Product image of Lercanidipina Jaba (Lercanidipine Hydrochloride) supplied by GNH India

Lercanidipina Jaba

Active Ingredient:
Lercanidipine Hydrochloride
Origin:
EU

Lercanidipina Jaba (Lercanidipine Hydrochloride)

Lercanidipine Hydrochloride, the active ingredient in Lercanidipina Jaba, is a calcium channel blocker presented as an oral tablet for oral use. It is indicated for the management of hypertension in adult patients and works by relaxing vascular smooth muscle, thereby lowering systemic vascular resistance.

GNH India supplies Lercanidipina Jaba as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to Good Distribution Practice and provides regulatory documentation to support import and clinical use.

Manufacturer / TM Owner

Jaba Recordati, S.A.

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Lercanidipine Hydrochloride is used to treat conditions related to elevated arterial pressure.

  • Hypertension: reduces high blood pressure, helping to prevent cardiovascular complications.

How It Works

  • Lercanidipine Hydrochloride selectively inhibits L-type calcium channels in vascular smooth muscle cells. This inhibition prevents calcium influx, leading to relaxation of arterial smooth muscle, vasodilation, and a consequent decrease in peripheral vascular resistance, which lowers systemic blood pressure.

Side Effects

Lercanidipine Hydrochloride may cause a range of adverse reactions, which are categorized by frequency and severity.

Common Side Effects

  • Headache: mild to moderate pain often occurring shortly after dosing.
  • Flushing: transient redness and warmth of the skin.
  • Peripheral edema: swelling of the lower limbs due to fluid accumulation.
  • Dizziness: sensation of light‑headedness, especially when standing quickly.

Serious or Rare Side Effects

  • Severe hypotension: marked drop in blood pressure that may cause fainting.
  • Angioedema: rapid swelling of the face, lips, tongue, or throat requiring urgent care.
  • Myocardial infarction: rare occurrence of heart attack associated with abrupt blood pressure changes.

Precautions & Warnings

Before initiating therapy, clinicians should consider several safety factors.

  • Blood pressure monitoring: check baseline and periodic readings to assess response.
  • Avoid abrupt discontinuation: tapering may be needed to prevent rebound hypertension.
  • Hepatic impairment: use with caution in patients with liver dysfunction.
  • Elderly patients: start at lower doses due to increased sensitivity.
  • Concomitant CYP3A4 inhibitors: may raise drug levels, requiring dose adjustment.
  • Store at room temperature: keep in the original pack, protect from moisture and direct sunlight.

Avoid Interactions

Lercanidipine Hydrochloride can interact with several medicines, affecting its efficacy or safety.

Major Interactions (Avoid)

  • Strong CYP3A4 inhibitors (e.g., ketoconazole, itraconazole): may increase plasma concentrations.
  • Strong CYP3A4 inducers (e.g., rifampicin, carbamazepine): may reduce therapeutic effect.
  • Concurrent use with other antihypertensives: risk of excessive hypotension.

Moderate Interactions (Monitor Closely):\n- Grapefruit juice: can elevate drug exposure.

  • Diuretics: may enhance hypotensive response.
  • Beta‑blockers: additive blood pressure lowering may require dose titration.

Frequently Asked Questions

Lercanidipina Jaba contains Lercanidipine Hydrochloride, which is prescribed to lower elevated blood pressure in adults diagnosed with hypertension. By controlling blood pressure, it helps reduce the risk of cardiovascular events such as stroke and heart attack.

Lercanidipine Hydrochloride blocks L-type calcium channels in the smooth muscle of arteries. This blockade prevents calcium from entering the cells, causing the vessels to relax and widen (vasodilation), which lowers peripheral resistance and consequently reduces systemic blood pressure.

The appropriate dose of Lercanidipina Jaba is determined by the prescribing healthcare professional based on the patient’s clinical condition, response to therapy, and any concomitant medications. Dosage adjustments are made individually and should follow the prescriber’s instructions.

Safety data for Lercanidipine Hydrochloride in pregnancy and lactation are limited. It should only be used if the potential benefit justifies the potential risk to the fetus or infant. Women who are pregnant, planning pregnancy, or breastfeeding should discuss alternatives with their healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, and will request verification of trade or institutional credentials before providing pricing, availability, shipping details, and any necessary import documentation.

Both Lercanidipine and amlodipine belong to the dihydropyridine class of calcium channel blockers and lower blood pressure by vasodilation. Lercanidipine has a longer half‑life, allowing once‑daily dosing, and may be associated with a lower incidence of peripheral edema compared with amlodipine, though individual responses vary.

Store the tablets at room temperature, below 25 °C, in the original packaging. Keep them away from moisture, direct sunlight, and excessive heat to maintain product stability throughout its shelf life.

Lercanidipina Jaba is taken orally, usually once daily with or without food, as directed by the prescriber. Swallow the tablet whole with a glass of water; do not crush or chew unless specifically instructed.

Serious adverse events include severe hypotension, angioedema (rapid swelling of the face, lips, tongue, or throat), and rare cases of myocardial infarction. Patients should seek immediate medical attention if they experience sudden dizziness, fainting, swelling of the airway, or chest pain.

Lercanidipina Jaba is contraindicated in patients with known hypersensitivity to Lercanidipine or any component of the formulation. It should also be avoided in individuals with severe aortic stenosis or uncontrolled heart failure unless a specialist determines that benefits outweigh risks.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.