Product image of Levebon (Levetiracetam) supplied by GNH India

Levebon

Active Ingredient:
Levetiracetam
Origin:
EU

Levebon (Levetiracetam)

Levetiracetam, the active ingredient in Levebon, is an anticonvulsant presented as an oral tablet for oral use. It treats partial seizures, generalized tonic‑clonic seizures and myoclonic seizures in patients diagnosed with epilepsy, helping to reduce seizure frequency and severity.
GNH India supplies Levebon as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

G.L. Pharma Gmbh

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Indications & Clinical Uses

  • Levetiracetam is employed to manage epileptic seizure disorders across several seizure types.
  • Partial seizures: reduces the frequency of focal onset seizures and improves seizure control.
  • Generalized tonic‑clonic seizures: helps prevent convulsive episodes and lowers seizure recurrence.
  • Myoclonic seizures: decreases the occurrence of sudden muscle jerks and improves daily functioning.

How It Works

  • Levetiracetam binds selectively to the synaptic vesicle protein SV2A, modulating neurotransmitter release and stabilizing neuronal membranes. This interaction reduces abnormal neuronal firing and excitability, thereby diminishing the initiation and propagation of epileptic seizures without directly affecting ion channels or GABA receptors.

Side Effects

Levetiracetam may cause a range of adverse reactions. Monitoring and reporting are important for patient safety.

Common Side Effects

  • Dizziness
  • Somnolence
  • Fatigue
  • Headache
  • Irritability
  • Nausea

Serious or Rare Side Effects

  • Severe allergic reactions such as anaphylaxis
  • Stevens‑Johnson syndrome or toxic epidermal necrolysis
  • Suicidal thoughts or severe depression
  • Blood dyscrasias including neutropenia or thrombocytopenia
  • Hepatic failure or significant liver enzyme elevation

Precautions & Warnings

  • Before initiating therapy, clinicians should consider several precautionary measures.
  • Renal impairment: adjust dose based on renal function and monitor serum levels.
  • Hepatic impairment: evaluate liver function and consider dose modification.
  • Pregnancy: risk category unknown; discuss potential benefits and risks with the patient.
  • Breastfeeding: unknown safety; weigh maternal benefits against possible infant exposure.
  • Concomitant CNS depressants: may increase sedation and should be used with caution.
  • Store at room temperature: keep in the original packaging, protect from moisture and excessive heat.

Avoid Interactions

Levetiracetam can interact with other medicines, requiring attention to avoid reduced efficacy or increased toxicity.

Major Interactions (Avoid)

  • Carbamazepine: enzyme induction may lower levetiracetam concentrations.
  • Phenytoin: may reduce levetiracetam plasma levels.
  • Phenobarbital: can decrease levetiracetam exposure through hepatic induction.
  • Valproic acid: may increase levetiracetam levels and risk of adverse effects.

Moderate Interactions (Monitor Closely)

  • Alcohol: additive CNS depression may enhance sedation.
  • Sedative antihistamines: can increase drowsiness.
  • Other antiepileptics: may have additive seizure‑control effects requiring dose adjustments.

Frequently Asked Questions

Levebon contains levetiracetam, an antiepileptic medication prescribed to control partial seizures, generalized tonic‑clonic seizures and myoclonic seizures in patients with epilepsy. It helps reduce the frequency and severity of seizure episodes when used as part of a comprehensive treatment plan.

Levetiracetam binds to the synaptic vesicle protein SV2A, which modulates neurotransmitter release. This action stabilizes neuronal membranes and decreases abnormal neuronal excitability, thereby preventing the initiation and spread of epileptic seizures without directly influencing ion channels or GABA receptors.

The appropriate dose of Levebon is determined individually by a qualified prescriber based on the patient’s age, seizure type, renal function and overall clinical condition. Dosage regimens are tailored to achieve optimal seizure control while minimizing adverse effects.

Levetiracetam’s pregnancy category is listed as unknown, and safety data for breastfeeding are limited. Healthcare providers should evaluate the potential benefits against possible risks and discuss alternative options with patients who are pregnant or nursing.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Levebon (levetiracetam) offers a distinct mechanism by targeting SV2A, which differs from sodium‑channel blockers like carbamazepine or GABA‑enhancers such as valproic acid. It is generally well‑tolerated, has fewer drug‑enzyme interactions, and may be preferred when rapid titration or minimal hepatic metabolism is desired.

Levebon should be stored at room temperature, below 25 °C, in its original packaging to protect it from moisture and light. Keep the product out of reach of children and avoid storing in humid or excessively hot environments.

Levebon is taken orally, usually as a tablet, with or without food. The exact administration schedule—once daily or twice daily—depends on the prescriber’s instructions and the patient’s therapeutic needs.

Serious risks include severe allergic reactions such as anaphylaxis, skin disorders like Stevens‑Johnson syndrome, and neuropsychiatric events such as suicidal thoughts or severe depression. Patients should be monitored closely for any new or worsening symptoms and seek immediate medical attention if serious reactions occur.

Levebon is contraindicated in patients with known hypersensitivity to levetiracetam or any of its excipients. Caution is also advised for individuals with severe renal impairment, uncontrolled psychiatric conditions, or those taking interacting enzyme‑inducing antiepileptic drugs without appropriate monitoring.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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