Product image of Levetiracetam Arrow Lab (Levetiracetam) supplied by GNH India

Levetiracetam Arrow Lab

Active Ingredient:
Levetiracetam
Origin:
EU

Levetiracetam Arrow Lab (Levetiracetam)

Levetiracetam, the active ingredient in Levetiracetam Arrow Lab, is an antiepileptic presented as an injectable solution for intravenous use. It is employed as adjunctive therapy for partial‑onset, myoclonic, and primary generalized tonic‑clonic seizures in patients who require additional seizure control.

GNH India supplies Levetiracetam Arrow Lab as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres, oncology centres, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Eugia Pharma (Malta) Ltd

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Indications & Clinical Uses

  • Levetiracetam is an antiepileptic indicated for several seizure types.
  • Partial‑onset seizures: reduces seizure frequency as adjunctive therapy.
  • Myoclonic seizures: provides adjunctive seizure control.
  • Primary generalized tonic‑clonic seizures: used as adjunctive therapy to decrease seizure occurrence.

How It Works

  • Levetiracetam binds to the synaptic vesicle protein SV2A, modulating neurotransmitter release and decreasing neuronal hyper‑excitability. This interaction stabilises synaptic transmission, thereby reducing the propagation of epileptic discharges without directly affecting ion channels or GABA receptors. The downstream effect includes inhibition of calcium‑dependent release of excitatory neurotransmitters, contributing to its anticonvulsant activity.

Side Effects

Levetiracetam may cause a range of adverse reactions, from mild to serious.

Common Side Effects

  • Dizziness: transient sensation of light‑headedness.
  • Somnolence: increased sleepiness or fatigue.
  • Irritability: mood changes or agitation.
  • Nausea: mild gastrointestinal upset.

Serious or Rare Side Effects

  • Severe skin reactions: such as Stevens‑Johnson syndrome or toxic epidermal necrolysis.
  • Psychiatric events: depression, suicidal thoughts, or aggressive behaviour.
  • Hematologic abnormalities: thrombocytopenia or severe allergic reactions.

Precautions & Warnings

  • When using Levetiracetam, several safety considerations are recommended.
  • Renal impairment: adjust dose based on creatinine clearance.
  • Psychiatric monitoring: watch for new or worsening mood changes.
  • Avoid abrupt discontinuation: taper under medical supervision to prevent seizure exacerbation.
  • Hepatic disease: use with caution in patients with liver dysfunction.
  • Hypersensitivity: discontinue if signs of allergic reaction appear.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Levetiracetam can interact with other medicines, requiring careful management.

Major Interactions (Avoid)

  • Strong enzyme inducers (e.g., carbamazepine, phenytoin): may lower levetiracetam plasma levels.
  • Other CNS depressants: can increase sedation and respiratory depression.
  • Drugs associated with severe skin reactions (e.g., lamotrigine): risk of overlapping cutaneous toxicity.

Moderate Interactions (Monitor Closely)

  • Additional antiepileptics: may necessitate dose adjustments for optimal seizure control.
  • Anticoagulants: potential increase in bleeding tendency.
  • Alcohol: may enhance dizziness and somnolence.

Frequently Asked Questions

Levetiracetam Arrow Lab is an intravenous antiepileptic indicated as adjunctive therapy for partial‑onset seizures, myoclonic seizures, and primary generalized tonic‑clonic seizures. It helps reduce seizure frequency when added to a patient’s existing seizure regimen.

Levetiracetam binds to the synaptic vesicle protein SV2A, which modulates neurotransmitter release. This reduces neuronal hyper‑excitability and stabilises synaptic transmission, thereby decreasing the likelihood of epileptic discharges without directly affecting ion channels or GABA receptors.

The specific dose of Levetiracetam Arrow Lab is determined by the prescribing clinician based on the patient’s age, weight, renal function, and seizure type. Healthcare professionals set the appropriate regimen and adjust it as needed.

Safety data for levetiracetam in pregnancy and lactation are limited. Clinicians should weigh potential benefits against possible risks and discuss options with the patient. Breastfeeding decisions should be made in consultation with a healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed) and import documentation.

Levetiracetam has a distinct mechanism (SV2A binding) and a relatively favorable interaction profile compared with many enzyme‑inducing antiepileptics. It is often preferred when clinicians seek a drug with minimal hepatic metabolism and fewer drug‑drug interactions, though individual response varies.

Levetiracetam Arrow Lab should be stored at 2‑8 °C, protected from light, and kept in its original container. Do not freeze or shake the solution. If temperature excursions occur, discard the product according to local regulations.

The product is supplied as an injectable solution for intravenous infusion. Administration is performed by qualified healthcare personnel, typically as a slow infusion over several minutes, following the dosing instructions provided by the prescriber.

Serious risks include severe skin reactions such as Stevens‑Johnson syndrome, psychiatric events like depression or suicidal thoughts, and rare hematologic abnormalities such as thrombocytopenia. Patients should be monitored closely for any of these signs.

Levetiracetam is contraindicated in individuals with known hypersensitivity to the drug or any of its excipients. Caution is advised in patients with severe renal impairment, uncontrolled psychiatric disorders, or those taking medications that may precipitate serious skin reactions.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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