Product image of Levetiracetam Accord (Levetiracetam) supplied by GNH India

Levetiracetam Accord

Active Ingredient:
Levetiracetam
Origin:
EU

Levetiracetam Accord (Levetiracetam)

Levetiracetam, the active ingredient in Levetiracetam Accord, is an anticonvulsant presented as an oral formulation for oral use. It treats partial, generalized tonic‑clonic and myoclonic seizures in patients with epilepsy.
GNH India supplies Levetiracetam Accord as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Accord Healthcare Limited

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Indications & Clinical Uses

Levetiracetam is an anticonvulsant used to manage seizure disorders across several epilepsy syndromes.

  • Partial seizures: reduces seizure frequency in patients with focal onset seizures.
  • Generalized tonic‑clonic seizures: helps control convulsive episodes in generalized epilepsy.
  • Myoclonic seizures: diminishes rapid, involuntary muscle jerks associated with myoclonic epilepsy.

How It Works

  • Levetiracetam binds selectively to the synaptic vesicle protein SV2A, modulating neurotransmitter release and stabilising synaptic transmission. This action reduces neuronal hyper‑excitability and lowers the likelihood of seizure initiation without significant interaction with ion channels or metabolic enzymes.

Side Effects

Levetiracetam may cause a range of adverse reactions, most of which are mild to moderate.

Common Side Effects

  • Dizziness: transient sensation of light‑headedness.
  • Fatigue: feeling unusually tired or low in energy.
  • Somnolence: increased sleepiness during the day.
  • Irritability or mood changes: mild emotional fluctuations.

Serious or Rare Side Effects

  • Severe skin reactions: such as Stevens‑Johnson syndrome or toxic epidermal necrolysis.
  • Suicidal thoughts or behavior: new or worsening depression or suicidal ideation.
  • Blood dyscrasias: rare cases of agranulocytosis or thrombocytopenia.

Precautions & Warnings

Levetiracetam requires careful consideration in certain clinical situations.

  • Renal impairment: dose may need adjustment based on creatinine clearance.
  • History of psychiatric disorders: monitor for mood changes or suicidal ideation.
  • Elderly patients: start at lower doses and titrate slowly.
  • Concomitant antiepileptic therapy: assess for additive CNS effects.
  • Store at room temperature below 25°C: keep in the original pack, protect from moisture and direct sunlight.

Avoid Interactions

Levetiracetam has a low potential for drug‑drug interactions, but some combinations require attention.

Major Interactions (Avoid)

  • Strong enzyme inducers (e.g., carbamazepine, phenytoin, phenobarbital): may markedly reduce levetiracetam plasma levels.
  • Alcohol: can enhance central nervous system depression.

Moderate Interactions (Monitor Closely)

  • Oral contraceptives: efficacy may be decreased, requiring additional contraceptive measures.
  • Sedative agents (e.g., benzodiazepines, opioids): may increase sedation.
  • Drugs cleared renally: monitor renal function and adjust dosing as needed.

Frequently Asked Questions

Levetiracetam Accord contains levetiracetam, an anticonvulsant indicated for the treatment of partial seizures, generalized tonic‑clonic seizures, and myoclonic seizures in patients with epilepsy. It is prescribed by a qualified healthcare professional to help control seizure activity.

Levetiracetam binds to the synaptic vesicle protein SV2A, which modulates neurotransmitter release. This interaction reduces neuronal hyper‑excitability and stabilises synaptic transmission, thereby decreasing the likelihood of seizure generation.

The dosage of levetiracetam is individualized by the prescribing clinician based on the patient’s age, renal function, seizure type and response to therapy. The prescriber determines the appropriate strength, frequency and titration schedule.

Safety data for levetiracetam in pregnancy are limited, and the medication is classified as pregnancy category unknown. It should only be used if the potential benefit outweighs any risk. Breastfeeding mothers should discuss possible infant exposure with their healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Compared with many traditional antiepileptics, levetiracetam has a relatively simple pharmacokinetic profile, minimal protein binding and few drug‑enzyme interactions. It is often chosen for its broad spectrum of activity and lower risk of hepatic metabolism‑related adverse effects.

Store at room temperature below 25 °C in the original packaging, protected from moisture and direct sunlight. Keep the product out of reach of children and do not use if the packaging is damaged.

The medication is supplied as an oral formulation and is taken by mouth with or without food, as directed by the prescriber. Tablets should be swallowed whole and not chewed or crushed unless specifically advised.

Serious adverse reactions can include severe skin rashes such as Stevens‑Johnson syndrome, hypersensitivity reactions, suicidal thoughts or behaviors, and rare blood dyscrasias. Patients should seek immediate medical attention if they notice any of these symptoms.

Levetiracetam should not be used by individuals with a known hypersensitivity to levetiracetam or any of its excipients. Caution is advised in patients with severe renal impairment where dose adjustment may be required, and it should be prescribed only after a thorough clinical assessment.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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