Product image of Levetiracetam 1 A Pharma (Levetiracetam) supplied by GNH India

Levetiracetam 1 A Pharma

Active Ingredient:
Levetiracetam
Origin:
EU

Levetiracetam 1 A Pharma (Levetiracetam)

Levetiracetam, the active ingredient in Levetiracetam 1 A Pharma, is an anticonvulsant presented as an oral tablet for oral use. It is employed to manage various seizure types in patients diagnosed with epilepsy.

GNH India supplies Levetiracetam 1 A Pharma as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

1 A Pharma Gmbh

1
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Indications & Clinical Uses

Levetiracetam is an antiepileptic medication used to control seizure activity across several seizure disorders.

  • Partial seizures: reduces the frequency and severity of focal onset seizures.
  • Generalized tonic‑clonic seizures: helps prevent convulsive episodes that involve the whole brain.
  • Myoclonic seizures: diminishes sudden, brief muscle jerks characteristic of this seizure type.

How It Works

  • Levetiracetam binds to the synaptic vesicle protein SV2A, modulating neurotransmitter release and stabilising neuronal membranes. This interaction reduces abnormal neuronal firing and overall excitability, contributing to seizure control without directly affecting ion channels or GABA receptors.

Side Effects

Levetiracetam may cause a range of adverse reactions, most of which are mild to moderate in intensity.

Common Side Effects

  • Dizziness: sensation of light‑headedness or unsteadiness.
  • Fatigue: persistent tiredness not relieved by rest.
  • Headache: mild to moderate cranial pain.
  • Irritability: increased emotional sensitivity.
  • Nasopharyngitis: upper respiratory tract infection symptoms.
  • Nausea: feeling of stomach upset.

Serious or Rare Side Effects

  • Severe allergic reaction: rash, swelling, or breathing difficulty.
  • Mood changes: depression or suicidal thoughts.
  • Aggression or hostility: marked behavioral alterations.
  • Blood disorders: signs of anemia or low platelet count.
  • Hepatic dysfunction: jaundice or abnormal liver enzymes.
  • Stevens‑Johnson syndrome: severe skin blistering.

Precautions & Warnings

Before initiating therapy, clinicians should evaluate patient history and monitor for specific concerns.

  • Renal impairment: adjust dose based on creatinine clearance.
  • Hepatic disease: use with caution, monitor liver function.
  • Psychiatric history: observe for mood or behavioral changes.
  • Concomitant CNS depressants: assess additive sedation risk.
  • Pregnancy and lactation: discuss unknown safety profile with the patient.
  • Store at ambient temperature: keep below 25 °C, retain original packaging, protect from moisture.

Avoid Interactions

Levetiracetam can interact with other medicines, influencing efficacy or safety.

Major Interactions (Avoid)

  • Carbamazepine: may reduce levetiracetam plasma levels.
  • Phenobarbital: can lower levetiracetam exposure.

Moderate Interactions (Monitor Closely)

  • Fluoroquinolone antibiotics: increased risk of CNS side effects.
  • Opioids: potential for enhanced sedation.
  • Alcohol: may exacerbate dizziness and drowsiness.
  • Other antiepileptics: monitor overall seizure control and side‑effect burden.

Frequently Asked Questions

Levetiracetam 1 A Pharma is prescribed to treat partial (focal) seizures, generalized tonic‑clonic seizures, and myoclonic seizures in patients with epilepsy. It helps reduce the frequency and intensity of seizure episodes across these recognized seizure types.

Levetiracetam binds to the synaptic vesicle protein SV2A, which modulates neurotransmitter release. By stabilising neuronal firing and decreasing abnormal excitability, it lowers the likelihood of seizure generation without directly influencing ion channels or GABA receptors.

The dosage of Levetiracetam 1 A Pharma is individualized by the prescribing clinician based on the patient’s age, renal function, seizure type, and therapeutic response. The prescriber determines the appropriate dose and titration schedule.

The safety of levetiracetam in pregnancy and lactation has not been definitively established. Healthcare providers should weigh potential benefits against unknown risks and discuss alternative options with patients who are pregnant or nursing.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Levetiracetam offers a distinct mechanism by targeting SV2A, which can result in fewer drug‑drug interactions compared with enzyme‑inducing antiepileptics such as carbamazepine or phenytoin. It is generally well‑tolerated, but clinicians consider individual seizure patterns, comorbidities and side‑effect profiles when selecting therapy.

Store the tablets at ambient temperature, preferably below 25 °C. Keep them in the original packaging to protect from moisture and light, and ensure the container is tightly closed throughout its shelf life.

Levetiracetam 1 A Pharma is taken orally, usually with or without food, as directed by the prescriber. Tablets should be swallowed whole with water and not chewed or crushed unless specifically instructed.

Serious risks include severe allergic reactions (e.g., Stevens‑Johnson syndrome), mood alterations such as depression or suicidal thoughts, and rare blood disorders. Patients should seek immediate medical attention if they experience rash, mood changes, or signs of infection.

Patients with known hypersensitivity to levetiracetam or any of its excipients should avoid the medication. Caution is also advised for individuals with severe renal impairment, uncontrolled psychiatric conditions, or those taking interacting CNS depressants without close monitoring.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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