ubiquitin ligase complex, leading to the degradation of transcription factors Ikaros and Aiolos. This alters cytokine production, boosts immune‑cell activity, and blocks new blood‑vessel formation, together inhibiting cancer cell growth.

The dosage of Lenalidomide Eg is determined by the prescribing clinician based on the specific indication, patient characteristics, and treatment history. Only a qualified healthcare professional should set the dose and schedule.

Lenalidomide is classified as pregnancy category X because it can cause severe birth defects. It is contraindicated in pregnancy and should not be used by nursing mothers, as it may be excreted in breast milk and harm the infant.

To order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Lenalidomide belongs to the immunomodulatory drug class, offering a distinct mechanism from proteasome inhibitors or monoclonal antibodies. It is often combined with dexamethasone or used after other regimens, providing an alternative option that targets the cereblon pathway and can improve response rates in relapsed disease.

Lenalidomide Eg should be stored at ambient temperature, preferably below 25 °C, in its original packaging. Keep the product away from moisture, direct sunlight and heat to maintain stability.

Lenalidomide Eg is taken orally, usually as a tablet or capsule, with or without food as directed by the prescriber. Patients should follow the exact instructions on timing and any required concomitant medications.

The most serious risks include thromboembolic events such as deep‑vein thrombosis or pulmonary embolism, severe neutropenia that can lead to infections, and potential liver injury. Patients should be monitored closely for signs of these complications.

Lenalidomide Eg should not be used by pregnant women, nursing mothers, or individuals with known hypersensitivity to lenalidomide or its excipients. Caution is also advised for patients with severe renal or hepatic impairment, and those at high risk for blood clots.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Related Products

Other formulations containing Lenalidomide

A

A
A

A
A

A
A

A

Browse all products →

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Regulatory recognitions

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.

SGS GSDP Certification

GSDP Compliant from SGS

URS ISO 9001

URS ISO 9001 Certification

FDA Maharashtra

Licensed by FDA Maharashtra

IEC License DGFT

IEC License issued by DGFT