Product image of Lercanidipina Farmoz (Lercanidipine Hydrochloride) supplied by GNH India

Lercanidipina Farmoz

Active Ingredient:
Lercanidipine Hydrochloride
Origin:
EU

Lercanidipina Farmoz (Lercanidipine Hydrochloride)

Lercanidipine, the active ingredient in Lercanidipina Farmoz, is a calcium channel blocker presented as an oral tablet for oral use. It treats hypertension by relaxing arterial smooth muscle and lowering blood pressure in adult patients.
GNH India supplies Lercanidipina Farmoz as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Farmoz - Sociedade Técnico Medicinal, S.A.

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Indications & Clinical Uses

  • Lercanidipine is used to manage conditions related to elevated blood pressure.
  • Hypertension: reduces systolic and diastolic blood pressure by relaxing arterial smooth muscle, helping to prevent cardiovascular complications.

How It Works

  • Lercanidipine selectively inhibits L‑type calcium channels in vascular smooth muscle cells, decreasing calcium influx. This leads to arterial vasodilation, reduced peripheral vascular resistance, and consequently lower systemic blood pressure without significant effect on cardiac contractility.

Side Effects

Lercanidipine may cause a range of adverse reactions, which are generally classified by frequency.

Common Side Effects

  • Headache: mild to moderate headache often occurring at treatment initiation.
  • Flushing: transient warmth and redness of the skin.
  • Peripheral edema: swelling of the ankles or lower legs.
  • Dizziness: light‑headed sensation, especially when standing quickly.

Serious or Rare Side Effects

  • Severe hypotension: marked drop in blood pressure leading to fainting.
  • Angio‑edema: rapid swelling of face, lips, tongue or throat requiring urgent care.
  • Myocardial infarction: rare occurrence of heart attack in susceptible patients.

Precautions & Warnings

  • When prescribing Lercanidipine, clinicians should consider the following precautions.
  • Monitor blood pressure: adjust dose if target levels are not achieved.
  • Assess liver function: use with caution in hepatic impairment.
  • Avoid in patients with severe aortic stenosis: risk of hypotension.
  • Caution in elderly: increased sensitivity to vasodilatory effects.
  • Store at ambient temperature: keep in original container, protect from moisture and light.

Avoid Interactions

Lercanidipine can interact with several medicines, affecting its efficacy or safety.

Major Interactions (Avoid)

  • Concomitant use with strong CYP3A4 inhibitors (e.g., ketoconazole, clarithromycin): may increase plasma levels and risk of hypotension.
  • Co‑administration with other antihypertensives (e.g., ACE inhibitors, diuretics) without monitoring: can cause excessive blood pressure drop.
  • Use with grapefruit juice: enhances drug exposure leading to adverse effects.

Moderate Interactions (Monitor Closely)

  • CYP3A4 inducers (e.g., rifampicin, carbamazepine): may reduce effectiveness.
  • Non‑steroidal anti‑inflammatory drugs (NSAIDs): may blunt antihypertensive response.
  • Alcohol: can potentiate vasodilatory effects, increasing dizziness.

Frequently Asked Questions

Lercanidipina Farmoz contains lercanidipine, a calcium channel blocker indicated for the treatment of hypertension. By relaxing arterial smooth muscle, it helps lower elevated blood pressure and reduces the risk of cardiovascular events in adult patients.

Lercanidipine selectively blocks L‑type calcium channels in vascular smooth muscle, reducing calcium entry into the cells. This causes arterial vasodilation, decreases peripheral vascular resistance, and ultimately lowers systemic blood pressure.

The appropriate dose of Lercanidipina Farmoz is determined by the prescribing healthcare professional based on the individual’s clinical condition, response to therapy, and any concomitant medications. Patients should follow the prescriber’s instructions exactly.

Safety of lercanidipine in pregnancy and lactation has not been fully established. It should only be used if the potential benefit justifies the potential risk to the fetus or infant, and the decision must be made by a qualified healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Lercanidipine belongs to the dihydropyridine calcium‑channel blocker class, offering potent arterial vasodilation with a relatively low effect on heart rate. Compared with ACE inhibitors or beta‑blockers, it may cause fewer cough or fatigue symptoms but can be associated with peripheral edema and flushing.

Store Lercanidipina Farmoz at ambient temperature, below 25 °C. Keep the tablets in the original packaging, protect them from moisture, light, and excessive heat to maintain product stability.

Lercanidipina Farmoz is taken orally as a tablet. It should be swallowed whole with a glass of water, with or without food, as directed by the prescribing clinician.

Serious adverse events, although rare, include severe hypotension, angio‑edema (rapid swelling of the face, lips, tongue or throat), and myocardial infarction. Patients should seek immediate medical attention if they experience symptoms such as fainting, severe dizziness, swelling of the airway, or chest pain.

Lercanidipina Farmoz should be avoided in individuals with known hypersensitivity to lercanidipine or any excipients, and in patients with severe aortic stenosis or uncontrolled hypotension. Caution is also advised for the elderly and those with significant liver impairment.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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