Lestedon (Dutasteride)

Dutasteride blocks both type I and type II 5‑alpha‑reductase enzymes, the proteins responsible for converting testosterone into dihydrotestosterone (DHT). Reduced DHT limits androgen‑driven prostate cell growth, leading to a gradual decrease in prostate size and relief of urinary obstruction associated with BPH.

The dosage of Lestedon is determined by the prescribing physician based on the individual’s clinical condition, age, and response to therapy. Healthcare providers follow approved labeling and clinical guidelines to select the appropriate strength and dosing schedule for each patient.

Dutasteride is classified as pregnancy category X because it can cause fetal abnormalities, especially related to male genital development. It is therefore contraindicated in pregnant women. The drug is also excreted in breast milk, so breastfeeding is not recommended while taking Lestedon.

To place an order, submit an enquiry on the Lestedon product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and the necessary import documentation.

The primary alternative to dutasteride is finasteride, another 5‑alpha‑reductase inhibitor that selectively blocks only the type II enzyme. Dutasteride inhibits both type I and II isoforms, offering a more complete reduction of DHT. Clinical studies suggest dutasteride may achieve greater prostate volume reduction, though individual response and safety profiles should guide therapy choice.

Lestedon tablets should be stored at ambient temperature, preferably below 25 °C. Keep the product in its original packaging to protect it from moisture and light. Do not store in areas with high humidity or extreme heat, and keep out of reach of children.

Lestedon is taken orally as a tablet. Swallow the tablet whole with a glass of water; it may be taken with or without food. Patients should follow the dosing schedule prescribed by their healthcare professional and should not split, crush, or chew the tablet unless directed to do so.

Serious adverse events include severe allergic reactions such as rash, angioedema or anaphylaxis, significant liver enzyme elevations indicating possible hepatic injury, and testicular pain. Patients should seek immediate medical attention if they experience any signs of an allergic reaction, persistent jaundice, or unexplained testicular discomfort.

Lestedon is contraindicated in women, especially those who are pregnant or may become pregnant, due to the risk of fetal harm. Men with known hypersensitivity to dutasteride or any component of the formulation should avoid it. Additionally, patients with active prostate cancer or those receiving certain hormonal therapies should not use Lestedon without specialist guidance.