Product image of Levetiracetam 1a Farma (Levetiracetam) supplied by GNH India

Levetiracetam 1a Farma

Active Ingredient:
Levetiracetam
Origin:
EU

Levetiracetam 1a Farma (Levetiracetam)

Levetiracetam, the active ingredient in Levetiracetam 1a Farma, is an anticonvulsant presented as a tablet for oral use. It treats partial‑onset seizures, generalized tonic‑clonic seizures and myoclonic seizures in patients with epilepsy.

GNH India supplies Levetiracetam 1a Farma as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

1a Farma A/S

1
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Indications & Clinical Uses

  • Levetiracetam is used to manage several types of epileptic seizures by stabilising neuronal activity.
  • Partial‑onset seizures: reduces seizure frequency in focal epilepsy.
  • Generalized tonic‑clonic seizures: helps prevent convulsive episodes.
  • Myoclonic seizures: diminishes rapid muscle jerks associated with epilepsy.

How It Works

  • Levetiracetam binds to the synaptic vesicle protein SV2A, modulating neurotransmitter release and decreasing neuronal hyper‑excitability. This action stabilises synaptic transmission and reduces the likelihood of seizure propagation without directly affecting ion channels or GABA receptors.

Side Effects

Levetiracetam may cause a range of adverse reactions, from mild to severe.

Common Side Effects

  • Dizziness: transient feeling of light‑headedness.
  • Fatigue: general tiredness or lack of energy.
  • Headache: mild to moderate cranial pain.
  • Irritability: mood changes or increased agitation.
  • Nausea: occasional stomach upset.
  • Nasal congestion: mild blockage of nasal passages.

Serious or Rare Side Effects

  • Severe allergic reaction: rash, swelling, or difficulty breathing.
  • Mood disorders: depression or suicidal thoughts.
  • Hematologic changes: low blood cell counts.
  • Hepatic dysfunction: abnormal liver enzyme levels.
  • Severe skin reactions: Stevens‑Johnson syndrome.
  • Multifocal seizures: paradoxical increase in seizure activity.

Precautions & Warnings

  • Before initiating therapy, consider the following safety measures.
  • Pregnancy: discuss potential risks with a healthcare professional.
  • Renal impairment: dose may need adjustment based on kidney function.
  • Psychiatric history: monitor for mood changes or depression.
  • Concomitant CNS depressants: use caution as additive sedation may occur.
  • Alcohol use: avoid excessive intake as it may increase side effects.
  • Store at ambient temperature: keep below 25°C in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Levetiracetam can interact with other medicines, influencing efficacy or safety.

Major Interactions (Avoid)

  • Carbamazepine: may reduce levetiracetam plasma levels.
  • Phenobarbital: can decrease levetiracetam exposure.
  • Phenytoin: may lower levetiracetam concentrations.

Moderate Interactions (Monitor Closely)

  • Fluconazole: potential increase in levetiracetam levels.
  • Rifampicin: may modestly reduce levetiracetam exposure.
  • Valproic acid: monitor for additive CNS effects.

Frequently Asked Questions

Levetiracetam 1a Farma is prescribed to treat several seizure types in epilepsy, including partial‑onset (focal) seizures, generalized tonic‑clonic seizures, and myoclonic seizures. It helps reduce the frequency and severity of these episodes by stabilising neuronal activity.

Levetiracetam binds to the synaptic vesicle protein SV2A, which plays a key role in neurotransmitter release. By modulating SV2A, the drug decreases excessive neuronal firing and reduces the likelihood of seizure propagation without directly influencing ion channels or GABA receptors.

The specific dosage of Levetiracetam 1a Farma is determined by the prescribing clinician based on the patient’s age, weight, renal function, and seizure type. Dosage adjustments are individualized, and patients should follow the prescriber’s instructions precisely.

Safety data for levetiracetam in pregnancy and lactation are limited. Healthcare providers should evaluate the potential benefits against possible risks before prescribing to pregnant or nursing women. Women should discuss any concerns with their physician.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and necessary import documentation.

Levetiracetam offers a distinct mechanism by targeting SV2A, which differs from many antiepileptics that act on ion channels or GABA pathways. It generally has fewer drug‑enzyme interactions, a favorable tolerability profile, and does not require routine blood level monitoring, making it a convenient option for many patients.

Levetiracetam 1a Farma tablets should be stored at ambient temperature, preferably below 25 °C. Keep the medication in its original packaging, protect it from moisture, and store away from direct sunlight to maintain potency.

Levetiracetam 1a Farma is taken orally, usually with or without food, as directed by the prescriber. Tablets should be swallowed whole with water and not crushed or chewed unless specifically advised by a healthcare professional.

Serious adverse events, though rare, can include severe allergic reactions (rash, swelling, breathing difficulty), mood disturbances such as depression or suicidal thoughts, and hematologic abnormalities like low blood cell counts. Patients should seek immediate medical attention if any of these occur.

Levetiracetam is contraindicated in individuals with known hypersensitivity to levetiracetam or any of its excipients. Patients with uncontrolled severe psychiatric disorders should use it with caution, and those with significant renal impairment may require dose adjustments under medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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