Product image of Letrozol Medical Valley (Letrozole) supplied by GNH India

Letrozol Medical Valley

Active Ingredient:
Letrozole
Origin:
EU

Letrozol Medical Valley (Letrozole)

Letrozole, the active ingredient in Letrozol Medical Valley, is an aromatase inhibitor presented as an oral tablet for oral use. The medication belongs to the antineoplastic hormone‑therapy class and works by reducing estrogen synthesis, thereby limiting the growth of hormone‑dependent breast tumours in postmenopausal women.

GNH India supplies Letrozol Medical Valley as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, oncology centres, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Medical Valley Invest Ab

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Letrozol Medical Valley, an aromatase inhibitor, is indicated for conditions driven by estrogen production.

  • Hormone receptor‑positive breast cancer (postmenopausal women): slows disease progression and reduces recurrence risk.
  • Adjuvant therapy after surgery: helps prevent cancer return when used in combination with other agents.
  • Neoadjuvant therapy before surgery: may shrink tumours to facilitate breast‑conserving procedures.

How It Works

  • Letrozole selectively and non‑competitively inhibits the aromatase enzyme, which converts androgens to estrogens in peripheral tissues. By blocking this conversion, circulating estrogen levels fall, depriving estrogen‑dependent breast cancer cells of a key growth stimulus and thereby inhibiting tumour proliferation.

Side Effects

Letrozol Medical Valley may cause a range of adverse reactions.

Common Side Effects

  • Hot flashes: transient feeling of warmth and sweating.
  • Joint or muscle pain: mild to moderate musculoskeletal discomfort.
  • Fatigue: reduced energy or tiredness.
  • Nausea: occasional upset stomach.
  • Headache: mild to moderate cranial pain.
  • Increased cholesterol: modest rise in blood lipid levels.

Serious or Rare Side Effects

  • Osteoporosis or bone fractures: decreased bone mineral density.
  • Severe liver injury: marked elevation of hepatic enzymes.
  • Deep vein thrombosis or pulmonary embolism: clot formation in veins.
  • Allergic reactions: rash, itching, swelling, or anaphylaxis.
  • Cardiovascular events: hypertension or heart failure.
  • Vision changes: blurred vision or ocular discomfort.

Precautions & Warnings

When using Letrozol Medical Valley, consider the following safety measures.

  • Pregnancy avoidance: contraindicated in pregnancy (Category X); ensure effective contraception.
  • Menopause status: only indicated for postmenopausal patients; assess menopausal criteria before initiation.
  • Bone health monitoring: perform baseline and periodic bone density scans.
  • Liver function assessment: check hepatic enzymes prior to treatment and monitor regularly.
  • Drug interactions: review concomitant medications for potential CYP450 interactions.
  • Store at ambient temperature: keep below 25 °C, retain in original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Letrozol Medical Valley can interact with several drug classes.

Major Interactions (Avoid)

  • Strong CYP3A4 inducers (e.g., rifampin, carbamazepine): may markedly reduce letrozole exposure.
  • Estrogen‑containing therapies (hormone replacement, oral contraceptives): antagonize therapeutic effect.

Moderate Interactions (Monitor Closely)

  • CYP2A6 inhibitors (e.g., fluvoxamine): may increase plasma concentrations.
  • Anticoagulants (warfarin): monitor INR as letrozole may affect clotting parameters.
  • Lipid‑lowering agents (statins): observe for altered lipid profiles.
  • Antidepressants (SSRIs): assess for additive fatigue or mood changes.

Frequently Asked Questions

Letrozol Medical Valley contains letrozole, an aromatase inhibitor that is used to treat hormone receptor‑positive breast cancer in postmenopausal women. It works by lowering estrogen levels, which helps slow tumour growth and reduce the risk of cancer recurrence.

Letrozole blocks the aromatase enzyme, preventing the conversion of androgens to estrogen in peripheral tissues. The resulting drop in circulating estrogen deprives estrogen‑dependent breast cancer cells of a key growth signal, thereby inhibiting tumour proliferation.

The specific dose and dosing schedule are determined by the prescribing clinician based on the patient’s medical condition, renal and hepatic function, and other individual factors. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

Letrozole is classified as Pregnancy Category X, meaning it is contraindicated in pregnancy because it can cause fetal harm. It is also not recommended while breastfeeding, as it may pass into breast milk and affect the infant. Effective contraception is required for women of child‑bearing potential.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and the necessary import documentation.

Letrozole is a third‑generation, non‑steroidal aromatase inhibitor with a high potency and a long half‑life, offering once‑daily dosing. Compared with earlier agents such as anastrozole or exemestane, letrozole often provides greater estrogen suppression, which can translate into improved disease‑free survival in certain clinical settings.

Letrozol Medical Valley tablets should be stored at ambient temperature, below 25 °C, in the original blister pack or bottle. Keep the product away from moisture, direct sunlight and heat sources to maintain stability and potency.

The medication is taken orally, usually as a whole tablet with water. It is generally prescribed for once‑daily intake, but the exact timing (e.g., with or without food) should follow the prescriber’s guidance.

Serious adverse events include osteoporosis or bone fractures, severe liver injury, deep‑vein thrombosis or pulmonary embolism, and rare allergic reactions such as anaphylaxis. Patients should be monitored regularly for bone health, liver function and signs of clotting disorders.

Letrozole is contraindicated in pregnant women, premenopausal patients, and individuals with known hypersensitivity to letrozole or any component of the formulation. It should also be avoided in patients with severe liver impairment or uncontrolled osteoporosis without appropriate medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Related Products

Other formulations containing Letrozole

A

A
A

A
A

A
A

A

Browse all products →

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Regulatory recognitions

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.

SGS GSDP Certification

GSDP Compliant from SGS

URS ISO 9001

URS ISO 9001 Certification

FDA Maharashtra

Licensed by FDA Maharashtra

IEC License DGFT

IEC License issued by DGFT