Product image of Lercanidipine Hcl Viatris (Lercanidipine Hydrochloride) supplied by GNH India

Lercanidipine Hcl Viatris

Active Ingredient:
Lercanidipine Hydrochloride
Origin:
EU

Lercanidipine Hcl Viatris (Lercanidipine Hydrochloride)

Lercanidipine Hydrochloride, the active ingredient in Lercanidipine Hcl Viatris, is a calcium channel blocker presented as an oral tablet for oral use. It lowers elevated blood pressure and is indicated for the management of hypertension in adult patients. It is typically prescribed when monotherapy or combination therapy is required to achieve target blood pressure.

GNH India supplies Lercanidipine Hcl Viatris as a licensed, GDP‑compliant international pharmaceutical supplier. We provide the product to hospitals, pharmacies and clinics worldwide, adhering to stringent quality standards and regulatory requirements to ensure consistent potency and safety for patients.

Manufacturer / TM Owner

Viatris Limited

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Indications & Clinical Uses

Lercanidipine Hydrochloride is used to treat conditions related to elevated arterial pressure.

  • Essential hypertension: reduces systolic and diastolic blood pressure to target levels.
  • Isolated systolic hypertension: lowers high systolic pressure while maintaining diastolic stability.
  • Hypertension in patients with metabolic syndrome: assists in achieving blood pressure control alongside lifestyle measures.

How It Works

  • Lercanidipine Hydrochloride selectively inhibits L-type calcium channels on vascular smooth muscle cells, decreasing calcium influx. This results in arterial vasodilation, reduced peripheral vascular resistance, and consequently lower systemic blood pressure without significant negative inotropic effects.

Side Effects

Adverse reactions may occur with Lercanidipine use.

Common Side Effects

  • Headache: mild to moderate intensity.
  • Flushing: transient warmth and redness.
  • Peripheral edema: swelling of ankles or feet.
  • Dizziness: especially upon standing.
  • Tachycardia: increased heart rate.
  • Fatigue: general feeling of tiredness.

Serious or Rare Side Effects

  • Severe hypotension: marked drop in blood pressure requiring medical attention.
  • Myocardial infarction: rare occurrence of heart attack.
  • Angioedema: swelling of face, lips, or throat.
  • Hepatic dysfunction: abnormal liver enzyme elevations.
  • Severe allergic reaction: rash, itching, or anaphylaxis.
  • Cardiac conduction disturbances: heart block or arrhythmias.

Precautions & Warnings

Before initiating therapy, consider the following precautions.

  • Monitor blood pressure: check regularly after starting and after dose changes.
  • Avoid abrupt discontinuation: taper under medical supervision to prevent rebound hypertension.
  • Caution in hepatic impairment: dose adjustment may be required.
  • Use with caution in elderly: increased sensitivity to hypotensive effects.
  • Review concomitant medications: assess for potential drug interactions.
  • Store at ambient temperature: keep below 25°C, retain original packaging, protect from moisture.

Avoid Interactions

Lercanidipine may interact with several medicines; assess the risk before co‑administration.

Major Interactions (Avoid)

  • Strong CYP3A4 inhibitors (e.g., ketoconazole): may increase plasma concentrations.
  • Co‑administration with other antihypertensives: can cause excessive hypotension.
  • Grapefruit juice: may elevate drug exposure.

Moderate Interactions (Monitor Closely)

  • Diuretics: may enhance antihypertensive effect, requiring BP monitoring.
  • Beta‑blockers: combined use may need dose adjustments.
  • CYP3A4 inducers (e.g., rifampicin): may reduce therapeutic efficacy.

Frequently Asked Questions

Lercanidipine Hcl Viatris contains Lercanidipine Hydrochloride, a calcium channel blocker indicated for the treatment of hypertension. It helps lower elevated systolic and diastolic blood pressure in adult patients, either as monotherapy or in combination with other antihypertensive agents.

Lercanidipine selectively blocks L-type calcium channels in vascular smooth muscle. By reducing calcium entry, it causes arterial vasodilation, which decreases peripheral vascular resistance and leads to a reduction in systemic blood pressure without markedly affecting heart contractility.

The dosage of Lercanidipine Hcl Viatris is individualized by the prescribing healthcare professional. The prescriber determines the appropriate strength and frequency based on the patient’s blood pressure response, age, renal and hepatic function, and any concomitant medications.

Safety of Lercanidipine in pregnancy and lactation has not been established. It should be used only if the potential benefit justifies the potential risk to the fetus or infant. Women who are pregnant, planning pregnancy, or breastfeeding should discuss alternatives with their healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide. After verification of trade or institutional credentials, the sales team will respond with pricing, availability, shipping details and any necessary import documentation.

Lercanidipine belongs to the dihydropyridine calcium‑channel blocker class, offering potent arterial vasodilation with a relatively low incidence of reflex tachycardia. Compared with agents such as amlodipine, Lercanidipine has a longer half‑life and may provide smoother blood‑pressure control, though clinical choice depends on individual patient factors and tolerability.

Store the tablets at ambient temperature, preferably below 25 °C. Keep them in the original blister pack or container to protect from moisture and light. Do not refrigerate or freeze the product, and keep it out of reach of children.

Lercanidipine Hcl Viatris is taken orally as a tablet. It can be swallowed with or without food, although taking it with a meal may reduce the risk of transient flushing. The tablet should be swallowed whole with a glass of water and not chewed or crushed.

Serious adverse events, although rare, include severe hypotension, myocardial infarction, angioedema, hepatic dysfunction, and cardiac conduction disturbances such as heart block. Patients should seek immediate medical attention if they experience sudden dizziness, fainting, chest pain, swelling of the face or throat, or abnormal liver test results.

Lercanidipine is contraindicated in patients with known hypersensitivity to the drug or any component of the formulation, as well as in individuals with severe hypotension, cardiogenic shock, or unstable angina. Caution is also advised for patients with significant hepatic impairment or those taking strong CYP3A4 inhibitors.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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