Product image of Lercapin (Lercanidipine Hydrochloride) supplied by GNH India

Lercapin

Active Ingredient:
Lercanidipine Hydrochloride
Origin:
EU

Lercapin (Lercanidipine Hydrochloride)

Lercanidipine Hydrochloride, the active ingredient in Lercapin, is a calcium channel blocker presented as an oral tablet for oral use. It is indicated for the treatment of hypertension in adult patients. Lercapin works by relaxing vascular smooth muscle, thereby lowering systemic blood pressure.

GNH India supplies Lercapin as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Menarini International Operations Luxembourg S.A.

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

  • Lercapin, a calcium channel blocker, is employed in the management of elevated blood pressure conditions.
  • Essential hypertension: reduces systemic vascular resistance to achieve target blood pressure.
  • Primary hypertension: provides sustained blood pressure control.
  • Isolated systolic hypertension: lowers systolic pressure while maintaining diastolic stability.

How It Works

  • Lercanidipine Hydrochloride selectively inhibits L‑type calcium channels in vascular smooth muscle cells. This blockade reduces calcium influx, leading to relaxation of arterial smooth muscle, vasodilation, and a consequent decrease in peripheral vascular resistance, which lowers arterial blood pressure.

Side Effects

Lercapin may cause a range of adverse reactions.

Common Side Effects

  • Headache: mild to moderate intensity.
  • Flushing: transient warmth and redness of the skin.
  • Peripheral edema: swelling of ankles or feet.
  • Dizziness: sensation of light‑headedness, especially after standing.
  • Tachycardia: increased heart rate.
  • Nausea: mild gastrointestinal discomfort.

Serious or Rare Side Effects

  • Severe hypotension: marked drop in blood pressure requiring medical attention.
  • Angioedema: swelling of face, lips, or throat.
  • Hepatic dysfunction: elevated liver enzymes or jaundice.
  • Allergic reactions: rash, itching, or anaphylaxis.
  • Myocardial infarction: rare occurrence of heart attack.
  • Arrhythmia: irregular heart rhythm.

Precautions & Warnings

Before initiating therapy, certain precautions should be observed.

  • Blood pressure monitoring: assess baseline and follow‑up readings.
  • Gradual dose adjustment: avoid abrupt changes to prevent hypotension.
  • Hepatic impairment: use with caution; dose may need adjustment.
  • Elderly patients: monitor for increased sensitivity to side effects.
  • Concomitant CYP3A4 inhibitors: evaluate for potential drug accumulation.
  • Pregnancy: only if benefits outweigh risks; consult a physician.
  • Store at ambient temperature: keep below 25 °C in the original container, protect from moisture.

Avoid Interactions

Lercapin can interact with several drug classes.

Major Interactions (Avoid)

  • Strong CYP3A4 inhibitors (e.g., ketoconazole): may increase plasma concentrations.
  • Concurrent use with other antihypertensives: additive hypotensive effect.
  • Grapefruit juice: can elevate drug levels.

Moderate Interactions (Monitor Closely):\n- Diuretics: may enhance diuretic‑induced electrolyte shifts.

  • Beta‑blockers: risk of excessive bradycardia.
  • Lithium: possible increase in lithium serum levels.

Frequently Asked Questions

Lercapin contains the active ingredient Lercanidipine Hydrochloride, which is prescribed for the treatment of hypertension. It helps lower elevated blood pressure by relaxing arterial smooth muscle, thereby reducing vascular resistance and improving cardiovascular health.

Lercanidipine selectively blocks L‑type calcium channels in vascular smooth muscle cells. This inhibition reduces calcium entry, causing the muscles to relax, leading to vasodilation and a subsequent decrease in peripheral vascular resistance, which lowers systemic blood pressure.

The appropriate dose of Lercapin is determined by the prescribing healthcare professional based on the individual’s blood pressure, response to therapy, and overall medical condition. Dosage adjustments are made to achieve optimal blood pressure control while minimizing side effects.

Safety of Lercapin during pregnancy or lactation has not been definitively established. It should only be used if the potential benefit justifies the potential risk to the fetus or infant, and this decision must be made in consultation with a qualified healthcare provider.

To order Lercapin, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and necessary import documentation.

Both Lercapin (Lercanidipine) and amlodipine belong to the dihydropyridine class of calcium channel blockers and are used to treat hypertension. Lercanidipine has a longer half‑life and may offer smoother blood pressure control with a lower incidence of certain side effects such as peripheral edema.

Lercapin should be stored at ambient temperature, preferably below 25 °C. Keep the tablets in the original packaging, protect them from moisture and direct sunlight, and ensure they are out of reach of children.

Lercapin is taken orally, usually once daily, with or without food. The tablet should be swallowed whole with a glass of water, and patients should follow the dosing schedule prescribed by their healthcare professional.

Serious risks include severe hypotension, angioedema, hepatic dysfunction, and rare allergic reactions such as anaphylaxis. Patients should seek immediate medical attention if they experience symptoms like sudden dizziness, swelling of the face or throat, or signs of liver injury.

Lercapin should not be used by individuals with known hypersensitivity to Lercanidipine or any component of the formulation, patients with severe hepatic impairment, or those taking contraindicated medications that may cause dangerous drug interactions.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Related Products

Other formulations containing Lercanidipine Hydrochloride

A

A
A

A
A

A
A

A

Browse all products →

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Regulatory recognitions

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.

SGS GSDP Certification

GSDP Compliant from SGS

URS ISO 9001

URS ISO 9001 Certification

FDA Maharashtra

Licensed by FDA Maharashtra

IEC License DGFT

IEC License issued by DGFT