Product image of Leukast (Montelukast) supplied by GNH India

Leukast

Active Ingredient:
Montelukast
Origin:
EU

Leukast (Montelukast)

Montelukast, the active ingredient in Leukast, is a leukotriene receptor antagonist presented as an oral tablet for oral use. It treats asthma, exercise‑induced bronchoconstriction and allergic rhinitis in adults and children.

GNH India supplies Leukast as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Konpharma S.R.L.

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Leukast (montelukast) is indicated for conditions involving leukotriene‑mediated airway inflammation.

  • Asthma: improves control of persistent asthma and reduces frequency of exacerbations.
  • Exercise‑induced bronchoconstriction: prevents narrowing of airways during physical activity.
  • Allergic rhinitis: relieves nasal congestion, sneezing and itching associated with seasonal allergies.

How It Works

  • Montelukast selectively blocks the cysteinyl leukotriene receptor CysLT1, preventing leukotriene D4 from binding. This inhibition reduces leukotriene‑mediated bronchoconstriction, vascular permeability, and inflammatory cell recruitment in the airways, thereby improving respiratory function and decreasing allergic inflammation.

Side Effects

Leukast may cause a range of adverse reactions, from mild to serious.

Common Side Effects

  • Headache: mild to moderate headache.
  • Upper respiratory infection: symptoms such as sore throat or nasal congestion.
  • Abdominal pain: mild stomach discomfort.
  • Cough: occasional dry cough.

Serious or Rare Side Effects

  • Allergic reactions: rash, hives, swelling or anaphylaxis.
  • Mood changes: depression, suicidal thoughts or behavior.
  • Hepatotoxicity: elevated liver enzymes or hepatitis (rare).

Precautions & Warnings

When prescribing Leukast, clinicians should consider several precautionary measures.

  • Pregnancy: Category B, use only if benefit outweighs risk.
  • Liver impairment: monitor hepatic function in patients with liver disease.
  • Concomitant asthma therapy: do not discontinue inhaled corticosteroids without medical advice.
  • Age considerations: safety in children under 12 months not established.
  • Drug interactions: review patient’s medication list for potential interactions.
  • Store at ambient temperature: keep below 25 °C, retain in original packaging and protect from moisture.

Avoid Interactions

Leukast can interact with other medicines, affecting its efficacy or safety.

Major Interactions (Avoid)

  • Ritonavir: may increase montelukast plasma concentrations.
  • Phenobarbital: may reduce montelukast levels, decreasing effectiveness.

Moderate Interactions (Monitor Closely)

  • Fluconazole: may raise montelukast exposure modestly.
  • Carbamazepine: may lower montelukast concentrations.
  • Warfarin: monitor INR as montelukast may affect anticoagulation.

Frequently Asked Questions

Leukast contains montelukast, which is prescribed for persistent asthma, exercise‑induced bronchoconstriction, and allergic rhinitis. It helps control symptoms, reduce flare‑ups, and improve breathing in patients with these respiratory and allergic conditions.

Montelukast blocks the cysteinyl leukotriene receptor CysLT1, preventing leukotrienes from causing airway narrowing, mucus production, and inflammation. By inhibiting this pathway, it reduces bronchoconstriction and allergic responses in the respiratory tract.

The dosage of Leukast is determined by a qualified prescriber based on the patient’s age, weight, and specific condition. Healthcare professionals select the appropriate strength and dosing schedule according to clinical guidelines.

Leukast is classified as Pregnancy Category B, indicating no evidence of risk in animal studies but limited human data. It may be used during pregnancy only if the potential benefit justifies the risk, and breastfeeding mothers should consult their physician.

To request Leukast, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Leukast belongs to the leukotriene receptor antagonist class, offering an oral alternative to inhaled corticosteroids or long‑acting beta‑agonists. It is particularly useful for patients with aspirin‑intolerant asthma or those who need additional control beyond inhaled therapy, though it does not replace rescue bronchodilators.

Leukast tablets should be stored at ambient temperature, preferably below 25 °C. Keep them in the original container, protect from moisture and direct sunlight, and ensure they are out of reach of children.

Leukast is taken orally, usually once daily in the evening, with or without food, as directed by the prescribing clinician. Swallow the tablet whole; do not crush or chew unless specifically instructed.

Serious adverse events, though rare, include severe allergic reactions such as rash, hives, swelling, or anaphylaxis, as well as neuropsychiatric effects like depression, suicidal thoughts, or behavior. Patients should seek immediate medical attention if any of these symptoms occur.

Leukast is contraindicated in individuals with known hypersensitivity to montelukast or any component of the formulation. It should also be used with caution in patients with severe liver impairment, and it is not recommended for children under the age approved for the specific dosage form.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.