Product image of Lercanidipino Tecnigen (Lercanidipine Hydrochloride) supplied by GNH India

Lercanidipino Tecnigen

Active Ingredient:
Lercanidipine Hydrochloride
Origin:
EU

Lercanidipino Tecnigen (Lercanidipine Hydrochloride)

Lercanidipine, the active ingredient in Lercanidipino Tecnigen, is a calcium channel blocker presented as an oral tablet for oral use. It is indicated for the treatment of hypertension in adult patients.
GNH India supplies Lercanidipino Tecnigen as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Tecnimede España Ind. Fca., S.A.

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Indications & Clinical Uses

Lercanidipine is used to manage high blood pressure by acting on the vascular smooth‑muscle calcium channels.

  • Hypertension: lowers systolic and diastolic pressure through vasodilation.
  • Essential hypertension: provides sustained blood‑pressure control in primary hypertension.
  • Isolated systolic hypertension: reduces elevated systolic readings in older adults.

How It Works

  • Lercanidipine inhibits L‑type calcium channels in vascular smooth‑muscle cells, decreasing calcium influx. This relaxation of arterial smooth muscle leads to vasodilation, reduced peripheral resistance, and consequently lower arterial blood pressure without significant negative inotropic effects.

Side Effects

Adverse reactions may occur with any antihypertensive therapy.

Common Side Effects

  • Headache: mild to moderate intensity, often transient.
  • Flushing: warmth and redness, typically resolves with continued use.
  • Peripheral edema: swelling of ankles or feet, especially in the lower limbs.
  • Dizziness: sensation of light‑headedness, usually related to blood‑pressure changes.

Serious or Rare Side Effects

  • Severe hypotension: marked drop in blood pressure requiring medical attention.
  • Angioedema: swelling of face, lips, tongue or throat that may compromise airway.

Precautions & Warnings

Before initiating therapy, clinicians should consider several safety aspects.

  • Blood pressure monitoring: ensure target levels are achieved without excessive drop.
  • Hepatic function assessment: use with caution in patients with liver impairment.
  • Elderly patients: start at lower doses and monitor for orthostatic effects.
  • Concomitant antihypertensives: avoid additive hypotensive reactions.
  • Store at room temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Lercanidipine can interact with other medicines, altering its efficacy or safety.

Major Interactions (Avoid)

  • Strong CYP3A4 inhibitors (e.g., ketoconazole, itraconazole): may increase plasma levels.
  • Grapefruit juice: can raise systemic exposure and risk of hypotension.
  • Rifampicin: induces metabolism, reducing therapeutic effect.

Moderate Interactions (Monitor Closely):\n- Beta‑blockers: additive blood‑pressure lowering effect.

  • Diuretics: may enhance volume depletion and orthostatic symptoms.

Frequently Asked Questions

Lercanidipino Tecnigen contains lercanidipine, which is prescribed to lower high blood pressure in adults. By relaxing the smooth muscle of blood vessels, it helps achieve and maintain target blood‑pressure levels, reducing the risk of cardiovascular complications associated with hypertension.

Lercanidipine blocks L‑type calcium channels on vascular smooth‑muscle cells, preventing calcium entry that is required for muscle contraction. This inhibition causes the arteries to dilate, decreasing peripheral resistance and consequently lowering systemic arterial pressure.

The appropriate dose of lercanidipine is determined by the prescribing clinician based on the patient’s blood‑pressure profile, age, renal and hepatic function, and concomitant medications. Dosage adjustments are individualized and should follow the prescriber’s instructions.

Safety data for lercanidipine in pregnancy and lactation are limited. It should only be used if the potential benefit justifies the potential risk to the fetus or infant, and the decision must be made by a qualified healthcare professional.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Both lercanidipine and amlodipine belong to the dihydropyridine class of calcium‑channel blockers and lower blood pressure by vasodilation. Lercanidipine has a longer half‑life and may provide smoother blood‑pressure control with a lower incidence of certain side effects such as peripheral edema, though individual response varies.

Lercanidipino Tecnigen should be stored at room temperature, below 25 °C, in the original packaging to protect it from moisture and light. Keep the product out of reach of children and do not use it after the expiry date.

The medication is taken orally, usually once daily, with or without food, as directed by the prescribing physician. Swallow the tablet whole with a glass of water; do not crush or chew it unless specifically instructed.

Serious adverse events, though rare, include severe hypotension, angioedema, and myocardial infarction. Patients should seek immediate medical attention if they experience sudden swelling of the face or throat, a rapid drop in blood pressure, or chest pain.

Lercanidipine is contraindicated in patients with known hypersensitivity to the drug or any component of the formulation. It should also be avoided in individuals with severe aortic stenosis or uncontrolled heart failure unless specifically advised by a cardiologist.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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