Product image of Lercanidipina Mylan (Lercanidipine Hydrochloride) supplied by GNH India

Lercanidipina Mylan

Active Ingredient:
Lercanidipine Hydrochloride
Origin:
EU

Lercanidipina Mylan (Lercanidipine Hydrochloride)

Lercanidipine, the active ingredient in Lercanidipina Mylan, is a calcium channel blocker presented as an oral tablet for systemic use. It is prescribed to lower elevated blood pressure in adult patients with hypertension and is marketed in the European Union.\n\nGNH India supplies Lercanidipina Mylan as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, providing consistent quality and regulatory compliance.

Manufacturer / TM Owner

Viatris Limited

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Indications & Clinical Uses

  • Lercanidipine is a dihydropyridine calcium‑channel blocker used to manage arterial hypertension.\n\nHypertension: reduces systolic and diastolic blood pressure by causing arterial vasodilation, helping to achieve target blood pressure levels.

How It Works

  • Lercanidipine selectively blocks L‑type calcium channels on vascular smooth‑muscle cells, inhibiting calcium influx. This leads to relaxation of arterial smooth muscle, resulting in vasodilation and a consequent reduction in peripheral vascular resistance and blood pressure.

Side Effects

  • Lercanidipine may cause a range of adverse reactions, most of which are mild and reversible.\n\nCommon Side Effects:\n- Headache\n- Flushing\n- Peripheral edema\n- Dizziness\n- Tachycardia\n- Palpitations\n\nSerious or Rare Side Effects:\n- Angioedema\n- Severe hypotension\n- Myocardial infarction\n- Hepatic dysfunction\n- Severe allergic reactions\n- Neutropenia

Precautions & Warnings

  • Before initiating therapy, clinicians should consider several safety aspects.\n\nMonitor blood pressure: ensure adequate control without excessive hypotension.\nAssess hepatic function: use caution in patients with liver impairment.\nAvoid abrupt discontinuation: taper to prevent rebound hypertension.\nReview concomitant antihypertensives: adjust doses to avoid additive effects.\nStore at ambient temperature: keep in the original packaging, protect from moisture.

Avoid Interactions

  • Lercanidipine can interact with several drug classes, requiring careful management.\n\nMajor Interactions (Avoid):\n- Strong CYP3A4 inhibitors (e.g., ketoconazole, clarithromycin): may increase plasma levels.\n- Concomitant use with other calcium‑channel blockers: risk of additive hypotension.\n- Grapefruit juice: can markedly raise drug exposure.\n- Other potent antihypertensives: may cause severe blood pressure drops.\n\nModerate Interactions (Monitor Closely):\n- CYP3A4 inducers (e.g., rifampin, carbamazepine): may reduce efficacy.\n- Diuretics: may enhance hypotensive effect.\n- Beta‑blockers: possible additive bradycardia.\n- NSAIDs: may attenuate antihypertensive response.

Frequently Asked Questions

Lercanidipina Mylan contains lercanidipine, a calcium‑channel blocker indicated for the treatment of hypertension. It helps lower elevated blood pressure by relaxing arterial smooth muscle, thereby reducing vascular resistance.

Lercanidipine selectively inhibits L‑type calcium channels on vascular smooth‑muscle cells. By blocking calcium entry, it causes arterial vasodilation, which decreases peripheral resistance and leads to a reduction in systolic and diastolic blood pressure.

The appropriate dose of lercanidipine is determined by the prescribing healthcare professional based on the patient’s clinical condition, response to therapy, and any concomitant medications. Dosage adjustments are made individually.

The safety of lercanidipine in pregnancy and lactation has not been established. It should only be used if the potential benefit justifies the potential risk to the fetus or infant, and decisions are made in consultation with a qualified healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Compared with non‑dihydropyridine calcium‑channel blockers, lercanidipine primarily causes arterial vasodilation with minimal effect on cardiac conduction. It offers a once‑daily dosing schedule and a favorable side‑effect profile relative to some older agents, but individual response varies.

Store at ambient temperature: keep the tablets in the original container, protect from moisture and direct sunlight, and avoid exposure to temperatures above 25 °C to maintain product stability.

Lercanidipina Mylan is taken orally, usually once daily, with or without food. The tablet should be swallowed whole with a glass of water and not crushed or chewed.

Serious risks include severe hypotension, angioedema, myocardial infarction, and hepatic dysfunction. Patients should be monitored for signs of these events, and therapy should be discontinued immediately if they occur.

Lercanidipine is contraindicated in patients with known hypersensitivity to the drug or any component of the formulation, and it should be used with caution in individuals with severe hepatic impairment, unstable angina, or a history of significant hypotensive reactions.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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