Product image of Levemir Flexpen (Insulin Detemir) supplied by GNH India

Levemir Flexpen

Active Ingredient:
Insulin Detemir
Origin:
EU

Levemir Flexpen (Insulin Detemir)

Insulin detemir, the active ingredient in Levemir Flexpen, is a long‑acting insulin analog presented as a prefilled pen injection solution for subcutaneous use. It treats diabetes mellitus by providing basal insulin coverage in both type 1 and type 2 diabetes patients.

GNH India supplies Levemir Flexpen as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Novo Nordisk A/S

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Levemir Flexpen (insulin detemir) is used as basal insulin therapy in diabetes management.

  • Type 1 diabetes mellitus: provides basal insulin to maintain glycemic control.
  • Type 2 diabetes mellitus: adds basal insulin when oral agents are insufficient.
  • Pediatric diabetes (age ≥2 years): supplies basal insulin for children with type 1 diabetes.

How It Works

  • Insulin detemir binds to insulin receptors on peripheral tissues, stimulating glucose uptake and inhibiting hepatic glucose production. Its fatty‑acid side chain promotes reversible albumin binding, resulting in a prolonged and stable plasma concentration that delivers consistent basal insulin coverage over 24 hours.

Side Effects

Levemir Flexpen may cause a range of adverse reactions.

Common Side Effects

  • Hypoglycemia: low blood glucose levels, especially if meals are missed.
  • Injection site reactions: redness, swelling, or itching at the injection site.
  • Weight gain: modest increase associated with improved glycemic control.
  • Lipodystrophy: localized changes in fat tissue at injection sites.
  • Edema: mild fluid retention, particularly in the lower extremities.
  • Headache: occasional mild to moderate headache.

Serious or Rare Side Effects

  • Severe hypoglycemia: profound low glucose requiring assistance.
  • Allergic reactions: rash, urticaria, or anaphylaxis.
  • Insulin antibody formation: may alter insulin effectiveness.
  • Lipohypertrophy: significant thickening of subcutaneous tissue.
  • Unexplained weight loss: may indicate inadequate insulin dosing.

Precautions & Warnings

When using Levemir Flexpen, consider the following precautions.

  • Dose adjustment: titrate based on regular blood glucose monitoring.
  • Renal impairment: monitor closely as insulin clearance may be reduced.
  • Hepatic impairment: assess liver function and adjust dose if needed.
  • Pregnancy: use only if benefits outweigh potential risks.
  • Concomitant medications: avoid combining with other agents that increase hypoglycemia risk.
  • Store at 2‑8 °C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Levemir Flexpen can interact with several drug classes.

Major Interactions (Avoid)

  • Rapid‑acting insulin bolus without dose adjustment: may cause severe hypoglycemia.
  • Beta‑blockers: can mask hypoglycemia symptoms.

Moderate Interactions (Monitor Closely)

  • Sulfonylureas: increase risk of hypoglycemia.
  • Alcohol: potentiates hypoglycemic effect.
  • Thiazolidinediones: may exacerbate fluid retention.
  • ACE inhibitors: may enhance insulin sensitivity.
  • Corticosteroids: can raise blood glucose, requiring dose changes.

Frequently Asked Questions

Levemir Flexpen contains insulin detemir, a long‑acting insulin analog used as basal insulin therapy to help control blood glucose levels in adults and children with type 1 or type 2 diabetes.

Insulin detemir binds to insulin receptors, promoting glucose uptake in muscle and fat and suppressing hepatic glucose production. Its fatty‑acid side chain enables reversible albumin binding, providing a prolonged, steady insulin level for up to 24 hours.

The dose of Levemir Flexpen is individualized. A qualified prescriber determines the appropriate amount based on the patient’s blood‑glucose profile, body weight, diet, activity level, and other medications.

Safety in pregnancy and lactation has not been fully established. It should be used only if the potential benefit justifies any possible risk to the fetus or infant, and under close medical supervision.

To order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed) and import documentation.

Levemir Flexpen (insulin detemir) offers a once‑daily or twice‑daily dosing schedule with a relatively flat pharmacokinetic profile. Compared with other basal insulins such as glargine, detemir may have a slightly shorter duration of action, which can be advantageous for patients needing flexible dosing intervals.

Store the pen at 2‑8 °C (refrigerated) and protect it from light. Do not freeze or shake the pen. Once in use, it may be kept at room temperature (up to 30 °C) for up to 28 days, as indicated in the product labeling.

Levemir Flexpen is a prefilled pen for subcutaneous injection. The pen is primed according to the instructions, the dose is set on the dial, and the injection is given into the abdomen, thigh, or upper arm, rotating sites to reduce lipodystrophy.

The most serious risks include severe hypoglycemia, which can cause loss of consciousness or seizures, and allergic reactions ranging from rash to anaphylaxis. Patients should be educated on recognizing early signs of low blood glucose and on proper injection technique.

Levemir Flexpen should not be used by individuals with a known hypersensitivity to insulin detemir or any of the pen’s excipients. Caution is advised in patients with severe renal or hepatic impairment, and it is contraindicated in those with recurrent severe hypoglycemia without appropriate monitoring.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Related Products

Other formulations containing Insulin Detemir

A

A
A

A
A

A
A

A

Browse all products →

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Regulatory recognitions

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.

SGS GSDP Certification

GSDP Compliant from SGS

URS ISO 9001

URS ISO 9001 Certification

FDA Maharashtra

Licensed by FDA Maharashtra

IEC License DGFT

IEC License issued by DGFT