Product image of Levetiracetam 1a Pharma (Levetiracetam) supplied by GNH India

Levetiracetam 1a Pharma

Active Ingredient:
Levetiracetam
Origin:
EU

Levetiracetam 1a Pharma (Levetiracetam)

Levetiracetam, the active ingredient in Levetiracetam 1a Pharma, is an anticonvulsant presented as an oral tablet for oral use. It is used to treat partial, generalized tonic‑clonic and myoclonic seizures in patients with epilepsy.

GNH India supplies Levetiracetam 1a Pharma as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

1 A Pharma Gmbh

1
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Indications & Clinical Uses

  • Levetiracetam is an antiepileptic drug indicated for several seizure types.
  • Partial seizures: reduces frequency and severity of focal onset seizures.
  • Generalized tonic‑clonic seizures: helps control convulsive episodes.
  • Myoclonic seizures: decreases occurrence of sudden muscle jerks.

How It Works

  • Levetiracetam binds to the synaptic vesicle protein SV2A, modulating neurotransmitter release and stabilizing neuronal membranes. This action reduces abnormal neuronal firing and excitability, contributing to seizure control without directly affecting ion channels or GABA receptors.

Side Effects

Levetiracetam may cause a range of adverse reactions.

Common Side Effects

  • Dizziness
  • Somnolence
  • Fatigue
  • Headache
  • Irritability
  • Nausea

Serious or Rare Side Effects

  • Severe skin reactions (e.g., Stevens‑Johnson syndrome)
  • Depression or suicidal thoughts
  • Blood dyscrasias (e.g., neutropenia)
  • Multi‑organ hypersensitivity syndrome
  • Severe allergic reactions (anaphylaxis)

Precautions & Warnings

  • When prescribing levetiracetam, consider the following precautions.
  • Monitor renal function: dose adjustment may be required in renal impairment.
  • Avoid abrupt discontinuation: taper gradually to reduce seizure recurrence.
  • Assess psychiatric history: monitor for mood changes or depression.
  • Use caution in pregnancy: limited data, weigh benefits against potential risks.
  • Store at room temperature: keep in the original container, protect from moisture.

Avoid Interactions

Levetiracetam can interact with several medications.

Major Interactions (Avoid)

  • Carbamazepine: may lower levetiracetam plasma levels.
  • Phenytoin: can reduce levetiracetam exposure.
  • Phenobarbital: may decrease levetiracetam concentrations.
  • Rifampicin: induces metabolism, lowering drug levels.
  • St. John’s wort: may reduce efficacy.

Moderate Interactions (Monitor Closely)

  • CNS depressants (e.g., benzodiazepines): may enhance sedation.
  • Hormonal contraceptives: levetiracetam may reduce contraceptive effectiveness.
  • Other antiepileptics: monitor for additive side effects.

Frequently Asked Questions

Levetiracetam 1a Pharma is an antiepileptic medication used to control partial, generalized tonic‑clonic and myoclonic seizures in patients diagnosed with epilepsy. It helps reduce the frequency and severity of seizure episodes when taken as prescribed by a healthcare professional.

Levetiracetam binds to the synaptic vesicle protein SV2A in the brain, which modulates neurotransmitter release. By stabilizing neuronal firing and decreasing abnormal excitability, it helps prevent the rapid, uncontrolled electrical activity that leads to seizures.

The appropriate dose of Levetiracetam 1a Pharma is determined by the prescribing clinician based on the patient’s age, weight, renal function and seizure type. Dosage adjustments are individualized, and patients should follow the specific instructions provided by their healthcare provider.

Safety data for levetiracetam in pregnancy and lactation are limited. The medication should only be used if the potential benefit to the mother outweighs any possible risk to the fetus or infant. Women who are pregnant, planning pregnancy, or breastfeeding should discuss risks and alternatives with their doctor.

To order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Levetiracetam differs from many traditional antiepileptics because it has a unique mechanism targeting SV2A and does not significantly affect hepatic enzymes. This results in fewer drug‑drug interactions compared with agents like carbamazepine or phenytoin, though dose adjustments may still be needed in renal impairment.

Levetiracetam 1a Pharma should be stored at room temperature, below 25 °C, in its original packaging. Keep the product away from moisture and direct sunlight to maintain stability and potency throughout its shelf life.

Levetiracetam is taken orally, usually as a tablet. It can be swallowed whole with water, and may be taken with or without food. The exact dosing schedule—once, twice or three times daily—depends on the prescriber’s instructions.

Serious risks include severe skin reactions such as Stevens‑Johnson syndrome, mood changes like depression or suicidal thoughts, and rare blood disorders. Patients should seek immediate medical attention if they notice rash, mood swings, or signs of infection.

Levetiracetam is contraindicated in individuals with known hypersensitivity to the drug or any of its components. Caution is advised for patients with severe renal impairment, active psychiatric disorders, or those who are pregnant without a clear medical justification.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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