Lentocilin S 1200 (Benzathine Benzylpenicillin)

Benzathine benzylpenicillin inhibits bacterial cell‑wall synthesis by binding to penicillin‑binding proteins, preventing the cross‑linking of peptidoglycan strands. This leads to weakened cell walls, osmotic instability and ultimately bacterial lysis, especially in actively dividing, penicillin‑sensitive organisms.

The dosage of Lentocilin S 1200 is determined by the prescribing clinician based on the specific infection, patient weight, age, renal function and treatment guidelines. Only a qualified healthcare professional should set the dose and administration schedule.

Safety data for benzathine benzylpenicillin in pregnancy and lactation are limited. It should be used only when the potential benefit justifies any possible risk to the fetus or infant, and the decision must be made by the treating physician.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed) and import documentation.

Lentocilin S 1200 provides a long‑acting intramuscular depot of benzathine benzylpenicillin, offering prolonged therapeutic levels with a single injection, unlike short‑acting penicillins that require multiple daily doses. This makes it convenient for syphilis treatment and rheumatic fever prophylaxis, though it shares the same allergy profile as other penicillins.

Store Lentocilin S 1200 at ambient temperature, below 25 °C, in its original packaging. Protect the product from moisture, direct sunlight and extreme temperatures to maintain potency and sterility.

Lentocilin S 1200 is given by deep intramuscular injection, typically into the gluteal muscle. The injection should be performed by a qualified healthcare professional using aseptic technique and rotating injection sites when multiple doses are required.

The most serious risks include anaphylactic reactions, severe neutropenia or agranulocytosis, serum‑sickness‑like reactions, and rare severe skin disorders such as Stevens‑Johnson syndrome. Immediate medical attention is required if any of these symptoms occur.

Patients with a known hypersensitivity to any penicillin or beta‑lactam antibiotic should avoid Lentocilin S 1200. It is also contraindicated in individuals with a history of severe allergic reactions to penicillins or those who have experienced anaphylaxis after prior penicillin exposure.