Product image of Levetiracetam 1a Farma (Levetiracetam) supplied by GNH India

Levetiracetam 1a Farma

Active Ingredient:
Levetiracetam
Origin:
EU

Levetiracetam 1a Farma (Levetiracetam)

Levetiracetam, the active ingredient in Levetiracetam 1a Farma, is an anticonvulsant presented as an oral tablet for oral use. It is prescribed to manage various seizure types in patients diagnosed with epilepsy, including partial and generalized tonic‑clonic seizures. It helps reduce neuronal excitability by targeting synaptic vesicle protein SV2A.

GNH India supplies Levetiracetam 1a Farma as a licensed, GDP‑compliant international pharmaceutical supplier, adhering to EU quality standards and providing the product to hospitals, pharmacies and clinics worldwide through regulated distribution channels.

Manufacturer / TM Owner

1a Farma A/S

1
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Indications & Clinical Uses

Levetiracetam is an antiepileptic medication used to control seizure activity in various forms of epilepsy.

  • Partial seizures: decreases the frequency of focal onset seizures, with or without secondary generalization.
  • Generalized tonic‑clonic seizures: helps prevent the occurrence of primary generalized convulsive seizures.
  • Epilepsy (overall seizure control): contributes to overall reduction in seizure burden as part of a comprehensive treatment plan.

How It Works

  • Levetiracetam binds to the synaptic vesicle protein SV2A, modulating its function and thereby reducing the release of excitatory neurotransmitters. This action stabilizes neuronal membranes and diminishes hyper‑excitability, which helps prevent the initiation and spread of seizure activity in the brain.

Side Effects

Levetiracetam may cause a range of adverse reactions, most of which are mild and reversible.

Common Side Effects

  • Dizziness: transient sensation of light‑headedness.
  • Somnolence: increased sleepiness or fatigue.
  • Headache: mild to moderate cranial pain.
  • Irritability: mood changes including agitation.
  • Nausea: occasional upset stomach.
  • Fatigue: general lack of energy.

Serious or Rare Side Effects

  • Severe allergic reactions: rash, swelling, or anaphylaxis.
  • Stevens‑Johnson syndrome: rare but serious skin disorder.
  • Suicidal thoughts or behavior: new or worsening depression.
  • Severe skin rash: extensive erythema or blistering.
  • Blood dyscrasias: neutropenia or thrombocytopenia.
  • Hepatic dysfunction: elevated liver enzymes or hepatitis.

Precautions & Warnings

When prescribing levetiracetam, clinicians should consider several safety aspects.

  • Dose adjustment in renal impairment: modify dose based on creatinine clearance.
  • Monitor for mood changes: watch for depression or suicidal ideation.
  • Avoid abrupt discontinuation: taper under medical supervision to prevent seizure worsening.
  • Use caution in pregnancy: limited data, assess risk versus benefit.
  • Store at ambient temperature: keep below 25°C, protect from moisture and light in the original container.

Avoid Interactions

Levetiracetam can interact with other medicines, affecting its efficacy or safety.

Major Interactions (Avoid)

  • Concomitant use with carbamazepine: may reduce levetiracetam plasma levels.
  • Co‑administration with enzyme‑inducing antiepileptics (phenytoin, phenobarbital): may decrease efficacy.
  • Strong inhibitors of renal tubular secretion (e.g., probenecid): may increase levetiracetam concentrations.

Moderate Interactions (Monitor Closely)

  • Combination with other CNS depressants (benzodiazepines, alcohol): may enhance sedation.
  • Use with antidepressants (SSRIs): monitor for behavioral changes.

Frequently Asked Questions

Levetiracetam 1a Farma is an oral antiepileptic drug indicated for the treatment of partial seizures, generalized tonic‑clonic seizures, and for overall seizure control in patients with epilepsy. It helps reduce the frequency and severity of seizure episodes when used as part of a comprehensive management plan.

Levetiracetam binds to the synaptic vesicle protein SV2A, a key regulator of neurotransmitter release. By modulating SV2A, the drug decreases the release of excitatory neurotransmitters, stabilizing neuronal activity and lowering the likelihood of seizure initiation and propagation.

The dosage of Levetiracetam 1a Farma is individualized. A qualified prescriber determines the appropriate dose based on the patient’s age, weight, renal function, seizure type, and response to therapy. Patients should follow the prescribing clinician’s instructions and not adjust the dose on their own.

Safety data for levetiracetam in pregnancy and lactation are limited, and the pregnancy category is listed as unknown. Clinicians weigh potential benefits against possible risks, and the drug should only be used if clearly needed. Breastfeeding mothers should consult their healthcare provider for personalized advice.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Levetiracetam offers a distinct mechanism by targeting SV2A, which differs from sodium‑channel blockers like carbamazepine or GABA‑enhancers such as valproate. It is generally well tolerated, has few drug‑enzyme interactions, and does not require routine therapeutic drug monitoring, making it a convenient option for many patients.

Levetiracetam 1a Farma should be stored at ambient temperature, preferably below 25 °C. Keep the tablets in the original packaging, protect them from moisture and direct light, and ensure the container is tightly closed to maintain product stability.

Levetiracetam 1a Farma is taken orally, usually with or without food. The tablets are swallowed whole with a glass of water. Dosing frequency and timing are determined by the prescribing physician based on the individual treatment plan.

Serious risks include severe allergic reactions, Stevens‑Johnson syndrome, suicidal thoughts or behaviors, significant skin rashes, blood dyscrasias, and hepatic dysfunction. Patients should seek immediate medical attention if they experience any of these symptoms while on therapy.

Levetiracetam is contraindicated in patients with known hypersensitivity to levetiracetam or any of its excipients. Caution is advised for individuals with severe renal impairment, uncontrolled psychiatric disorders, or those who are pregnant or breastfeeding without a clear medical justification.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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