Product image of Levetiracetam Al (Levetiracetam) supplied by GNH India

Levetiracetam Al

Active Ingredient:
Levetiracetam
Origin:
EU

Levetiracetam Al (Levetiracetam)

Levetiracetam, the active ingredient in Levetiracetam Al, is an anticonvulsant presented as an oral tablet for systemic use. It is employed to control partial, generalized tonic‑clonic and myoclonic seizures in patients diagnosed with epilepsy and is approved across the European Union.

GNH India supplies Levetiracetam Al as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to EU GMP standards and provides regulatory documentation for import.

Manufacturer / TM Owner

Stadapharm Gmbh

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Indications & Clinical Uses

Levetiracetam is an antiepileptic medication used to manage seizure disorders.

  • Partial seizures: reduces frequency and severity of focal onset seizures.
  • Generalized tonic‑clonic seizures: helps prevent convulsive episodes.
  • Myoclonic seizures: diminishes rapid, involuntary muscle jerks associated with epilepsy.

How It Works

  • Levetiracetam binds to the synaptic vesicle protein SV2A, modulating neurotransmitter release and stabilizing neuronal membranes. This interaction reduces excessive neuronal firing and excitability, thereby decreasing the likelihood of seizure propagation across the central nervous system.

Side Effects

Levetiracetam is generally well tolerated, but adverse reactions can occur.

Common Side Effects

  • Dizziness: mild to moderate sensation of light‑headedness.
  • Fatigue: increased tiredness or lack of energy.
  • Somnolence: feeling unusually sleepy.
  • Headache: mild to moderate cranial pain.
  • Irritability: mood changes or increased agitation.
  • Nausea: occasional stomach upset.

Serious or Rare Side Effects

  • Severe allergic reactions: rash, swelling, or anaphylaxis.
  • Stevens‑Johnson syndrome: rare skin disorder with blistering.
  • Blood disorders: leukopenia or thrombocytopenia.
  • Mood changes: depression or suicidal thoughts.
  • Rash: widespread or severe dermatologic reactions.
  • Hepatic dysfunction: abnormal liver enzyme elevations.

Precautions & Warnings

Levetiracetam requires careful consideration of patient‑specific factors before use.

  • Renal impairment: dose may need adjustment based on creatinine clearance.
  • Hepatic impairment: monitor liver function tests periodically.
  • Pregnancy: safety not established; discuss risks with a healthcare professional.
  • Concomitant CNS depressants: may enhance sedation or dizziness.
  • Mood alterations: monitor for depression or suicidal ideation.
  • Discontinue abruptly: tapering is recommended to avoid seizure recurrence.
  • Store at ambient temperature: keep in original container, protect from moisture.

Avoid Interactions

Levetiracetam can interact with other medicines, affecting efficacy or safety.

Major Interactions (Avoid)

  • Carbamazepine: enzyme induction may lower levetiracetam levels.
  • Phenytoin: may reduce seizure control by increasing clearance.
  • Phenobarbital: can diminish therapeutic effect through hepatic induction.

Moderate Interactions (Monitor Closely)

  • Valproic acid: may increase risk of adverse CNS effects.
  • Fluconazole: potential for modest increase in levetiracetam concentration.
  • NSAIDs: monitor for enhanced sedation or dizziness.

Frequently Asked Questions

Levetiracetam Al is prescribed to treat epilepsy, specifically to reduce the frequency of partial seizures, generalized tonic‑clonic seizures, and myoclonic seizures in patients diagnosed with seizure disorders.

Levetiracetam binds to the synaptic vesicle protein SV2A, which modulates neurotransmitter release and stabilizes neuronal excitability. This action helps prevent the rapid, uncontrolled firing of neurons that leads to seizures.

The appropriate dose of levetiracetam is individualized by the prescribing clinician based on the patient’s age, weight, renal function, and seizure type. Dosage adjustments are made to achieve optimal seizure control while minimizing side effects.

Safety data for levetiracetam in pregnancy and lactation are limited. It is classified as pregnancy category unknown, so clinicians weigh potential benefits against risks. Women who are pregnant or nursing should discuss treatment options with their healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Compared with older agents such as carbamazepine or valproic acid, levetiracetam has a simpler pharmacokinetic profile, fewer drug‑enzyme interactions, and is generally well tolerated. However, individual response varies, and the choice of therapy depends on seizure type, comorbidities and patient preference.

Store the tablets at ambient temperature, below 25 °C, in the original packaging to protect them from moisture and light. Keep the container tightly closed and out of reach of children.

Levetiracetam Al is taken orally, with or without food, as directed by the prescriber. Tablets should be swallowed whole with water and not crushed or chewed unless specifically instructed.

Serious risks include severe allergic reactions such as Stevens‑Johnson syndrome, blood dyscrasias, significant mood changes including depression or suicidal thoughts, and rare hepatic dysfunction. Patients should seek immediate medical attention if they experience rash, fever, or mood disturbances.

Levetiracetam is contraindicated in individuals with known hypersensitivity to the drug or any of its components. Caution is advised for patients with severe renal impairment, uncontrolled psychiatric conditions, or those taking interacting enzyme‑inducing antiepileptics without proper monitoring.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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