Leucovorin 100mg (Leucovorin Calcium Vials) 100mg/10ml

Leucovorin 100mg is a folate analog used to reduce toxic effects of folate antagonists like methotrexate. Available in 100mg/10ml vials for injection. Store between 2-8°C to maintain potency. Ideal for supportive care in chemotherapy regimens.

Strength

100mg/10ml

Pack Size

Storage

2-8°

Manufacturer / TM Owner

Bruck Pharma Pvt Ltd

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Pack/s

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Indications & Clinical Uses

Leucovorin 100mg is primarily used to counteract the effects of folate antagonists such as methotrexate in high-dose chemotherapy. It is also employed to treat megaloblastic anemia caused by folate deficiency when oral therapy is not feasible. The medication supports normal cell function during cytotoxic treatment. It may be used in rescue therapy after methotrexate administration.

Side Effects

Leucovorin 100mg helps restore folate levels in the body, supporting healthy cell production and function. It may reduce side effects associated with folate antagonist toxicity, such as nausea or bone marrow suppression. Users often report improved tolerance to chemotherapy when leucovorin is administered as directed.

Precautions & Warnings

Store leucovorin vials between 2-8°C and protect from light. Avoid freezing or exposure to extreme temperatures. Use only as prescribed by a healthcare professional. Discard any unused solution properly according to local guidelines. Keep out of reach of children and pets.

Avoid Interactions

Leucovorin may interact with other folate antagonists or medications affecting folate metabolism. Combining it with certain anticonvulsants or sulfonamides could alter effectiveness. Alcohol may reduce absorption of folate, potentially diminishing leucovorin's benefits. Always inform your healthcare provider about all medications being taken.

Frequently Asked Questions

Leucovorin 100mg is used to reduce toxic effects of folate antagonists like methotrexate and to treat folate deficiency-related anemia.

Store leucovorin 100mg vials between 2-8°C and protect from light. Do not freeze.

Consult a healthcare provider before combining leucovorin with other medications, as interactions may occur.

Leucovorin is often used during chemotherapy to reduce side effects, but it should only be taken under medical supervision.

Common effects may include nausea or allergic reactions; report any unusual symptoms to a healthcare provider.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated: 29 Jul 2026

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