Product image of Letrozole Teva (Letrozole) supplied by GNH India

Letrozole Teva

Active Ingredient:
Letrozole
Origin:
EU

Letrozole Teva (Letrozole)

Letrozole, the active ingredient in Letrozole Teva, is an aromatase inhibitor presented as a tablet for oral use. It is used to treat hormone‑receptor positive breast cancer in postmenopausal women. GNH India supplies Letrozole Teva as a licensed, GDP‑compliant international pharmaceutical supplier serving oncology centres worldwide.

Manufacturer / TM Owner

Teva Pharma B.V.

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Letrozole is an aromatase inhibitor indicated for hormone‑receptor positive breast cancer in postmenopausal women.

  • Early‑stage breast cancer: reduces risk of recurrence after surgery.
  • Advanced/metastatic breast cancer: slows disease progression and improves survival.
  • Adjuvant therapy after tumor removal: helps prevent cancer return.

How It Works

  • Letrozole selectively inhibits the aromatase enzyme, which converts adrenal and ovarian androgens into estrogens. By blocking this peripheral conversion, systemic estrogen levels decline, limiting the growth stimulus for estrogen‑dependent tumor cells in hormone‑receptor positive breast cancer.

Side Effects

Letrozole may cause a range of adverse reactions.

Common Side Effects

  • Hot flashes: transient episodes of increased warmth.
  • Arthralgia: joint pain or stiffness.
  • Fatigue: persistent tiredness.
  • Nausea: mild to moderate upset stomach.
  • Headache: occasional throbbing pain.
  • Osteoporosis: reduced bone mineral density.

Serious or Rare Side Effects

  • Venous thromboembolism: blood clots in deep veins.
  • Severe liver injury: marked elevation of hepatic enzymes.
  • Cardiac arrhythmia: irregular heart rhythm.
  • Severe allergic reaction: rash, swelling, or breathing difficulty.
  • Hyperglycemia: significant rise in blood glucose levels.

Precautions & Warnings

Before initiating Letrozole therapy, consider the following precautions.

  • Bone health assessment: evaluate risk of osteoporosis and consider calcium/vitamin D supplementation.
  • Liver function monitoring: check baseline enzymes and repeat periodically.
  • Cardiovascular risk evaluation: assess history of thromboembolic events.
  • Drug interactions review: avoid concomitant use of strong CYP2A6 inhibitors.
  • Pregnancy and lactation: contraindicated; ensure effective contraception.
  • Store at ambient temperature: keep below 25 °C, retain in original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Letrozole can interact with several medicines; monitoring is essential.

Major Interactions (Avoid)

  • Strong CYP2A6 inhibitors (e.g., fluvoxamine): may increase letrozole exposure.
  • Estrogen‑containing therapies (e.g., hormone replacement): antagonize therapeutic effect.

Moderate Interactions (Monitor Closely)

  • Anticoagulants (e.g., warfarin): may alter coagulation parameters.
  • CYP3A4 inducers (e.g., rifampin): may reduce letrozole plasma levels.
  • Tamoxifen: concurrent use may affect efficacy of both agents.

Frequently Asked Questions

Letrozole Teva is used to treat hormone‑receptor positive breast cancer in postmenopausal women. It works as part of adjuvant therapy after surgery or for advanced disease to slow tumor growth by lowering estrogen levels.

Letrozole blocks the aromatase enzyme, which normally converts androgens into estrogens. By inhibiting this conversion, systemic estrogen concentrations fall, depriving estrogen‑dependent breast cancer cells of a key growth signal.

The specific dose of Letrozole Teva is determined by the prescribing clinician based on the patient’s condition, treatment stage, and clinical guidelines. Patients should follow the dose prescribed by their oncologist.

Letrozole is contraindicated in pregnancy and is not recommended for breastfeeding women because it can affect fetal development and pass into breast milk. Effective contraception is required for women of child‑bearing potential.

To order Letrozole Teva, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and necessary import documentation.

Letrozole is a third‑generation aromatase inhibitor with a high potency and longer half‑life compared with earlier agents such as anastrozole. Clinical studies show comparable efficacy, but individual patient tolerance and side‑effect profiles guide the choice of agent.

Letrozole Teva tablets should be stored at ambient temperature, below 25 °C, in the original container to protect them from moisture and light. Do not store in a humid environment or expose to excessive heat.

Letrozole Teva is taken orally, usually once daily, with or without food. The tablet should be swallowed whole with water and not chewed or crushed to ensure proper absorption.

Serious risks include severe liver injury, venous thromboembolism, significant bone loss leading to fractures, and rare allergic reactions. Patients should be monitored regularly for liver function, bone density, and signs of clotting disorders.

Letrozole is not recommended for premenopausal women, pregnant or nursing individuals, patients with severe liver impairment, or those with a history of hypersensitivity to letrozole or its excipients.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Related Products

Other formulations containing Letrozole

A

A
A

A
A

A
A

A

Browse all products →

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Regulatory recognitions

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.

SGS GSDP Certification

GSDP Compliant from SGS

URS ISO 9001

URS ISO 9001 Certification

FDA Maharashtra

Licensed by FDA Maharashtra

IEC License DGFT

IEC License issued by DGFT