Product image of Levesialle Diario (Ethinylestradiol, Levonorgestrel | Lactose) supplied by GNH India

Levesialle Diario

Active Ingredient:
Ethinylestradiol, Levonorgestrel | Lactose
Origin:
EU

Levesialle Diario (Ethinylestradiol, Levonorgestrel | Lactose)

Ethinylestradiol and Levonorgestrel, the active ingredients in Levesialle Diario, are a combined oral contraceptive presented as a tablet for oral use. They prevent pregnancy in women of reproductive age.

GNH India supplies Levesialle Diario as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Exeltis Healthcare S.L

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Indications & Clinical Uses

Levesialle Diario, a combined oral contraceptive, is used within the hormonal birth‑control family to prevent unintended pregnancy.

  • Contraception: prevents pregnancy by inhibiting ovulation and altering cervical mucus.
  • Family planning: provides a reliable hormonal method for women seeking birth control.
  • Pregnancy prevention: reduces the risk of unintended pregnancy when taken as prescribed.

How It Works

  • Ethinylestradiol and levonorgestrel act on the hypothalamic‑pituitary‑ovarian axis. Ethinylestradiol provides estrogenic feedback that suppresses the mid‑cycle surge of luteinizing hormone (LH) and follicle‑stimulating hormone (FSH), while levonorgestrel, a progestogen, reinforces this suppression, prevents follicular development, thickens cervical mucus, and induces endometrial changes that are unfavorable for implantation.

Side Effects

Levesialle Diario may cause a range of adverse reactions.

Common Side Effects

  • Nausea: mild to moderate stomach upset.
  • Headache: tension‑type or migraine‑like pain.
  • Breast tenderness: swelling or discomfort.
  • Spotting: irregular vaginal bleeding.

Serious or Rare Side Effects

  • Deep vein thrombosis: blood clot formation in deep veins.
  • Pulmonary embolism: clot migration to lung vessels.
  • Stroke: cerebrovascular accident due to clot or hemorrhage.
  • Severe allergic reaction: rash, swelling, or anaphylaxis.

Precautions & Warnings

Before using Levesialle Diario, consider the following precautions.

  • Smoking: avoid if you smoke more than 15 cigarettes per day, as risk of cardiovascular events increases.
  • Pregnancy: contraindicated; do not start if you are pregnant or suspect pregnancy.
  • History of thromboembolism: consult a healthcare professional if you have past blood‑clot events.
  • Liver disease: use with caution in patients with active liver disease.
  • Store at room temperature below 25°C: keep in the original pack, protect from moisture and direct sunlight.

Avoid Interactions

Levesialle Diario can interact with other medicines.

Major Interactions (Avoid)

  • Rifampin (antibiotic): may reduce contraceptive effectiveness.
  • Carbamazepine (antiepileptic): may lower hormone levels and increase failure risk.
  • Efavirenz (antiretroviral): can diminish contraceptive efficacy.

Moderate Interactions (Monitor Closely)

  • Ketoconazole (antifungal): may increase hormone concentrations, raising side‑effect risk.
  • St. John’s wort (herbal supplement): may decrease contraceptive effectiveness.
  • Diuretics: may affect blood pressure control while on hormonal therapy.

Frequently Asked Questions

Levesialle Diario is a combined oral contraceptive containing ethinylestradiol and levonorgestrel. It is prescribed to prevent pregnancy in women of reproductive age by suppressing ovulation and altering cervical mucus, providing a reliable hormonal method for family planning.

Ethinylestradiol supplies estrogenic feedback that suppresses the mid‑cycle surge of luteinizing hormone (LH) and follicle‑stimulating hormone (FSH). Levonorgestrel, a progestogen, reinforces this suppression, prevents follicular development, thickens cervical mucus, and induces endometrial changes that are unfavorable for implantation.

The specific dosing regimen is determined by the prescribing healthcare professional. Typically, the medication is taken as one tablet daily at the same time each day, but the exact schedule and duration are set by the prescriber based on individual needs.

Levesialle Diario is contraindicated during pregnancy and should not be started by a woman who is pregnant or suspects pregnancy. While limited data exist for breastfeeding, the product is generally not recommended unless the benefits outweigh potential risks; a healthcare provider should be consulted.

To order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, and will request verification of trade or institutional credentials before providing pricing, availability, shipping details and any necessary import documentation.

Levesialle Diario contains the classic ethinylestradiol‑levonorgestrel combination, which is widely used and well‑studied. Compared with newer formulations that include drospirenone or desogestrel, it offers similar contraceptive efficacy but may have a different side‑effect profile, such as a slightly higher risk of weight gain and less impact on acne.

Store the tablets at room temperature below 25 °C, in the original blister pack or container. Protect them from moisture, excessive heat and direct sunlight. Do not use tablets that are discolored, broken or past the expiration date.

Levesialle Diario is taken orally as a tablet, usually with a glass of water. It should be taken at the same time each day, without crushing or chewing, to maintain consistent hormone levels and effectiveness.

Serious risks include venous thromboembolism such as deep‑vein thrombosis or pulmonary embolism, arterial events like stroke or myocardial infarction, and severe allergic reactions. Women with a history of clotting disorders, smoking heavily, or with certain cardiovascular conditions should be closely monitored or avoid use.

Levesialle Diario is contraindicated for women who are pregnant, breastfeeding (unless advised by a physician), have a history of thromboembolic disease, uncontrolled hypertension, active liver disease, known or suspected hormone‑dependent tumors, or who smoke more than 15 cigarettes per day.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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