Lendormin (Brotizolam)

Brotizolam binds to the benzodiazepine site on the GABA‑A receptor complex, acting as a positive allosteric modulator. By enhancing the inhibitory action of GABA, it increases chloride ion flow into neurons, producing a calming effect that facilitates the initiation and maintenance of sleep.

The dose of Lendormin is individualized by the prescribing healthcare professional based on the patient’s age, severity of insomnia, and overall health status. The prescriber will determine the appropriate strength, timing, and duration of therapy, and patients should follow that specific instruction without deviation.

Safety data for Brotizolam in pregnancy and lactation are limited, and the drug is generally classified as contraindicated or to be avoided unless the potential benefit outweighs the risk. Women who are pregnant, planning pregnancy, or breastfeeding should discuss alternative sleep‑management strategies with their clinician.

To request Lendormin, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and the necessary import documentation.

Lendormin (Brotizolam) belongs to the benzodiazepine class, offering rapid onset and a relatively short half‑life compared with some longer‑acting benzodiazepines. Compared with non‑benzodiazepine hypnotics such as zolpidem, Brotizolam may have a higher risk of dependence but can be useful when a clinician prefers the benzodiazepine profile for certain patients.

Lendormin tablets should be stored at ambient temperature, preferably below 25 °C, in the original blister or container. Protect them from moisture, direct sunlight, and excessive heat. Keep the product out of reach of children and do not use after the expiration date printed on the packaging.

Lendormin is taken orally as a tablet. The tablet should be swallowed whole with a glass of water, preferably shortly before bedtime. Patients should avoid crushing or chewing the tablet, and they should not take it with a prolonged period of wakefulness to reduce the risk of next‑day sedation.

The most serious risks include the potential for respiratory depression, especially when combined with other central nervous system depressants, and the development of physical dependence or withdrawal syndrome after prolonged use. Paradoxical reactions such as agitation, aggression, or severe allergic responses may also occur and require immediate medical attention.

Lendormin is contraindicated in individuals with known hypersensitivity to Brotizolam or other benzodiazepines, severe respiratory insufficiency (e.g., COPD with CO₂ retention), myasthenia gravis, severe hepatic impairment, and in patients with a history of substance dependence. It should also be avoided in pregnant or nursing women unless clearly indicated by a physician.