Product image of Levetiracetam Crescent (Levetiracetam) supplied by GNH India

Levetiracetam Crescent

Active Ingredient:
Levetiracetam
Origin:
EU

Levetiracetam Crescent (Levetiracetam)

Levetiracetam, the active ingredient in Levetiracetam Crescent, is an anticonvulsant presented as a tablet for oral use. It treats partial, generalized tonic‑clonic and myoclonic seizures in patients with epilepsy.

GNH India supplies Levetiracetam Crescent as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Crescent Pharma Limited

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Indications & Clinical Uses

  • Levetiracetam is an antiepileptic medication used to control seizure activity across several seizure types.
  • Partial seizures: reduces the frequency of focal onset seizures.
  • Generalized tonic‑clonic seizures: helps prevent convulsive episodes.
  • Myoclonic seizures: decreases the occurrence of rapid muscle jerks.

How It Works

  • Levetiracetam binds to the synaptic vesicle protein SV2A, modulating neurotransmitter release and stabilising neuronal membranes. This action reduces abnormal neuronal firing and diminishes the propagation of seizure activity throughout the central nervous system.

Side Effects

Levetiracetam may cause a range of adverse reactions, most of which are mild and reversible.

Common Side Effects

  • Dizziness
  • Somnolence
  • Fatigue
  • Headache
  • Irritability
  • Nausea

Serious or Rare Side Effects

  • Severe allergic reactions such as anaphylaxis
  • Stevens‑Johnson syndrome or toxic epidermal necrolysis
  • Blood dyscrasias (e.g., neutropenia, thrombocytopenia)
  • Suicidal thoughts or behaviour
  • Severe skin rash
  • Multi‑organ hypersensitivity reactions

Precautions & Warnings

When prescribing or dispensing levetiracetam, several safety considerations should be observed.

  • Renal impairment: dose adjustment may be required based on renal function.
  • Hepatic dysfunction: monitor liver enzymes and clinical status.
  • Pregnancy: safety category unknown; weigh potential benefits against risks.
  • Concomitant CNS depressants: may increase sedation or respiratory depression.
  • Behavioral changes: monitor for mood swings, aggression, or depression.
  • Store at ambient temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Levetiracetam can interact with other medicines, affecting its efficacy or safety.

Major Interactions (Avoid)

  • Carbamazepine: may lower levetiracetam plasma concentrations.
  • Phenobarbital: may reduce levetiracetam levels.
  • Phenytoin: may decrease levetiracetam exposure.

Moderate Interactions (Monitor Closely)

  • Alcohol: additive central nervous system depression.
  • Other CNS depressants (e.g., benzodiazepines, opioids): increased sedation risk.
  • Fluconazole: may raise levetiracetam concentrations.

Frequently Asked Questions

Levetiracetam Crescent is an oral antiepileptic medication indicated for the treatment of partial seizures, generalized tonic‑clonic seizures, and myoclonic seizures in patients diagnosed with epilepsy.

Levetiracetam binds to the synaptic vesicle protein SV2A, which modulates neurotransmitter release. This action stabilises neuronal excitability and reduces the likelihood of seizure propagation.

The appropriate dose is determined by the prescribing clinician based on the patient’s age, weight, renal function, and seizure type. Dosage regimens are individualized and should follow the prescriber’s instructions.

The pregnancy safety category for levetiracetam is not definitively established. Use during pregnancy or lactation only if the potential benefit justifies the potential risk, and decisions should be made in consultation with a healthcare professional.

Enquiries can be submitted via the product page on gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Levetiracetam offers a distinct mechanism by targeting SV2A, which differs from sodium‑channel blockers like carbamazepine. It generally has fewer drug‑enzyme interactions, a favorable tolerability profile, and does not require routine therapeutic drug monitoring.

Store the tablets at ambient temperature, below 25 °C, in the original packaging. Protect them from moisture, excessive heat and direct sunlight to maintain product stability.

Levetiracetam Crescent is taken orally, usually with or without food, as directed by the prescriber. Tablets should be swallowed whole with water and not chewed or crushed unless specifically advised.

Serious risks include severe allergic reactions such as anaphylaxis, life‑threatening skin conditions like Stevens‑Johnson syndrome, blood dyscrasias, and the emergence of suicidal thoughts or behaviours. Patients should seek immediate medical attention if any of these occur.

Patients with known hypersensitivity to levetiracetam or any of its excipients should avoid the product. Caution is also advised for individuals with severe renal impairment, uncontrolled psychiatric disorders, or those taking interacting medications without proper monitoring.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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