Product image of Leticia (Desogestrel, Ethinylestradiol) supplied by GNH India

Leticia

Active Ingredient:
Desogestrel, Ethinylestradiol
Origin:
EU

Leticia (Desogestrel, Ethinylestradiol)

Desogestrel/Ethinylestradiol, the active ingredients in Leticia, are a combined oral contraceptive presented as an oral tablet for oral use. They are prescribed to prevent pregnancy and to help regulate the menstrual cycle in women of reproductive age.

GNH India supplies Leticia as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Gedeon Richter Plc.

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Indications & Clinical Uses

Leticia, a combined estrogen‑progestin oral contraceptive, acts on the hypothalamic‑pituitary‑ovarian axis to prevent pregnancy and stabilize menstrual bleeding.

  • Prevention of pregnancy: provides reliable contraceptive protection when taken as directed.
  • Menstrual cycle regulation: helps achieve more predictable bleeding patterns and reduces dysmenorrhea.

How It Works

  • Desogestrel/Ethinylestradiol suppresses the hypothalamic‑pituitary‑ovarian axis, lowering LH and FSH secretion to inhibit ovulation. The estrogen component stabilises the endometrium, while the progestin thickens cervical mucus and induces endometrial changes that together prevent fertilisation and implantation.

Side Effects

Leticia may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects

  • Nausea: mild stomach upset that often resolves with continued use.
  • Breast tenderness: temporary swelling or discomfort.
  • Headache: mild to moderate intensity.
  • Spotting or breakthrough bleeding: irregular bleeding between periods.
  • Mood changes: irritability or mild depressive symptoms.
  • Weight fluctuation: slight increase or decrease.

Serious or Rare Side Effects

  • Thromboembolic events: deep‑vein thrombosis or pulmonary embolism.
  • Hypertension: significant rise in blood pressure.
  • Liver disorders: cholestatic jaundice or hepatic adenoma.
  • Severe allergic reaction: rash, swelling, or anaphylaxis.
  • Visual disturbances: sudden loss of vision or blurred sight.

Precautions & Warnings

Before prescribing Leticia, clinicians should evaluate individual risk factors and counsel patients on safe use.

  • Contraindicated in pregnancy: product is classified as pregnancy category X and must not be used.
  • Avoid in smokers over 35 years: increased risk of cardiovascular events.
  • Screen for history of thromboembolic disorders: use only if benefits outweigh risks.
  • Monitor blood pressure regularly: combined estrogen‑progestin can elevate BP.
  • Store at ambient temperature: keep below 25°C, retain in original packaging, protect from moisture.

Avoid Interactions

Leticia can interact with several medication classes, altering its efficacy or safety profile.

Major Interactions (Avoid)

  • Antiepileptic enzyme inducers (e.g., carbamazepine, phenytoin): reduce contraceptive efficacy.
  • Antiretroviral protease inhibitors (e.g., ritonavir): may increase hormone levels, raising side‑effect risk.
  • St. John’s wort: decreases hormone levels, increasing chance of unintended pregnancy.

Moderate Interactions (Monitor Closely)

  • Antibiotics such as rifampin: may lower effectiveness; consider backup contraception.
  • SSRIs (e.g., fluoxetine): may heighten mood‑related side effects.
  • Diuretics (e.g., thiazides): may affect fluid balance and blood pressure, requiring monitoring.

Frequently Asked Questions

Leticia is a combined oral contraceptive containing desogestrel and ethinylestradiol. It is prescribed to prevent pregnancy and to help regulate menstrual cycles in women of reproductive age, providing reliable birth control when taken as directed.

The combination suppresses the hypothalamic‑pituitary‑ovarian axis, lowering luteinising hormone and follicle‑stimulating hormone release, which prevents ovulation. Ethinylestradiol stabilises the endometrium, while desogestrel thickens cervical mucus and alters the uterine lining, together blocking fertilisation and implantation.

The dosing regimen for Leticia is determined by the prescribing clinician. Typically, it is taken once daily at the same time for a 21‑day active phase followed by a hormone‑free interval, but the exact schedule must be individualized and confirmed by a healthcare professional.

Leticia is classified as pregnancy category X, meaning it must not be used during pregnancy because it can harm the fetus. It is also not recommended while breastfeeding, as hormonal exposure may affect milk production and infant health. Alternative methods should be considered.

To order Leticia, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Leticia contains desogestrel, a third‑generation progestin, which is associated with a lower incidence of androgenic side effects compared with earlier progestins. Its estrogen component, ethinylestradiol, is standard across most combined pills, offering comparable contraceptive efficacy while differing mainly in tolerability profiles.

Leticia tablets should be stored at ambient temperature, below 25 °C, in their original blister pack to protect from moisture and light. Keep the medication out of reach of children and do not use after the expiry date printed on the packaging.

Leticia is taken orally, usually one tablet each day at the same time. A typical cycle consists of 21 consecutive active tablets followed by a 7‑day hormone‑free interval, during which withdrawal bleeding occurs. Patients should follow the prescribing clinician’s instructions for missed doses.

Serious risks include venous thromboembolism, arterial thrombosis, hypertension, severe liver disease, and rare allergic reactions such as anaphylaxis. Women with a history of clotting disorders, smoking over age 35, or certain cardiovascular conditions should be evaluated carefully before use.

Leticia is contraindicated in women who are pregnant, have known or suspected estrogen‑dependent tumors, active liver disease, uncontrolled hypertension, a history of thromboembolic events, or who are smokers over 35 years of age. It should also be avoided in individuals with known hypersensitivity to any component of the tablet.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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