Product image of Levest (Ethinylestradiol, Levonorgestrel) supplied by GNH India

Levest

Active Ingredient:
Ethinylestradiol, Levonorgestrel
Origin:
EU

Levest (Ethinylestradiol, Levonorgestrel)

Ethinylestradiol, the active ingredient in Levest, is a combined oral contraceptive presented as an oral tablet for oral use. It works together with levonorgestrel, a synthetic progestogen, to provide reliable hormonal contraception for women of reproductive age. The formulation combines ethinylestradiol, a synthetic estrogen, with levonorgestrel to prevent ovulation and create unfavorable conditions for fertilisation.

GNH India supplies Levest as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Morningside Healthcare Ltd

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Indications & Clinical Uses

Levest, a combined oral contraceptive, is indicated for hormonal contraception.

  • Contraception: prevents pregnancy in women of reproductive potential.
  • Menstrual cycle regulation: helps achieve more predictable menstrual bleeding patterns.

How It Works

  • Levest contains ethinylestradiol, a synthetic estrogen, and levonorgestrel, a synthetic progestogen. The estrogen component suppresses follicular development, while the progestogen inhibits the luteinising hormone surge, preventing ovulation. Both agents also thicken cervical mucus and alter the endometrial lining, reducing the likelihood of fertilisation and implantation.

Side Effects

Levest may cause a range of adverse reactions.

Common Side Effects

  • Nausea: mild stomach upset.
  • Headache: tension‑type discomfort.
  • Breast tenderness: mild discomfort or swelling.
  • Spotting: irregular vaginal bleeding.

Serious or Rare Side Effects

  • Deep vein thrombosis: formation of blood clots in leg veins.
  • Pulmonary embolism: clot migration to the lungs, potentially life‑threatening.
  • Severe allergic reaction: rash, swelling, or difficulty breathing requiring immediate medical attention.

Precautions & Warnings

Before prescribing Levest, consider the following precautions:

  • Assess thrombotic risk: avoid use in women with a history of clotting disorders.
  • Screen for hypertension: monitor blood pressure regularly during therapy.
  • Avoid smoking: especially in women older than 35 years.
  • Consider liver function: contraindicated in severe hepatic disease.
  • Store at ambient temperature: keep below 25°C, protect from moisture and light.

Avoid Interactions

Levest can interact with several medicines, altering its effectiveness or safety.

Major Interactions (Avoid)

  • Antiepileptic enzyme inducers (e.g., carbamazepine, phenytoin): reduce contraceptive efficacy.
  • Rifampin: decreases hormone levels, increasing risk of unintended pregnancy.
  • St. John’s wort: may lower effectiveness of hormonal contraception.

Moderate Interactions (Monitor Closely)

  • Antifungal azoles (e.g., ketoconazole): may increase hormone concentrations, requiring monitoring for side effects.
  • Certain antibiotics (e.g., tetracycline): may slightly reduce effectiveness; advise backup contraception.

Frequently Asked Questions

Levest is a combined oral contraceptive tablet that contains ethinylestradiol and levonorgestrel. It is prescribed to prevent pregnancy in women of reproductive age by inhibiting ovulation and creating conditions that are unfavorable for fertilisation and implantation.

Ethinylestradiol is a synthetic estrogen that suppresses the growth of ovarian follicles and stabilises the endometrial lining. In combination with levonorgestrel, it helps prevent the surge of luteinising hormone, thereby blocking ovulation and contributing to contraceptive efficacy.

The specific dosing regimen for Levest is determined by the prescribing healthcare professional. Typically, the medication is taken once daily at the same time each day, but the exact schedule and any missed‑dose instructions are provided by the prescriber.

Levest is classified as Pregnancy Category X, meaning it is contraindicated during pregnancy because it can cause fetal harm. Use while breastfeeding should be discussed with a healthcare provider, as hormonal contraceptives may affect milk production and infant exposure.

To order Levest, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Levest contains the standard dose combination of ethinylestradiol and levonorgestrel, which is comparable to many other combined oral contraceptives on the market. Its efficacy, safety profile, and side‑effect spectrum are similar to other products that use the same hormonal components, though individual tolerability may vary.

Levest tablets should be stored at ambient temperature, below 25 °C, in their original packaging. Protect them from excess moisture, heat, and direct sunlight. Keep the container tightly closed and out of reach of children.

Levest is taken orally as a tablet. The usual practice is to swallow one tablet each day, preferably at the same time each day, with or without food, as directed by the prescribing clinician.

The most serious risks include venous thromboembolism such as deep‑vein thrombosis, pulmonary embolism, and rare arterial events like stroke or myocardial infarction. Severe allergic reactions and liver disorders are also rare but potentially life‑threatening complications that require immediate medical attention.

Levest is contraindicated in women who are pregnant, have a history of thromboembolic disorders, uncontrolled hypertension, severe liver disease, known or suspected breast cancer, or who are smokers over the age of 35. It should also be avoided in individuals with known hypersensitivity to any component of the tablet.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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