Product image of Levetiracetam Aurobindo (Levetiracetam) supplied by GNH India

Levetiracetam Aurobindo

Active Ingredient:
Levetiracetam
Origin:
EU

Levetiracetam Aurobindo (Levetiracetam)

Levetiracetam, the active ingredient in Levetiracetam Aurobindo, is an anticonvulsant presented as an oral dosage form for oral use. It is employed to treat various seizure types in patients with epilepsy, including partial, generalized tonic‑clonic, and myoclonic seizures.

GNH India supplies Levetiracetam Aurobindo as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, providing quality‑assured products that meet EU regulatory standards.

Manufacturer / TM Owner

Generis Farmacêutica, S.A.

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Indications & Clinical Uses

  • Levetiracetam is an antiepileptic drug that reduces abnormal neuronal firing in the brain, helping control seizure activity.
  • Partial seizures: decreases frequency and severity of focal seizures.
  • Generalized tonic‑clonic seizures: helps prevent convulsive episodes.
  • Myoclonic seizures: reduces rapid, involuntary muscle jerks.

How It Works

  • Levetiracetam binds to the synaptic vesicle protein SV2A, modulating neurotransmitter release and stabilizing neuronal membranes. This interaction reduces excessive neuronal excitability, thereby diminishing the propagation of seizure activity across neural networks.

Side Effects

Levetiracetam may cause a range of adverse reactions, from mild to severe.

Common Side Effects

  • Dizziness
  • Fatigue
  • Headache
  • Somnolence
  • Nausea
  • Irritability

Serious or Rare Side Effects

  • Severe allergic reactions (e.g., Stevens‑Johnson syndrome)
  • Mood changes including depression or suicidal thoughts
  • Hematologic abnormalities (e.g., neutropenia)
  • Severe skin rash
  • Hepatic dysfunction
  • Respiratory depression when combined with other CNS depressants

Precautions & Warnings

  • Before initiating therapy, consider the following safety measures.
  • Renal impairment: dose adjustment may be required based on renal function.
  • Mood monitoring: observe for depression, anxiety, or suicidal ideation.
  • Drug discontinuation: avoid abrupt cessation to reduce seizure recurrence.
  • Pregnancy: risk unknown; use only if benefit outweighs potential risk.
  • Drug interactions: review concomitant medications for potential interactions.
  • Store below 25°C: keep in the original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Levetiracetam can interact with several medicines; awareness helps maintain therapeutic effectiveness.

Major Interactions (Avoid)

  • Carbamazepine: may lower levetiracetam plasma concentrations.
  • Phenytoin: can reduce levetiracetam levels.
  • Rifampin: induces metabolism, decreasing drug exposure.

Moderate Interactions (Monitor Closely)

  • Valproic acid: may increase levetiracetam concentrations.
  • Other CNS depressants: additive sedation or respiratory depression.
  • Alcohol: enhances central nervous system effects.

Frequently Asked Questions

Levetiracetam Aurobindo is prescribed to manage epilepsy. It is effective for partial (focal) seizures, generalized tonic‑clonic seizures, and myoclonic seizures, helping to reduce the frequency and severity of these seizure types in patients of various ages.

Levetiracetam binds to the synaptic vesicle protein SV2A, a key regulator of neurotransmitter release. This binding modulates synaptic transmission, stabilizes neuronal membranes, and lowers excessive neuronal excitability, which together help prevent the spread of seizure activity.

The dosage of Levetiracetam Aurobindo is individualized. A qualified prescriber determines the appropriate dose based on the patient’s age, weight, renal function, seizure type, and response to therapy. Patients should follow the prescribing information provided by their healthcare professional.

Safety data for levetiracetam during pregnancy and lactation are limited. The drug should only be used when the potential benefit to the mother outweighs any possible risk to the fetus or infant. Healthcare providers will assess each case and discuss alternatives if necessary.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

Compared with older agents such as carbamazepine or valproic acid, levetiracetam has a relatively simple pharmacokinetic profile, fewer drug‑enzyme interactions, and does not require routine therapeutic drug monitoring. However, individual response varies, and clinicians consider seizure type, comorbidities and tolerability when selecting therapy.

Levetiracetam Aurobindo should be stored at or below 25 °C (77 °F). Keep the product in its original container, protect it from moisture and direct sunlight, and ensure the packaging remains sealed until use to maintain potency.

The medication is administered orally, with or without food, as directed by the prescriber. Tablets (or the appropriate oral dosage form) should be swallowed whole with water. Patients should not crush or chew the tablets unless specifically instructed.

Serious adverse events include severe allergic reactions such as Stevens‑Johnson syndrome, marked skin rash, hematologic abnormalities, and significant mood changes including depression or suicidal thoughts. Any sudden or severe symptoms should prompt immediate medical evaluation.

Individuals with a known hypersensitivity to levetiracetam or any of its excipients should avoid the product. Patients with severe renal impairment may require dose adjustment or alternative therapy, and the drug should be used with caution in those with a history of mood disorders.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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