Product image of Leonore (Ethinylestradiol, Levonorgestrel) supplied by GNH India

Leonore

Active Ingredient:
Ethinylestradiol, Levonorgestrel
Origin:
EU

Leonore (Ethinylestradiol, Levonorgestrel)

Ethinylestradiol and Levonorgestrel, the active ingredients in Leonore, are a combined oral contraceptive presented as a tablet for oral use. They work together to prevent pregnancy in women of reproductive age by inhibiting ovulation, thickening cervical mucus, and modifying the endometrium, providing reliable hormonal birth control.

GNH India supplies Leonore as a licensed, GDP‑compliant international pharmaceutical supplier, delivering the product to hospitals, pharmacies and clinics worldwide with adherence to quality standards and regulatory requirements.

Manufacturer / TM Owner

Rowex Ltd

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Indications & Clinical Uses

Leonore, a combined oral contraceptive, acts on the hormonal regulation pathway to prevent pregnancy.

  • Contraception: prevention of pregnancy in women of reproductive age.
  • Menstrual cycle regulation: helps achieve more regular and predictable periods.
  • Acne improvement: may reduce hormonal acne associated with menstrual cycles.

How It Works

  • Ethinylestradiol and levonorgestrel combine to suppress the mid‑cycle surge of luteinising hormone (LH) and follicle‑stimulating hormone (FSH), thereby inhibiting ovulation. Ethinylestradiol provides estrogenic activity that stabilises the endometrial lining, while levonorgestrel, a progestogen, thickens cervical mucus and induces endometrial changes that reduce the likelihood of implantation. Together they maintain consistent hormone levels that prevent the follicular development required for conception.

Side Effects

Leonore may cause a range of adverse reactions, which are generally classified by frequency and severity.

Common Side Effects

  • Nausea: mild stomach upset.
  • Headache: tension‑type or migraine‑like pain.
  • Breast tenderness: soreness or swelling.
  • Irregular bleeding: spotting or breakthrough bleeding.

Serious or Rare Side Effects

  • Deep vein thrombosis: clot formation in deep veins.
  • Pulmonary embolism: clot traveling to lungs.
  • Severe allergic reaction: rash, swelling, difficulty breathing.

Precautions & Warnings

Before prescribing Leonore, several precautions should be considered to ensure safe use.

  • Contraindication: avoid in women with known thromboembolic disorders.
  • Smoking: do not use if over 35 years and a smoker.
  • Cardiovascular risk: assess history of hypertension, stroke, or myocardial infarction.
  • Liver disease: use with caution in patients with active liver disease.
  • Pregnancy: contraindicated; pregnancy must be ruled out before initiation.
  • Store at ambient temperature: keep below 25 °C in the original packaging, protect from moisture and light.

Avoid Interactions

Leonore can interact with other medicines, affecting its efficacy or safety.

Major Interactions (Avoid)

  • Anticoagulants: may reduce effectiveness of warfarin, requiring monitoring.
  • Antiepileptic enzyme inducers (e.g., carbamazepine, phenytoin): can lower contraceptive hormone levels, increasing pregnancy risk.
  • Certain antibiotics (e.g., rifampicin): may decrease hormonal concentrations.

Moderate Interactions (Monitor Closely)

  • Antifungals (e.g., ketoconazole): may increase hormone levels, raising side‑effect risk.
  • St. John’s wort: may reduce contraceptive effectiveness.
  • Selective serotonin reuptake inhibitors (SSRIs): may increase risk of mood changes.

Frequently Asked Questions

Leonore is a combined oral contraceptive indicated for the prevention of pregnancy in women of reproductive age. By delivering both estrogen and progestogen, it provides reliable hormonal birth control and may also help regulate menstrual cycles and improve hormonal acne.

The ethinylestradiol component supplies estrogenic activity that stabilises the endometrium, while levonorgestrel acts as a progestogen. Together they suppress the mid‑cycle surge of luteinising hormone and follicle‑stimulating hormone, preventing ovulation, thickening cervical mucus and altering the uterine lining to reduce the chance of implantation.

The dosing regimen for Leonore is determined by the prescribing healthcare professional. Typically, it is taken as one tablet daily at the same time each day, but the exact schedule and any missed‑dose instructions are provided by the prescriber.

Leonore is contraindicated in pregnancy (Category X) and must not be started in women who are pregnant or suspect they might be. While limited data exist for breastfeeding, the progestogen component may affect milk production, so use is generally discouraged unless clearly indicated by a physician.

To order Leonore, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams across international markets, and will request verification of trade or institutional credentials. The team then replies with pricing, availability, shipping details and any necessary import documentation.

Leonore contains standard doses of ethinylestradiol and levonorgestrel, offering efficacy comparable to other combined oral contraceptives. Differences among products usually relate to hormone dose strength, pill regimen (21‑day vs 24‑day cycles), and specific formulation excipients, which may influence side‑effect profiles or tolerability for individual patients.

Leonore tablets should be stored at ambient temperature, preferably below 25 °C, in the original blister pack or container. Protect them from excess moisture, direct sunlight and heat. Do not store in bathrooms or near kitchen appliances that generate steam.

Leonore is taken orally as a tablet. The recommended practice is to swallow one tablet each day, preferably at the same time, with or without food. Consistent daily intake maintains hormone levels and maximises contraceptive effectiveness.

Serious risks include thromboembolic events such as deep‑vein thrombosis, pulmonary embolism, stroke and myocardial infarction. Women should seek immediate medical attention if they experience sudden leg pain, shortness of breath, chest pain, severe headache, or visual disturbances, as these may signal a life‑threatening complication.

Leonore should not be used by women with a history of thromboembolic disorders, uncontrolled hypertension, certain cardiovascular diseases, active liver disease, known or suspected pregnancy, or those who are smokers over the age of 35. It is also contraindicated in individuals with known hypersensitivity to any component of the tablet.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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