Product image of Lercanidipina Accord (Lercanidipine Hydrochloride) supplied by GNH India

Lercanidipina Accord

Active Ingredient:
Lercanidipine Hydrochloride
Origin:
EU

Lercanidipina Accord (Lercanidipine Hydrochloride)

Lercanidipine, the active ingredient in Lercanidipina Accord, is a calcium channel blocker presented as an oral dosage form for oral use. It is employed to lower elevated blood pressure in adults diagnosed with hypertension.
GNH India supplies Lercanidipina Accord as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Accord Healthcare S.L.U.

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

  • Lercanidipine is a dihydropyridine calcium‑channel blocker indicated for the management of hypertension, helping to achieve controlled blood pressure levels.
  • Hypertension: reduces systemic vascular resistance and lowers arterial pressure, improving cardiovascular risk profile.

How It Works

  • Lercanidipine selectively inhibits L‑type calcium channels in vascular smooth muscle, preventing calcium influx that is necessary for contraction. This leads to relaxation of arterial smooth muscle, vasodilation, and a consequent reduction in peripheral vascular resistance, thereby lowering blood pressure.

Side Effects

Lercanidipine may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects

  • Headache
  • Flushing
  • Peripheral edema
  • Dizziness
  • Tachycardia
  • Nausea

Serious or Rare Side Effects

  • Severe hypotension
  • Myocardial infarction
  • Angioedema
  • Hepatic injury
  • Severe bradycardia
  • Anaphylactic reactions

Precautions & Warnings

Before initiating therapy, clinicians should consider several safety aspects.

  • Blood pressure monitoring: check baseline and periodic readings to avoid excessive hypotension.
  • Hepatic function: use caution in patients with moderate to severe liver impairment.
  • Concomitant antihypertensives: adjust doses to prevent additive blood‑pressure lowering effects.
  • Heart failure: evaluate for fluid retention and monitor cardiac status.
  • Discontinuation: avoid abrupt cessation; taper if clinically indicated.
  • Store at room temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Lercanidipine can interact with several drug classes, influencing its efficacy and safety.

Major Interactions (Avoid)

  • Strong CYP3A4 inhibitors (e.g., ketoconazole, itraconazole): may increase plasma concentrations.
  • Other calcium‑channel blockers: additive vasodilatory effect can cause profound hypotension.
  • Grapefruit juice: enhances systemic exposure, raising risk of adverse events.
  • Concurrent antihypertensives with potent vasodilatory action: may lead to unsafe blood‑pressure drops.

Moderate Interactions (Monitor Closely)

  • CYP3A4 inducers (e.g., rifampin, carbamazepine): may reduce therapeutic levels.
  • Diuretics: monitor electrolytes and volume status.
  • Non‑steroidal anti‑inflammatory drugs (NSAIDs): can blunt antihypertensive response.
  • Beta‑blockers: observe for bradycardia and excessive blood‑pressure reduction.

Frequently Asked Questions

Lercanidipina Accord contains lercanidipine, a calcium‑channel blocker prescribed to treat hypertension. By lowering elevated blood pressure, it helps reduce the risk of cardiovascular events such as stroke and heart attack in adult patients diagnosed with high blood pressure.

Lercanidipine selectively blocks L‑type calcium channels in the smooth muscle of arterial walls. This inhibition prevents calcium‑mediated contraction, causing vasodilation, decreasing peripheral resistance, and ultimately lowering systemic blood pressure.

The appropriate dose of lercanidipine is determined by the prescribing clinician based on the patient’s blood‑pressure profile, age, renal and hepatic function, and concomitant medications. Dosage adjustments are made individually; patients should follow the prescriber’s instructions exactly.

Safety data for lercanidipine in pregnancy are limited, and the drug is generally not recommended unless the potential benefit outweighs the risk. It is also excreted in breast milk, so use during lactation should be avoided or closely supervised by a healthcare professional.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Both lercanidipine and amlodipine belong to the dihydropyridine class of calcium‑channel blockers and lower blood pressure by vasodilation. Lercanidipine has a longer half‑life and may provide smoother blood‑pressure control with potentially fewer dose‑related side effects, though individual response varies.

Store the product at room temperature, preferably below 25 °C. Keep the tablets in their original blister pack or container, protect them from moisture, heat, and direct sunlight to maintain potency throughout the shelf life.

Lercanidipina Accord is taken orally, usually once daily, with or without food. The tablet should be swallowed whole with a glass of water. Patients should not crush, chew, or split the tablet unless specifically instructed by a healthcare professional.

Serious adverse events include severe hypotension, myocardial infarction, angioedema, and hepatic injury. Patients should seek immediate medical attention if they experience sudden dizziness, fainting, chest pain, swelling of the face or throat, or signs of liver dysfunction such as jaundice.

Lercanidipine is contraindicated in patients with known hypersensitivity to the drug or any component of the formulation. It should also be avoided in individuals with severe aortic stenosis, unstable angina, or cardiogenic shock, as the vasodilatory effect may worsen these conditions.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.