Product image of Levetiracetam Axcount (Levetiracetam) supplied by GNH India

Levetiracetam Axcount

Active Ingredient:
Levetiracetam
Origin:
EU

Levetiracetam Axcount (Levetiracetam)

Levetiracetam, the active ingredient in Levetiracetam Axcount, is an antiepileptic presented as an oral tablet for systemic use. It is indicated for the treatment of partial, generalized tonic‑clonic and myoclonic seizures in both adult and pediatric patients.

GNH India supplies Levetiracetam Axcount as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides reliable logistics for global distribution. Our network ensures timely delivery and regulatory compliance across EU and other markets.

Manufacturer / TM Owner

Axcount Generika Gmbh

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Indications & Clinical Uses

Levetiracetam is an antiepileptic drug that reduces neuronal excitability in seizure disorders.

  • Partial seizures: reduces frequency of focal onset seizures.
  • Generalized tonic‑clonic seizures: helps control convulsive episodes.
  • Myoclonic seizures: diminishes rapid muscle jerks associated with the condition.

How It Works

  • Levetiracetam binds to the synaptic vesicle protein SV2A, a key regulator of neurotransmitter release. This interaction modulates calcium‑dependent exocytosis, stabilizing neuronal membranes and decreasing hyper‑synchronised firing. By reducing the release of excitatory neurotransmitters, the drug lowers neuronal excitability and helps prevent the initiation and propagation of epileptic discharges.

Side Effects

Levetiracetam may cause a range of adverse reactions, varying from mild to serious.

Common Side Effects

  • Fatigue
  • Dizziness
  • Somnolence
  • Headache
  • Irritability
  • Nausea

Serious or Rare Side Effects

  • Severe allergic reactions such as Stevens‑Johnson syndrome
  • Mood changes including depression or suicidal thoughts
  • Rash or skin eruptions
  • Blood dyscrasias (e.g., leukopenia, thrombocytopenia)
  • Respiratory depression
  • Multi‑organ hypersensitivity syndrome

Precautions & Warnings

When prescribing Levetiracetam, clinicians should consider several safety measures.

  • Dose adjustment in renal impairment: assess creatinine clearance before prescribing.
  • Monitor psychiatric symptoms: watch for depression, anxiety or agitation.
  • Avoid abrupt discontinuation: taper under medical supervision to prevent seizure exacerbation.
  • Use cautiously in patients with hepatic dysfunction: limited data are available.
  • Store at ambient temperature: keep in the original container, protect from moisture and light.

Avoid Interactions

Levetiracetam can interact with other medicines, influencing its effectiveness or safety.

Major Interactions (Avoid)

  • Concomitant use with carbamazepine: may reduce levetiracetam plasma levels.
  • Co‑administration with enzyme‑inducing antiepileptics (e.g., phenytoin, phenobarbital): may decrease efficacy.
  • Combination with strong CYP3A4 inhibitors (e.g., ketoconazole): limited data, monitor levels.

Moderate Interactions (Monitor Closely)

  • Concurrent use with other antiepileptics (e.g., valproate): may increase side‑effect risk.
  • Alcohol consumption: may enhance central nervous system depression.
  • Use with oral contraceptives: may slightly reduce contraceptive effectiveness.

Frequently Asked Questions

Levetiracetam Axcount is used to treat several types of epilepsy, including partial seizures, generalized tonic‑clonic seizures and myoclonic seizures. It helps reduce the frequency and severity of seizure episodes in both adults and children when prescribed by a qualified healthcare professional.

Levetiracetam binds to the synaptic vesicle protein SV2A, which plays a crucial role in the release of neurotransmitters. This binding modulates calcium‑dependent exocytosis, stabilising neuronal membranes and lowering the likelihood of excessive neuronal firing that leads to seizures.

The appropriate dose of Levetiracetam Axcount is determined by the prescribing clinician based on the patient’s age, weight, renal function and seizure type. Dosage adjustments may be required for special populations, and the regimen should always follow the prescriber’s instructions.

Safety data for levetiracetam in pregnancy and lactation are limited. The prescriber will weigh potential benefits against possible risks to the fetus or infant. Women who are pregnant, planning pregnancy, or breastfeeding should discuss treatment options with their healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, and will request verification of trade or institutional credentials before providing pricing, availability, shipping details and any necessary import documentation.

Levetiracetam differs from many traditional antiepileptics because it does not act through major cytochrome P450 enzymes, resulting in fewer drug‑drug interactions. Its unique SV2A binding provides effective seizure control with a generally favorable tolerability profile compared with older agents such as carbamazepine or phenytoin.

Levetiracetam Axcount should be stored at ambient temperature, below 25 °C. Keep the tablets in their original packaging, protect them from moisture and direct sunlight, and ensure the container is tightly closed to maintain product stability.

Levetiracetam Axcount is taken orally, usually with or without food, as directed by the prescriber. Tablets are swallowed whole with a glass of water. The exact frequency and timing depend on the individual treatment plan established by the healthcare professional.

Serious risks include severe allergic reactions such as Stevens‑Johnson syndrome, significant mood changes like depression or suicidal thoughts, and rare blood disorders. Patients should seek immediate medical attention if they experience rash, swelling, mood alterations, or signs of infection.

Levetiracetam is contraindicated in individuals with known hypersensitivity to levetiracetam or any of its excipients. Caution is advised for patients with severe renal impairment, uncontrolled psychiatric conditions, or those taking interacting medications that may diminish its effectiveness.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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