Product image of Levetiracetam Aurobindo (Levetiracetam) supplied by GNH India

Levetiracetam Aurobindo

Active Ingredient:
Levetiracetam
Origin:
EU

Levetiracetam Aurobindo (Levetiracetam)

Levetiracetam, the active ingredient in Levetiracetam Aurobindo, is an anticonvulsant presented as a tablet for oral use. It is indicated for the control of partial seizures, generalized tonic‑clonic seizures and myoclonic seizures in patients diagnosed with epilepsy, and is marketed across the European Union.

GNH India supplies Levetiracetam Aurobindo as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, providing reliable sourcing for generic antiepileptic medicines. The company adheres to stringent quality standards and offers global logistics support.

Manufacturer / TM Owner

Aurobindo Pharma (Malta) Limited

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Indications & Clinical Uses

  • Levetiracetam is an antiepileptic agent used to manage seizure disorders.
  • Partial seizures: reduces the frequency of focal onset seizures.
  • Generalized tonic‑clonic seizures: helps achieve seizure control in primary generalized seizures.
  • Myoclonic seizures: decreases occurrence of myoclonic jerks in appropriate patients.

How It Works

  • Levetiracetam binds selectively to the synaptic vesicle protein SV2A, modulating neurotransmitter release and stabilizing neuronal membranes. This interaction reduces excessive neuronal firing and diminishes the propagation of seizure activity throughout the central nervous system.

Side Effects

Levetiracetam may cause a range of adverse reactions, which are categorized by frequency and severity.

Common Side Effects

  • Drowsiness: feeling unusually sleepy or fatigued.
  • Dizziness: light‑headed sensation, especially when standing quickly.
  • Headache: mild to moderate cranial pain.
  • Irritability: increased agitation or mood swings.

Serious or Rare Side Effects

  • Severe allergic reactions: rash, swelling, or Stevens‑Johnson syndrome.
  • Mood changes: depression, suicidal thoughts, or aggressive behavior.
  • Hematologic abnormalities: neutropenia or thrombocytopenia.

Precautions & Warnings

  • Before initiating therapy, clinicians should consider several safety aspects.
  • Renal impairment: dose may need adjustment in patients with reduced kidney function.
  • Pregnancy: category B, use only if benefit outweighs risk.
  • Psychiatric symptoms: monitor for mood changes, depression, or aggression.
  • Concomitant CNS depressants: may enhance sedation.
  • Drug interactions: review concomitant medications for potential interactions.
  • Store at ambient temperature: keep in original container, protect from moisture and light.

Avoid Interactions

Levetiracetam can interact with other medicines, requiring attention to the level of risk.

Major Interactions (Avoid)

  • Carbamazepine: may reduce levetiracetam plasma concentrations, decreasing efficacy.
  • Phenobarbital: may lower levetiracetam levels and compromise seizure control.

Moderate Interactions (Monitor Closely)

  • Valproic acid: may increase risk of central nervous system adverse effects.
  • Alcohol: can potentiate sedation and dizziness.
  • Other antiepileptics (e.g., phenytoin): monitor seizure control and adjust therapy as needed.

Frequently Asked Questions

Levetiracetam Aurobindo is a generic antiepileptic medication prescribed to control partial seizures, generalized tonic‑clonic seizures and myoclonic seizures in patients with epilepsy. It helps reduce the frequency and severity of seizure episodes when taken as directed by a healthcare professional.

Levetiracetam binds to the synaptic vesicle protein SV2A in the brain, which modulates neurotransmitter release. This action stabilizes neuronal activity, lowers excessive excitability, and prevents the rapid spread of electrical discharges that cause seizures.

The specific dose of Levetiracetam Aurobindo is individualized by the prescribing clinician based on the patient’s age, weight, type of seizure, renal function and response to therapy. Patients should follow the exact dosing instructions provided by their healthcare provider.

Levetiracetam is classified as pregnancy category B, indicating that animal studies have not shown risk but there are limited human data. It may be used during pregnancy only if the potential benefit justifies any potential risk. Small amounts are excreted in breast milk; breastfeeding decisions should be made with a physician’s guidance.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain needs) and the necessary import documentation.

Compared with older agents such as carbamazepine or valproate, levetiracetam has a relatively simple pharmacokinetic profile, fewer drug‑enzyme interactions, and does not require routine blood‑level monitoring. However, individual response varies, and some patients may experience behavioral changes that are less common with other drugs.

Levetiracetam tablets should be stored at ambient temperature, below 25 °C, in the original packaging to protect them from moisture and light. Keep the product out of reach of children and avoid storing in bathrooms or other humid environments.

Levetiracetam Aurobindo is taken orally, usually as a tablet swallowed whole with a glass of water. It can be taken with or without food, but patients should follow the timing and frequency prescribed by their clinician to maintain consistent blood levels.

Serious adverse reactions, although rare, include severe allergic skin reactions such as Stevens‑Johnson syndrome, significant mood changes like depression or suicidal thoughts, and hematologic disorders such as neutropenia. Patients should seek immediate medical attention if they notice rash, mood swings, or signs of infection.

Levetiracetam is contraindicated in individuals with a known hypersensitivity to levetiracetam or any of its excipients. Caution is advised for patients with severe renal impairment, as dose adjustment may be required, and for those with a history of psychiatric disorders who may be more susceptible to mood‑related side effects.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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