Product image of Levetiracetam Alter (Levetiracetam) supplied by GNH India

Levetiracetam Alter

Active Ingredient:
Levetiracetam
Origin:
EU

Levetiracetam Alter (Levetiracetam)

Levetiracetam, the active ingredient in Levetiracetam Alter, is an antiepileptic presented as an oral dosage form for oral use. It is employed to control partial‑onset, generalized tonic‑clonic and myoclonic seizures in patients diagnosed with epilepsy across the European market.

GNH India supplies Levetiracetam Alter as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Alter S.A.

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Indications & Clinical Uses

  • Levetiracetam is an antiepileptic drug that modulates neuronal excitability to prevent seizure activity.
  • Partial‑onset seizures: reduces the frequency and severity of focal seizures.
  • Generalized tonic‑clonic seizures: helps achieve seizure freedom or significant reduction.
  • Myoclonic seizures: diminishes rapid, involuntary muscle jerks associated with epilepsy.

How It Works

  • Levetiracetam binds selectively to the synaptic vesicle protein SV2A, which regulates neurotransmitter release. This interaction modulates synaptic transmission, decreasing excessive neuronal firing and stabilising neuronal networks, thereby reducing the likelihood of seizure propagation.

Side Effects

Levetiracetam may cause a range of adverse reactions, most of which are mild to moderate.

Common Side Effects

  • Drowsiness: feeling unusually sleepy or fatigued.
  • Dizziness: sensation of light‑headedness or unsteadiness.
  • Headache: mild to moderate cranial pain.
  • Irritability: increased mood swings or agitation.
  • Nausea: upset stomach or feeling of queasiness.
  • Nasal congestion: blocked or runny nose.

Serious or Rare Side Effects

  • Severe allergic reaction: rash, swelling, or difficulty breathing.
  • Mood changes: depression, suicidal thoughts, or severe anxiety.
  • Blood disorders: low white blood cells or platelets.
  • Liver dysfunction: jaundice or abnormal liver enzymes.
  • Skin reactions: Stevens‑Johnson syndrome or toxic epidermal necrolysis.

Precautions & Warnings

  • Before initiating therapy, consider the following safety measures.
  • Renal function: dose may need adjustment in patients with impaired kidney function.
  • Pregnancy: discuss potential risks with a healthcare professional.
  • Concomitant CNS depressants: monitor for enhanced sedation.
  • Behavioral changes: observe for mood swings or depression.
  • Alcohol use: avoid excessive intake as it may increase dizziness.
  • Store at ambient temperature: keep below 25°C in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Levetiracetam can interact with other medicines, affecting efficacy or safety.

Major Interactions (Avoid)

  • Carbamazepine: may reduce levetiracetam plasma levels.
  • Phenobarbital: can lower levetiracetam concentrations.
  • Phenytoin: may decrease levetiracetam exposure.

Moderate Interactions (Monitor Closely)

  • Alcohol: may increase central nervous system depression.
  • Sedative antihistamines: can enhance drowsiness.
  • Opioids: monitor for additive respiratory depression.
  • Other antiepileptics: assess overall seizure control and side‑effect profile.

Frequently Asked Questions

Levetiracetam Alter is used to treat partial‑onset, generalized tonic‑clonic and myoclonic seizures in patients with epilepsy. It helps reduce seizure frequency and severity by stabilising neuronal activity.

Levetiracetam binds to the synaptic vesicle protein SV2A, modulating neurotransmitter release. This action decreases excessive neuronal firing, thereby lowering the risk of seizure propagation across the brain.

The specific dose of Levetiracetam Alter is determined by the prescribing clinician based on the patient’s age, weight, renal function and seizure type. Dosage adjustments are made to achieve optimal seizure control while minimising side effects.

Safety in pregnancy and lactation should be evaluated by a healthcare professional. Levetiracetam crosses the placenta and is excreted in breast milk, so the benefits and potential risks must be weighed before use.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Levetiracetam offers a distinct mechanism by targeting SV2A, which differs from sodium‑channel blockers like carbamazepine. It generally has fewer drug‑enzyme interactions, a favorable side‑effect profile, and can be used as monotherapy or adjunct therapy for various seizure types.

Store Levetiracetam Alter at ambient temperature, preferably below 25 °C. Keep the product in its original packaging, protect it from moisture and direct sunlight, and ensure the container is tightly closed to maintain stability.

Levetiracetam Alter is taken orally, usually with or without food. The tablet should be swallowed whole with water and not crushed or chewed unless specifically instructed by a healthcare provider.

Serious risks include severe allergic reactions, mood changes such as depression or suicidal thoughts, and rare blood disorders. Patients should seek immediate medical attention if they experience rash, swelling, mood disturbances, or signs of infection.

Levetiracetam Alter should be avoided in individuals with known hypersensitivity to levetiracetam or any of its excipients. Caution is also advised for patients with severe renal impairment unless dose adjustments are made under medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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