Product image of Levetiracetam Actavis Group (Levetiracetam) supplied by GNH India

Levetiracetam Actavis Group

Active Ingredient:
Levetiracetam
Origin:
EU

Levetiracetam Actavis Group (Levetiracetam)

Levetiracetam, the active ingredient in Levetiracetam Actavis Group, is an anticonvulsant presented as an oral tablet for oral use. It is indicated for the treatment of partial seizures, generalized tonic‑clonic seizures and myoclonic seizures in adults and children.

GNH India supplies Levetiracetam Actavis Group as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, ensuring consistent quality and regulatory compliance across markets.

Manufacturer / TM Owner

Actavis Group Ptc Ehf.

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Indications & Clinical Uses

Levetiracetam is an anticonvulsant that treats seizure disorders.

  • Partial seizures: reduces the frequency of focal onset seizures in adults and children.
  • Generalized tonic‑clonic seizures: helps control bilateral convulsive episodes.
  • Myoclonic seizures: decreases sudden muscle jerks associated with juvenile myoclonic epilepsy.

How It Works

  • Levetiracetam binds to the synaptic vesicle protein SV2A, modulating neurotransmitter release and reducing neuronal excitability. This interaction stabilizes synaptic transmission without directly affecting ion channels, thereby diminishing the propagation of epileptic discharges across neuronal networks.

Side Effects

Levetiracetam may cause a range of adverse reactions, varying from mild to serious.

Common Side Effects

  • Dizziness: transient sensation of light‑headedness.
  • Fatigue: general feeling of tiredness.
  • Headache: mild to moderate pain in the head region.
  • Nausea: occasional upset stomach.
  • Irritability: mood changes or increased agitation.
  • Somnolence: drowsiness or sleepiness.

Serious or Rare Side Effects

  • Severe psychiatric reactions: depression, suicidal thoughts, or aggression.
  • Allergic reactions: rash, hives, or angioedema.
  • Hematologic abnormalities: rare cases of neutropenia or thrombocytopenia.
  • Stevens‑Johnson syndrome: severe skin blistering.
  • Hepatic dysfunction: elevated liver enzymes.
  • Anaphylaxis: life‑threatening systemic allergic response.

Precautions & Warnings

When prescribing levetiracetam, consider the following precautions to ensure safe use.

  • Renal impairment: adjust dose in patients with reduced kidney function.
  • Pregnancy: category B, use only if benefit outweighs risk.
  • Psychiatric symptoms: monitor for mood changes, depression, or aggression.
  • Concomitant CNS depressants: assess additive sedation.
  • Store at ambient temperature below 25°C: keep in the original pack, protect from moisture.

Avoid Interactions

Levetiracetam can interact with other medicines, affecting its efficacy or safety.

Major Interactions (Avoid)

  • Carbamazepine: may reduce levetiracetam plasma concentrations.
  • Phenobarbital: may decrease levetiracetam levels, reducing seizure control.

Moderate Interactions (Monitor Closely)

  • Valproic acid: may increase risk of adverse central nervous system effects.
  • Alcohol: may enhance sedation and dizziness.
  • Other antiepileptics: monitor for additive toxicity and adjust dosing as needed.

Frequently Asked Questions

Levetiracetam Actavis Group is an oral anticonvulsant indicated for the treatment of partial seizures, generalized tonic‑clonic seizures, and myoclonic seizures in both adult and pediatric patients. It helps reduce the frequency and severity of seizure episodes by stabilizing neuronal activity.

Levetiracetam exerts its effect by binding to the synaptic vesicle protein SV2A, which modulates neurotransmitter release. This action reduces neuronal excitability and limits the spread of epileptic discharges without directly influencing ion channels, providing seizure control across various seizure types.

The dosage of levetiracetam is individualized and determined by the prescribing healthcare professional based on the patient’s age, weight, renal function, and seizure type. Patients should follow the prescriber’s instructions and not adjust the dose without medical guidance.

Levetiracetam is classified as Pregnancy Category B, indicating that animal studies have not shown risk, but adequate human data are lacking. It may be used during pregnancy only if the potential benefit justifies the potential risk. Limited data suggest it is excreted in breast milk; breastfeeding decisions should be made with a physician.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams worldwide. After submission, the sales team will verify trade or institutional credentials and respond with pricing, availability, shipping details, and any necessary import documentation.

Compared with many traditional antiepileptics, levetiracetam has a distinct mechanism (SV2A binding) and a relatively favorable drug‑interaction profile. It does not induce hepatic enzymes, reducing the likelihood of interactions, and is generally well tolerated. However, individual response varies, and clinicians choose therapy based on seizure type, comorbidities, and patient tolerance.

Levetiracetam tablets should be stored at ambient temperature below 25 °C, protected from moisture and direct sunlight. Keep the product in its original packaging until use. Do not store in humid or excessively hot environments to maintain potency and stability.

Levetiracetam is administered orally, typically as tablets that can be swallowed whole with water. The dosage schedule (once, twice, or three times daily) is determined by the prescriber based on the patient’s clinical needs and renal function.

Serious adverse effects, though rare, include severe psychiatric reactions such as depression, suicidal ideation, aggression, and rare skin conditions like Stevens‑Johnson syndrome. Hematologic abnormalities like neutropenia may also occur. Patients should be monitored for mood changes, rash, or unexplained bruising and seek immediate medical attention if these arise.

Levetiracetam is contraindicated in patients with known hypersensitivity to levetiracetam or any of its excipients. Caution is advised for individuals with severe renal impairment, as dose adjustments are required. Pregnant or breastfeeding women should only use it when clearly indicated and after consulting a healthcare professional.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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