Product image of Levetiracetam Aurobindo (Levetiracetam) supplied by GNH India

Levetiracetam Aurobindo

Active Ingredient:
Levetiracetam
Origin:
EU

Levetiracetam Aurobindo (Levetiracetam)

Levetiracetam, the active ingredient in Levetiracetam Aurobindo, is an anticonvulsant presented as an oral tablet for oral use. It treats partial seizures, generalized tonic‑clonic seizures and myoclonic seizures in patients with epilepsy.

GNH India supplies Levetiracetam Aurobindo as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Puren Pharma Gmbh & Co. Kg

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Indications & Clinical Uses

  • Levetiracetam is an antiepileptic medication used to control seizure activity.
  • Partial seizures: reduces the frequency and severity of focal seizures.
  • Generalized tonic‑clonic seizures: helps prevent convulsive episodes.
  • Myoclonic seizures: decreases myoclonic jerks.
  • Adjunct therapy for refractory epilepsy: used as add‑on when seizures are not fully controlled by other agents.

How It Works

  • Levetiracetam binds to the synaptic vesicle protein SV2A, modulating neurotransmitter release and stabilising neuronal membranes. This interaction reduces abnormal neuronal firing and lowers overall excitability in the central nervous system, thereby diminishing the likelihood of seizure propagation.

Side Effects

Levetiracetam may cause a range of adverse reactions.

Common Side Effects

  • Dizziness
  • Somnolence
  • Fatigue
  • Headache
  • Irritability
  • Nausea

Serious or Rare Side Effects

  • Severe allergic reactions (e.g., anaphylaxis)
  • Stevens‑Johnson syndrome or toxic epidermal necrolysis
  • Suicidal thoughts or behavior
  • Severe depression or mood changes
  • Rash or skin eruptions
  • Blood dyscrasias such as neutropenia or thrombocytopenia

Precautions & Warnings

  • When prescribing levetiracetam, consider the following safety measures.
  • Renal impairment: dose adjustment may be required.
  • Hepatic impairment: monitor liver function and adjust if needed.
  • Pregnancy: risk to fetus is unknown; use only if benefits outweigh risks.
  • Concomitant CNS depressants: may increase sedation or dizziness.
  • Driving and operating machinery: patients should be cautioned about possible impairment.
  • Store at room temperature: keep in the original packaging, protect from moisture and heat.

Avoid Interactions

Levetiracetam can interact with several medicines; awareness helps avoid reduced efficacy or increased toxicity.

Major Interactions (Avoid)

  • Carbamazepine: may lower levetiracetam plasma levels.
  • Phenytoin: can reduce levetiracetam exposure.
  • Phenobarbital: may decrease levetiracetam concentrations.

Moderate Interactions (Monitor Closely)

  • Alcohol: may enhance central nervous system depression.
  • Other antiepileptics: additive effects on seizure control and side‑effect profile.
  • Antidepressants: potential increase in irritability or mood changes.

Frequently Asked Questions

Levetiracetam Aurobindo is an antiepileptic drug indicated for the treatment of partial seizures, generalized tonic‑clonic seizures, and myoclonic seizures in patients with epilepsy. It helps reduce the frequency and severity of seizure episodes when prescribed by a qualified healthcare professional.

Levetiracetam works by binding to the synaptic vesicle protein SV2A, which modulates neurotransmitter release. This action stabilises neuronal membranes and reduces abnormal neuronal excitability, thereby decreasing the likelihood of seizure initiation and propagation.

The dosage of levetiracetam is individualized and set by the prescribing clinician based on the patient’s age, weight, renal function, and seizure type. Patients should follow the exact dosing instructions provided by their healthcare provider and not adjust the dose on their own.

The safety of levetiracetam in pregnancy and lactation is not fully established. It should only be used if the potential benefit to the mother outweighs any possible risk to the fetus or infant. Women who are pregnant, planning pregnancy, or breastfeeding should discuss alternatives and monitoring strategies with their physician.

To order Levetiracetam Aurobindo, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, and will request trade or institutional credentials before providing pricing, availability, shipping details and any necessary import documentation.

Levetiracetam is distinguished by its unique SV2A binding mechanism, which generally results in fewer drug‑drug interactions compared with enzyme‑inducing agents such as carbamazepine or phenytoin. It is often chosen for its broad spectrum of activity across seizure types and its relatively favorable tolerability profile.

Levetiracetam tablets should be stored at room temperature, below 25 °C, in the original container to protect them from moisture and light. Keep the product out of reach of children and avoid storing in humid or excessively hot environments.

Levetiracetam is taken orally, usually as a tablet or oral solution, with or without food. The exact administration schedule—once daily, twice daily, or more—depends on the prescriber’s recommendation and the individual patient’s therapeutic needs.

Serious risks include severe allergic reactions such as anaphylaxis, skin conditions like Stevens‑Johnson syndrome, and neuropsychiatric events such as suicidal thoughts, severe depression, or aggressive behaviour. Patients should seek immediate medical attention if they experience any of these symptoms.

Levetiracetam is contraindicated in individuals with known hypersensitivity to the drug or any of its excipients. Caution is also advised for patients with severe renal impairment, as dose adjustments are required, and for those with a history of serious psychiatric disorders.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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