Product image of Lercanidipin Actavis (Lercanidipine Hydrochloride) supplied by GNH India

Lercanidipin Actavis

Active Ingredient:
Lercanidipine Hydrochloride
Origin:
EU

Lercanidipin Actavis (Lercanidipine Hydrochloride)

Lercanidipine, the active ingredient in Lercanidipin Actavis, is a calcium channel blocker presented as a tablet for oral use. It is prescribed to lower elevated blood pressure in adult patients with hypertension.
GNH India supplies Lercanidipin Actavis as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Actavis Group Ptc Ehf.

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Lercanidipine is a dihydropyridine calcium‑channel blocker used in the management of arterial hypertension.

  • Hypertension: reduces systolic and diastolic blood pressure, helping to prevent cardiovascular complications.

How It Works

  • Lercanidipine selectively inhibits L‑type calcium channels in vascular smooth muscle. By blocking calcium influx, it prevents contraction of arterial smooth muscle, leading to vasodilation, decreased peripheral vascular resistance, and ultimately a reduction in systemic blood pressure.

Side Effects

Lercanidipine may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects

  • Headache: mild to moderate intensity.
  • Flushing: sensation of warmth, especially on the face.
  • Peripheral edema: swelling of the ankles or lower legs.
  • Dizziness: often related to blood pressure lowering.
  • Tachycardia: increased heart rate.
  • Gastrointestinal discomfort: nausea or abdominal pain.

Serious or Rare Side Effects

  • Severe hypotension: marked drop in blood pressure requiring medical attention.
  • Angio‑edema: swelling of lips, tongue, or throat.
  • Hepatic dysfunction: abnormal liver enzymes.
  • Allergic reactions: rash, pruritus, or urticaria.

Precautions & Warnings

Before initiating therapy, consider the following safety measures.

  • Cardiovascular assessment: evaluate baseline blood pressure and heart rate.
  • Concomitant antihypertensives: monitor for additive hypotensive effects.
  • Liver impairment: use with caution in patients with hepatic disease.
  • Elderly patients: start at the lowest effective dose and monitor closely.
  • Pregnancy and lactation: avoid unless clearly indicated by a physician.
  • Store at ambient temperature: keep below 25 °C, retain in original packaging, and protect from moisture.

Avoid Interactions

Lercanidipine can interact with several drug classes, influencing its efficacy or safety.

Major Interactions (Avoid)

  • Strong CYP3A4 inhibitors (e.g., ketoconazole, clarithromycin): may increase plasma concentrations.
  • Grapefruit juice: can markedly raise drug levels.

Moderate Interactions (Monitor Closely):\n- Other antihypertensives (e.g., ACE inhibitors, diuretics): risk of additive hypotension.

  • CYP3A4 inducers (e.g., rifampicin, carbamazepine): may reduce therapeutic effect.
  • Simvastatin: increased risk of statin‑related myopathy.

Frequently Asked Questions

Lercanidipin Actavis contains lercanidipine hydrochloride, a calcium‑channel blocker indicated for the treatment of essential hypertension in adult patients. It helps lower elevated blood pressure and reduces the risk of cardiovascular events associated with uncontrolled hypertension.

Lercanidipine selectively blocks L‑type calcium channels in arterial smooth muscle. This inhibition prevents calcium‑induced contraction, causing vasodilation of peripheral arteries, lowering systemic vascular resistance and thereby reducing systolic and diastolic blood pressure.

The dose of lercanidipine is individualized by the prescribing healthcare professional based on the patient’s blood pressure, response, and tolerability. The prescriber determines the appropriate strength and dosing schedule.

Safety of lercanidipine in pregnancy and lactation has not been established. It should be used only if the potential benefit justifies the potential risk to the fetus or infant, and only under medical supervision.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Both lercanidipine and amlodipine belong to the dihydropyridine class of calcium‑channel blockers and lower blood pressure by vasodilation. Lercanidipine has a longer half‑life and may provide smoother blood‑pressure control with a lower incidence of reflex tachycardia, but individual response varies and choice depends on clinician judgment.

Store the tablets at ambient temperature, preferably below 25 °C. Keep them in the original blister pack or container, protect from moisture and direct sunlight, and keep out of reach of children.

Lercanidipin Actavis is taken orally, usually once daily with or without food, as directed by the prescribing physician. Swallow the tablet whole with a glass of water; do not crush or chew unless specifically instructed.

Serious adverse events, though rare, include severe hypotension, angio‑edema, and hepatic dysfunction. Patients should seek immediate medical attention if they experience sudden dizziness, fainting, swelling of the face or throat, or signs of liver injury such as jaundice.

Lercanidipine is contraindicated in patients with known hypersensitivity to lercanidipine or any component of the formulation, and in those with severe aortic stenosis or unstable angina. Caution is also advised for patients with significant liver impairment.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.