Product image of Levemir Penfill (Insulin Detemir) supplied by GNH India

Levemir Penfill

Active Ingredient:
Insulin Detemir
Origin:
EU

Levemir Penfill (Insulin Detemir)

Insulin detemir, the active ingredient in Levemir Penfill, is an insulin analog presented as a pre‑filled pen solution for subcutaneous injection. It delivers long‑acting basal insulin to help regulate blood glucose in adults and children with type 1 or type 2 diabetes mellitus. Its prolonged duration of action reduces the need for multiple daily injections and provides a stable insulin level throughout the day.

GNH India supplies Levemir Penfill as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides cold‑chain logistics to ensure product integrity during global distribution.

Manufacturer / TM Owner

Novo Nordisk A/S

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Levemir Penfill (insulin detemir) provides basal insulin therapy for diabetes mellitus.

  • Type 1 diabetes mellitus: maintains basal glucose control and reduces hyperglycaemic episodes.
  • Type 2 diabetes mellitus: complements oral agents or other insulin regimens to achieve fasting glucose targets.

How It Works

  • Insulin detemir binds to insulin receptors on peripheral tissues, stimulating glucose uptake into muscle and adipose cells while suppressing hepatic glucose production. Its fatty‑acid side chain promotes reversible albumin binding, prolonging its circulation time and delivering a steady basal insulin effect over 24 hours.

Side Effects

Levemir Penfill may cause adverse reactions that vary in frequency and severity.

Common Side Effects

  • Hypoglycaemia: low blood‑sugar episodes, especially if meals are missed or dose is excessive.
  • Injection site reactions: redness, swelling or itching at the injection site.
  • Weight gain: modest increase due to improved glucose utilisation.
  • Lipodystrophy: localized changes in fat tissue with repeated injections.
  • Edema: mild fluid retention, particularly in the lower extremities.
  • Headache: occasional mild headache.

Serious or Rare Side Effects

  • Severe hypoglycaemia: profound low blood glucose requiring assistance.
  • Anaphylactic reaction: rare systemic allergic response with rash, breathing difficulty.
  • Allergic dermatitis: severe skin reaction at injection sites.
  • Hypokalemia: low potassium levels in rare cases.
  • Acute insulin allergy: immediate hypersensitivity requiring medical attention.
  • Serum insulin antibodies: formation of antibodies that may alter insulin action.

Precautions & Warnings

Before using Levemir Penfill, consider the following safety measures.

  • Blood‑glucose monitoring: check glucose levels regularly to adjust dose as needed.
  • Renal or hepatic impairment: dose may require adjustment; monitor closely.
  • Hypersensitivity: discontinue if signs of allergic reaction appear.
  • Pregnancy and lactation: use only if benefits outweigh risks; consult prescriber.
  • Patient education: ensure understanding of hypoglycaemia signs and management.
  • Store at 2‑8 °C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Levemir Penfill can interact with other medicines, affecting glucose control.

Major Interactions (Avoid)

  • Concomitant use of other rapid‑acting insulins: may cause severe hypoglycaemia.
  • Beta‑blockers: can mask hypoglycaemia symptoms, complicating detection.

Moderate Interactions (Monitor Closely)

  • Sulfonylureas or meglitinides: increase risk of hypoglycaemia; dose adjustments may be needed.
  • Corticosteroids: may raise glucose requirements, necessitating higher insulin doses.
  • Thiazide diuretics: can impair glucose tolerance, requiring closer monitoring.
  • ACE inhibitors: may potentiate insulin’s glucose‑lowering effect in some patients.

Frequently Asked Questions

Levemir Penfill contains insulin detemir, a long‑acting basal insulin used to control blood glucose in adults and children with type 1 or type 2 diabetes mellitus. It provides a steady insulin level throughout the day, helping to prevent fasting hyperglycaemia and reduce the need for multiple daily injections.

Insulin detemir binds to insulin receptors on muscle, fat and liver cells, promoting glucose uptake and inhibiting hepatic glucose production. Its fatty‑acid side chain enables reversible binding to albumin, extending its circulation time and delivering a consistent basal insulin effect for up to 24 hours.

The dose of Levemir Penfill is individualized and set by a qualified prescriber based on the patient’s age, weight, renal function, dietary habits and current glycaemic control. Patients should follow the dosing instructions provided by their healthcare professional and adjust only under medical supervision.

Insulin detemir is classified as Pregnancy Category B, indicating that animal studies have not shown risk to the fetus and there are no adequate human studies. It may be used during pregnancy or lactation when the prescriber determines that the benefit outweighs any potential risk.

To place an order, submit an enquiry on the Levemir Penfill product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, cold‑chain shipping details and any necessary import documentation.

Levemir Penfill (insulin detemir) offers a prolonged, relatively flat basal profile similar to insulin glargine, but its albumin‑binding mechanism may result in slightly less variability between doses. Both are once‑daily options; choice often depends on patient preference, cost, and individual response as assessed by the treating clinician.

Levemir Penfill should be stored in a refrigerator at 2‑8 °C. Keep the pen in its original carton, protect it from light, and avoid freezing. Once in use, the pen may be kept at controlled room temperature (up to 30 °C) for a maximum of 28 days, after which it should be discarded.

Levemir Penfill is administered subcutaneously using the pre‑filled pen. The injection site can be the abdomen, thigh, upper arm or buttock, rotating sites with each dose. Patients should follow the pen’s instructions for dose selection, needle attachment and disposal, and always inject at a 90° angle.

The most serious risks include severe hypoglycaemia, which can cause loss of consciousness or seizures, and rare allergic reactions such as anaphylaxis. Patients should be educated on recognising early hypoglycaemia signs, carrying glucose sources, and seeking immediate medical attention if a severe reaction occurs.

Levemir Penfill is contraindicated in individuals with a known hypersensitivity to insulin detemir or any of the pen’s excipients. It should also be avoided in patients with severe hypoglycaemia unawareness unless closely supervised, and in those for whom basal insulin therapy is not indicated by their treating physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.