Product image of Lercanidipine Hcl Aurobindo (Lercanidipine Hydrochloride) supplied by GNH India

Lercanidipine Hcl Aurobindo

Active Ingredient:
Lercanidipine Hydrochloride
Origin:
EU

Lercanidipine Hcl Aurobindo (Lercanidipine Hydrochloride)

Lercanidipine hydrochloride, the active ingredient in Lercanidipine Hcl Aurobindo, is a calcium channel blocker presented as an oral tablet for oral use. It is indicated for the management of essential hypertension in adult patients, helping to lower systolic and diastolic blood pressure.

GNH India supplies Lercanidipine Hcl Aurobindo as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Aurobindo Pharma B.V.

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Lercanidipine is used to treat hypertension, a condition characterized by elevated arterial pressure.

  • Essential hypertension: reduces systolic and diastolic blood pressure in adults with primary hypertension
  • Isolated systolic hypertension: helps control elevated systolic pressure in older patients
  • Hypertension with diabetes: contributes to blood pressure control as part of combination therapy

How It Works

  • Lercanidipine selectively inhibits L-type calcium channels on vascular smooth‑muscle cells, preventing calcium influx that is required for contraction. This vasodilatory effect reduces peripheral vascular resistance, leading to a gradual decline in both systolic and diastolic blood pressure without significant impact on heart rate.

Side Effects

Lercanidipine may cause a range of adverse reactions, which are categorized by frequency.

Common Side Effects

  • Headache: mild to moderate pain often occurring after dose initiation
  • Flushing: transient warmth and redness of the skin
  • Peripheral edema: swelling of ankles or feet due to fluid accumulation
  • Dizziness: sensation of light‑headedness, especially when standing quickly

Serious or Rare Side Effects

  • Angioedema: swelling of face, lips, tongue that may compromise airway
  • Severe hypotension: marked drop in blood pressure causing fainting or shock
  • Hepatic dysfunction: abnormal liver enzymes or hepatitis

Precautions & Warnings

Before initiating therapy, clinicians should consider several safety measures.

  • Monitor blood pressure: adjust therapy based on regular measurements
  • Assess liver function: use caution in patients with hepatic impairment
  • Avoid abrupt discontinuation: may lead to rebound hypertension
  • Use cautiously in the elderly: increased sensitivity to hypotensive effects
  • Store at room temperature: keep in original packaging, protect from moisture

Avoid Interactions

Lercanidipine can interact with other medicines, requiring attention to avoid adverse outcomes.

Major Interactions (Avoid)

  • Strong CYP3A4 inhibitors (e.g., ketoconazole, clarithromycin): may increase plasma concentrations
  • Concomitant use with other antihypertensives: risk of excessive hypotension
  • Grapefruit juice: can raise drug levels and enhance effects

Moderate Interactions (Monitor Closely)

  • Diuretics: monitor electrolytes and renal function
  • Beta‑blockers: observe for additive heart‑rate reduction
  • Antacids containing aluminum or magnesium: may affect absorption if taken simultaneously

Frequently Asked Questions

Lercanidipine Hcl Aurobindo is prescribed to lower elevated blood pressure in adults with essential hypertension. By relaxing the smooth muscle of blood vessels, it helps achieve target blood‑pressure goals and reduces the risk of cardiovascular complications associated with chronic high blood pressure.

Lercanidipine blocks L‑type calcium channels on vascular smooth‑muscle cells, preventing calcium entry that triggers contraction. This selective inhibition causes arterial vasodilation, decreasing peripheral resistance and consequently lowering both systolic and diastolic blood pressure without a pronounced effect on heart rate.

The appropriate dose of Lercanidipine is individualized by the prescribing healthcare professional based on the patient’s blood‑pressure profile, response to therapy, and any co‑existing medical conditions. Dosage adjustments are made according to clinical judgment and regular monitoring.

Safety data for Lercanidipine in pregnancy and lactation are limited. It should only be used when the potential benefit to the mother outweighs any possible risk to the fetus or infant, and only under close medical supervision.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Both Lercanidipine and amlodipine belong to the dihydropyridine class and lower blood pressure by vasodilation. Lercanidipine has a longer half‑life and may be associated with a lower incidence of peripheral edema, while amlodipine is often dosed once daily and has a well‑established safety profile. Choice depends on individual patient response and physician preference.

Store the tablets at room temperature, preferably below 25 °C. Keep them in the original packaging to protect from moisture and light, and ensure the container is tightly closed until use.

Lercanidipine is taken orally, usually as a whole tablet with a glass of water. It can be taken with or without food, but patients should follow the prescribing physician’s instructions regarding timing and any specific dietary considerations.

Serious adverse events, although rare, include angioedema, severe hypotension that may lead to syncope or shock, and hepatic dysfunction manifested by elevated liver enzymes or hepatitis. Patients should seek immediate medical attention if they experience swelling of the face or throat, sudden dizziness, or signs of liver injury.

Lercanidipine is contraindicated in patients with known hypersensitivity to the drug or any component of the formulation. Caution is advised for individuals with severe hepatic impairment, unstable angina, or those taking strong CYP3A4 inhibitors, as these conditions may increase the risk of adverse effects.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.