Product image of Levetiracetam Eignapharma (Levetiracetam) supplied by GNH India

Levetiracetam Eignapharma

Active Ingredient:
Levetiracetam
Origin:
EU

Levetiracetam Eignapharma (Levetiracetam)

Levetiracetam, the active ingredient in Levetiracetam Eignapharma, is an anticonvulsant presented as an injectable solution for intravenous use. It is employed as adjunctive therapy to control partial‑onset, generalized tonic‑clonic and myoclonic seizures in patients requiring additional seizure management.

GNH India supplies Levetiracetam Eignapharma as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Eignapharma Slu

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Indications & Clinical Uses

Levetiracetam is an antiepileptic drug that acts on seizure activity across several seizure types.

  • Partial‑onset seizures: used as adjunctive therapy to reduce seizure frequency.
  • Generalized tonic‑clonic seizures: used as adjunctive therapy to help achieve better seizure control.
  • Myoclonic seizures: used as adjunctive therapy to decrease the number of seizure episodes.

How It Works

  • Levetiracetam binds selectively to the synaptic vesicle protein SV2A, modulating neurotransmitter release and stabilizing neuronal membranes. This interaction reduces excessive neuronal firing and hyperexcitability, thereby diminishing the likelihood of seizure propagation without significant effects on ion channels or GABA receptors.

Side Effects

Levetiracetam may be associated with a range of adverse reactions, varying from mild to serious.

Common Side Effects

  • Fatigue: feeling of tiredness or lack of energy.
  • Dizziness: sensation of light‑headedness or unsteadiness.
  • Somnolence: increased sleepiness during the day.
  • Headache: mild to moderate head pain.
  • Irritability: mood changes including agitation.
  • Nausea: feeling of stomach upset.

Serious or Rare Side Effects

  • Stevens‑Johnson syndrome: severe skin reaction requiring immediate medical attention.
  • Suicidal ideation: thoughts of self‑harm that must be reported promptly.
  • Severe depression: marked mood disturbances that may need psychiatric evaluation.
  • Anaphylaxis: acute allergic reaction with breathing difficulty.
  • Blood dyscrasias: rare blood cell abnormalities such as leukopenia.

Precautions & Warnings

When prescribing levetiracetam, several safety considerations should be observed.

  • Renal impairment: adjust dosage according to renal function as recommended by the prescriber.
  • Hepatic impairment: monitor liver function tests periodically.
  • Pregnancy: category B; use only if the potential benefit justifies the potential risk to the fetus.
  • Concomitant CNS depressants: observe for enhanced sedation or respiratory depression.
  • Psychiatric symptoms: watch for mood changes, depression, or suicidal thoughts.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Levetiracetam can interact with other medicines; awareness of the interaction level guides clinical decisions.

Major Interactions (Avoid)

  • Carbamazepine: may lower levetiracetam plasma concentrations, reducing efficacy.
  • Phenobarbital or phenytoin: enzyme‑inducing antiepileptics can decrease levetiracetam levels.
  • Strong CYP450 inhibitors: although levetiracetam is minimally metabolized, monitor for unexpected changes.

Moderate Interactions (Monitor Closely)

  • CNS depressants (e.g., benzodiazepines, alcohol): may increase sedation and respiratory depression.
  • Other antiepileptic drugs: dose adjustments may be required to maintain seizure control.
  • Hormonal contraceptives: levetiracetam may reduce contraceptive effectiveness; consider alternative methods.

Frequently Asked Questions

Levetiracetam Eignapharma is an injectable antiepileptic indicated as adjunctive therapy for partial‑onset seizures, generalized tonic‑clonic seizures, and myoclonic seizures. It is prescribed when additional seizure control is needed alongside other antiseizure medications.

Levetiracetam binds to the synaptic vesicle protein SV2A, which modulates neurotransmitter release. This action stabilizes neuronal firing and reduces hyperexcitability, helping to prevent the spread of seizure activity without directly affecting ion channels or GABA receptors.

The dosing regimen for Levetiracetam Eignapharma is individualized. A qualified prescriber determines the appropriate dose and infusion rate based on the patient’s age, weight, renal function, and clinical response, following local prescribing guidelines.

Levetiracetam is classified as pregnancy category B, indicating that animal studies have not shown risk and there are no adequate human studies. It may be used during pregnancy if the potential benefit outweighs the risk. Small amounts are excreted in breast milk; breastfeeding decisions should be made with a healthcare professional.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain where applicable) and necessary import documentation.

Compared with older antiepileptics such as carbamazepine or phenytoin, levetiracetam has a more favorable drug‑interaction profile, requires no routine therapeutic drug monitoring, and is generally well tolerated. However, individual response varies, and selection should consider seizure type, comorbidities, and patient‑specific factors.

Levetiracetam Eignapharma must be stored at 2‑8 °C in a refrigerator. Keep the vial in its original packaging, protect it from light, and avoid freezing or shaking the solution. If temperature excursions occur, discard the product according to local regulations.

The product is administered intravenously. It can be given as a slow infusion over 15 minutes or as a bolus, depending on clinical judgment and institutional protocols. Administration should be performed by qualified healthcare personnel in a setting equipped for intravenous therapy.

Serious adverse events include severe skin reactions such as Stevens‑Johnson syndrome, suicidal thoughts or behavior, severe depression, anaphylaxis, and rare blood disorders. Patients should be instructed to seek immediate medical attention if they notice rash, mood changes, or signs of an allergic reaction.

Levetiracetam is contraindicated in individuals with known hypersensitivity to levetiracetam or any of the formulation excipients. Patients with severe renal impairment must have dose adjustments; without appropriate adjustment, use is not recommended. Caution is also advised in patients with a history of psychiatric disorders.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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