Product image of Lescol L.P. (Fluvastatin Sodium) supplied by GNH India

Lescol L.P.

Active Ingredient:
Fluvastatin Sodium
Origin:
EU

Lescol L.P. (Fluvastatin Sodium)

Fluvastatin Sodium, the active ingredient in Lescol L.P., is a HMG‑CoA reductase inhibitor presented as an oral tablet for oral use. It lowers elevated LDL cholesterol and is indicated for adult patients with hypercholesterolemia to reduce cardiovascular risk.

GNH India supplies Lescol L.P. as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides reliable, on‑time delivery to meet global healthcare needs. Our distribution network spans Europe, Asia, Africa and the Americas, ensuring consistent product availability across diverse markets.

Manufacturer / TM Owner

Ethyx Pharmaceuticals

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Indications & Clinical Uses

  • Fluvastatin Sodium is a statin medication used to manage disorders of lipid metabolism.
  • Hypercholesterolemia: reduces LDL cholesterol levels, helping achieve target lipid profiles.
  • Primary prevention of cardiovascular disease: lowers risk of myocardial infarction and stroke in patients with elevated LDL.
  • Secondary prevention of cardiovascular disease: decreases recurrence of cardiovascular events in patients with established atherosclerotic disease.

How It Works

  • Fluvastatin sodium competitively inhibits HMG‑CoA reductase, the key enzyme in hepatic cholesterol biosynthesis. This inhibition reduces intracellular cholesterol, leading to up‑regulation of LDL receptors on hepatocyte surfaces and increased clearance of LDL particles from the circulation, thereby lowering plasma LDL concentrations.

Side Effects

Fluvastatin sodium may cause a range of adverse reactions.

Common Side Effects

  • Headache
  • Gastrointestinal discomfort (nausea, abdominal pain)
  • Myalgia or muscle aches
  • Elevated liver enzymes
  • Dizziness
  • Fatigue

Serious or Rare Side Effects

  • Rhabdomyolysis
  • Severe hepatic injury
  • Allergic reactions (rash, angioedema)
  • Myopathy with marked CK elevation
  • Hepatitis
  • Pancreatitis

Precautions & Warnings

  • When prescribing fluvastatin, clinicians should consider several safety measures.
  • Monitor liver function tests: assess baseline transaminases and repeat periodically.
  • Assess renal function: dose adjustment may be needed in renal impairment.
  • Evaluate for drug interactions: avoid concomitant strong CYP3A4 inhibitors.
  • Use caution in hypothyroidism: increased risk of myopathy.
  • Avoid in active liver disease: contraindicated with significant hepatic dysfunction.
  • Store below 25°C: keep in the original pack, protect from moisture.

Avoid Interactions

Fluvastatin can interact with other medicines, requiring attention to avoid adverse outcomes.

Major Interactions (Avoid)

  • Strong CYP3A4 inhibitors (e.g., itraconazole, clarithromycin)
  • Gemfibrozil
  • Cyclosporine
  • High‑dose niacin
  • Certain macrolide antibiotics

Moderate Interactions (Monitor Closely)

  • Amlodipine
  • Digoxin
  • Warfarin
  • Beta‑blockers
  • Antacids (may affect absorption)

Frequently Asked Questions

Lescol L.P. contains fluvastatin sodium, a statin medication prescribed to lower elevated LDL cholesterol in patients with hypercholesterolemia and to reduce the risk of cardiovascular events such as heart attack and stroke.

Fluvastatin sodium inhibits the enzyme HMG‑CoA reductase, the rate‑limiting step in hepatic cholesterol synthesis. This decreases intracellular cholesterol, up‑regulates LDL receptors, and enhances clearance of LDL particles from the bloodstream.

The dosage of Lescol L.P. is individualized by the prescribing healthcare professional based on the patient’s cholesterol levels, cardiovascular risk profile, age, renal and hepatic function, and concomitant medications. Patients should follow the prescriber’s instructions.

Safety of fluvastatin during pregnancy or lactation has not been established. It is generally contraindicated in pregnancy and should be used only if the potential benefit justifies the potential risk to the fetus. Breastfeeding mothers should consult their physician.

To place an order, submit an enquiry on the Lescol L.P. product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and required import documentation.

Lescol L.P. (fluvastatin) is a moderate‑intensity statin with a relatively favorable drug‑interaction profile compared with some higher‑potency statins such as atorvastatin or rosuvastatin. Choice of statin depends on the target LDL reduction, patient tolerance, comorbidities and potential interactions.

Lescol L.P. tablets should be stored at temperatures below 25 °C, in the original packaging, protected from moisture and direct sunlight. Do not store in bathrooms or near heat sources.

Lescol L.P. is taken orally, usually once daily with or without food, as directed by the prescribing clinician. Swallow the tablet whole with a glass of water; do not crush or chew unless specifically instructed.

The most serious adverse reactions include rhabdomyolysis, severe liver injury, and hypersensitivity reactions such as Stevens‑Johnson syndrome. Patients should report unexplained muscle pain, weakness, dark urine, or jaundice promptly to their healthcare provider.

Lescol L.P. should be avoided in patients with active liver disease, unexplained persistent elevations of hepatic transaminases, known hypersensitivity to fluvastatin or any excipients, and in pregnant women unless clearly indicated. Caution is also advised in severe renal impairment.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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