Product image of Lenalidomide Glenmark (Lenalidomide) supplied by GNH India

Lenalidomide Glenmark

Active Ingredient:
Lenalidomide
Origin:
EU

Lenalidomide Glenmark (Lenalidomide)

Lenalidomide, the active ingredient in Lenalidomide Glenmark, is an immunomodulatory agent presented as an oral tablet for oral use. It treats multiple myeloma, myelodysplastic syndromes, and mantle cell lymphoma in adult patients.

GNH India supplies Lenalidomide Glenmark as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, oncology centres and pharmacies worldwide.

Manufacturer / TM Owner

Glenmark Arzneimittel Gmbh

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

  • Lenalidomide is an immunomodulatory agent used in hematologic malignancies.
  • Multiple Myeloma: improves disease control and prolongs progression‑free survival in relapsed or refractory patients.
  • Myelodysplastic Syndromes: reduces transfusion dependence and improves blood counts in patients with del(5q) cytogenetic abnormality.
  • Mantle Cell Lymphoma: contributes to disease control in relapsed or refractory mantle cell lymphoma.

How It Works

  • Lenalidomide binds to the cereblon component of the CRL4 E3 ubiquitin ligase complex, promoting ubiquitination and proteasomal degradation of transcription factors Ikaros and Aiolos. This leads to modulation of cytokine production, inhibition of angiogenesis, and anti‑proliferative effects on malignant plasma cells and other hematologic cancer cells.

Side Effects

Common Side Effects

  • Fatigue or weakness.
  • Nausea, vomiting or loss of appetite.
  • Diarrhoea or constipation.
  • Rash or mild skin irritation.
  • Decreased neutrophil count (neutropenia).
  • Low platelet count (thrombocytopenia).

Serious or Rare Side Effects

  • Thromboembolic events such as deep‑vein thrombosis or pulmonary embolism.
  • Severe neutropenia or infections requiring hospitalization.
  • Secondary primary malignancies.
  • Hepatotoxicity with elevated liver enzymes.
  • Severe skin reactions including Stevens‑Johnson syndrome.
  • Cardiac arrhythmias or heart failure exacerbation.

Precautions & Warnings

  • Lenalidomide requires careful monitoring and specific safety measures.
  • Pregnancy: contraindicated (Category X); avoid use in pregnant women and ensure effective contraception.
  • Thromboembolism risk: assess patient history and consider prophylactic anticoagulation.
  • Hematologic monitoring: perform regular complete blood counts to detect neutropenia or anemia.
  • Renal impairment: use with caution and monitor renal function closely.
  • Drug interactions: review concomitant medications for potential CYP or immunosuppressive effects.
  • Store at ambient temperature: keep below 25°C, protect from moisture and light in the original packaging.

Avoid Interactions

Lenalidomide may interact with several drug classes; monitoring is essential.

Major Interactions (Avoid)

  • Strong CYP3A4 inducers: may reduce lenalidomide exposure.
  • Anticoagulants: increased risk of thrombosis when combined without prophylaxis.
  • Live vaccines: heightened risk of severe infection.

Moderate Interactions (Monitor Closely)

  • Immunosuppressants: may enhance overall immunosuppression.
  • Nephrotoxic agents: monitor renal function closely.
  • Hormonal contraceptives: reduced efficacy; advise alternative contraception methods.

Frequently Asked Questions

Lenalidomide Glenmark is prescribed for adult patients with multiple myeloma, myelodysplastic syndromes that have a del(5q) chromosomal abnormality, and mantle cell lymphoma, particularly in relapsed or refractory disease settings.

Lenalidomide binds to cereblon, a component of the CRL4 E3 ubiquitin ligase complex, leading to the degradation of transcription factors Ikaros and Aiolos. This action modulates immune responses, inhibits new blood‑vessel formation, and reduces proliferation of malignant cells.

The specific dose and schedule of Lenalidomide Glenmark are determined by the prescribing physician based on the patient’s diagnosis, disease stage, renal function, and other clinical factors. Patients should follow the prescriber’s instructions exactly.

Lenalidomide is classified as Pregnancy Category X, meaning it is contraindicated in pregnancy due to a high risk of fetal harm. It is also not recommended for breastfeeding mothers because it may be excreted in breast milk.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Lenalidomide belongs to the immunomodulatory drug class, offering a distinct mechanism compared with proteasome inhibitors or monoclonal antibodies. It is often used in combination regimens and may provide benefits in patients who have progressed after other standard therapies.

Store Lenalidomide Glenmark at ambient temperature, preferably below 25 °C. Keep the product in its original packaging, protect it from moisture and direct light, and avoid storing it in humid environments.

Lenalidomide Glenmark is taken orally, usually as a tablet, with or without food as directed by the prescriber. Swallow the tablet whole with a glass of water and follow the dosing schedule provided by the healthcare professional.

Serious risks include thromboembolic events such as deep‑vein thrombosis, severe neutropenia leading to infection, secondary primary malignancies, and significant liver toxicity. Patients should be monitored regularly for these complications.

Lenalidomide Glenmark should not be used by pregnant women, individuals with uncontrolled infections, or patients with severe renal impairment without appropriate monitoring. It is also contraindicated in patients with known hypersensitivity to lenalidomide or any of its excipients.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Related Products

Other formulations containing Lenalidomide

A

A
A

A
A

A
A

A

Browse all products →

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Regulatory recognitions

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.

SGS GSDP Certification

GSDP Compliant from SGS

URS ISO 9001

URS ISO 9001 Certification

FDA Maharashtra

Licensed by FDA Maharashtra

IEC License DGFT

IEC License issued by DGFT