Product image of Lercanidipine Medreg (Lercanidipine Hydrochloride) supplied by GNH India

Lercanidipine Medreg

Active Ingredient:
Lercanidipine Hydrochloride
Origin:
EU

Lercanidipine Medreg (Lercanidipine Hydrochloride)

Lercanidipine, the active ingredient in Lercanidipine Medreg, is a calcium channel blocker presented as an oral tablet for oral use. It is used to treat hypertension in adult patients.
GNH India supplies Lercanidipine Medreg as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Medreg S.R.O.

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Lercanidipine is a dihydropyridine calcium channel blocker indicated for the management of high blood pressure.

  • Hypertension: lowers elevated systolic and diastolic blood pressure, helping to reduce the risk of cardiovascular complications.

How It Works

  • Lercanidipine selectively blocks L‑type calcium channels in vascular smooth muscle, reducing calcium influx. This inhibition leads to relaxation of arterial smooth muscle, vasodilation, and a consequent decrease in peripheral vascular resistance, which lowers systemic blood pressure.

Side Effects

Lercanidipine may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects

  • Headache: mild to moderate intensity, often transient.
  • Flushing: sensation of warmth and redness, usually resolves without intervention.
  • Peripheral edema: swelling of the ankles or lower legs.
  • Dizziness: especially upon standing quickly.
  • Fatigue: general feeling of tiredness.

Serious or Rare Side Effects

  • Severe hypotension: marked drop in blood pressure that may cause fainting.
  • Myocardial infarction: rare occurrence of heart attack.
  • Hepatic dysfunction: abnormal liver enzyme elevations.
  • Allergic reactions: rash, pruritus, or urticaria.
  • Angioedema: swelling of face, lips, or throat.
  • Cardiac arrhythmia: irregular heart rhythm.

Precautions & Warnings

Before initiating therapy, clinicians should assess patient‑specific factors and monitor for potential risks.

  • Blood pressure monitoring: check regularly to ensure therapeutic response and avoid excessive lowering.
  • Hepatic impairment: use with caution; dose adjustment may be required.
  • Elderly patients: start at the lowest effective dose due to increased sensitivity.
  • Concomitant antihypertensives: monitor for additive hypotensive effects.
  • Known hypersensitivity: discontinue if allergic reaction occurs.
  • Store at room temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Lercanidipine can interact with several drug classes, influencing its efficacy or safety.

Major Interactions (Avoid)

  • Strong CYP3A4 inhibitors (e.g., ketoconazole, itraconazole): may increase plasma concentrations.
  • Grapefruit juice: can markedly raise drug levels.
  • Other potent antihypertensives: risk of additive hypotension.

Moderate Interactions (Monitor Closely):\n- CYP3A4 inducers (e.g., rifampin, carbamazepine): may reduce effectiveness.

  • Diuretics: may enhance electrolyte disturbances.
  • NSAIDs: can attenuate antihypertensive response.

Frequently Asked Questions

Lercanidipine Medreg contains the active ingredient lercanidipine, which is prescribed to lower elevated blood pressure in adults with hypertension. By reducing systemic vascular resistance, it helps control hypertension and lowers the risk of cardiovascular events.

Lercanidipine selectively blocks L‑type calcium channels in arterial smooth muscle. This inhibition prevents calcium entry, causing the muscles to relax, leading to vasodilation and a reduction in peripheral resistance, which ultimately lowers blood pressure.

The appropriate dose of Lercanidipine Medreg is determined by the prescribing healthcare professional based on the patient’s clinical condition, response to therapy, and any concomitant medications. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

The safety of lercanidipine in pregnancy and lactation has not been established. It should only be used if the potential benefit justifies the potential risk to the fetus or infant, and this decision must be made by a qualified healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Lercanidipine belongs to the dihydropyridine calcium‑channel blocker class, which primarily causes arterial vasodilation. Compared with ACE inhibitors or beta‑blockers, it may have a lower incidence of cough but can cause peripheral edema more frequently. Choice of therapy depends on patient profile and comorbidities.

Lercanidipine Medreg tablets should be stored at room temperature, below 25 °C, in the original packaging to protect from moisture and light. Keep the product out of reach of children and do not use after the expiry date.

Lercanidipine Medreg is taken orally, usually once daily, with or without food, as directed by the prescriber. Swallow the tablet whole with a glass of water and do not crush or chew it.

Serious adverse events, although rare, include severe hypotension, myocardial infarction, hepatic dysfunction, allergic reactions such as angioedema, and cardiac arrhythmias. Patients should seek immediate medical attention if they experience symptoms like fainting, chest pain, severe rash, or swelling of the face or throat.

Lercanidipine Medreg is contraindicated in patients with known hypersensitivity to lercanidipine or any component of the formulation. Caution is advised in individuals with severe hepatic impairment, unstable angina, or those taking strong CYP3A4 inhibitors.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.