Product image of Levetiracetam Eignapharma (Levetiracetam) supplied by GNH India

Levetiracetam Eignapharma

Active Ingredient:
Levetiracetam
Origin:
EU

Levetiracetam Eignapharma (Levetiracetam)

Levetiracetam, the active ingredient in Levetiracetam Eignapharma, is an anticonvulsant presented as an injection for intravenous use. It treats epilepsy, including partial‑onset seizures and generalized tonic‑clonic seizures, in adults and children as prescribed, offering a rapid onset of action for acute seizure control.

GNH India supplies Levetiracetam Eignapharma as a licensed, GDP‑compliant international pharmaceutical supplier, providing the product to hospitals, pharmacies, and clinics across Europe, Asia, Africa and the Americas, ensuring consistent quality and regulatory compliance for global healthcare providers.

Manufacturer / TM Owner

Eignapharma Slu

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Indications & Clinical Uses

  • Levetiracetam is an antiepileptic drug used to manage seizure disorders by stabilizing neuronal activity.
  • Epilepsy: reduces overall seizure frequency in patients with generalized or focal epilepsy.
  • Partial‑onset seizures: controls focal seizure activity and prevents progression.
  • Generalized tonic‑clonic seizures: helps prevent convulsive episodes in patients with this seizure type.

How It Works

  • Levetiracetam binds to the synaptic vesicle protein SV2A, a key regulator of neurotransmitter release. This interaction modulates calcium‑dependent exocytosis, decreasing the release of excitatory neurotransmitters and stabilizing neuronal firing. By reducing neuronal hyper‑excitability, the drug lowers the likelihood of seizure initiation and propagation without significant effects on G‑protein‑coupled receptors or ion channels. The precise downstream pathways remain under investigation, but the net effect is a dampening of abnormal cortical synchrony.

Side Effects

Levetiracetam may cause a range of adverse reactions, which are categorized by frequency and severity.

Common Side Effects

  • Dizziness
  • Fatigue
  • Somnolence
  • Headache
  • Irritability
  • Nausea

Serious or Rare Side Effects

  • Severe allergic reactions such as anaphylaxis or angioedema
  • Stevens‑Johnson syndrome or toxic epidermal necrolysis
  • Blood dyscrasias including neutropenia or thrombocytopenia
  • Suicidal thoughts or behavior
  • Severe skin rash
  • Rare respiratory depression

Precautions & Warnings

  • When prescribing Levetiracetam, clinicians should consider several safety precautions to optimize therapy and minimize risk.
  • Renal impairment: dose adjustment may be required based on creatinine clearance.
  • Hepatic dysfunction: monitor liver function tests periodically.
  • Concomitant CNS depressants: increased sedation risk, monitor patient response.
  • Pregnancy: potential unknown risks; discuss benefits and alternatives with the patient.
  • Driving and operating machinery: may cause drowsiness; advise caution.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Levetiracetam can interact with other medicines, influencing its plasma concentration or enhancing side‑effects.

Major Interactions (Avoid)

  • Carbamazepine: enzyme induction reduces levetiracetam levels.
  • Phenytoin: may lower levetiracetam exposure.
  • Phenobarbital: can decrease therapeutic concentration.

Moderate Interactions (Monitor Closely)

  • Valproic acid: may increase levetiracetam plasma levels.
  • Topiramate: additive CNS depression possible.
  • Alcohol: enhances sedative effects, monitor for excessive drowsiness.

Frequently Asked Questions

Levetiracetam Eignapharma is an injectable antiepileptic medication indicated for the treatment of epilepsy, specifically for controlling partial‑onset seizures and generalized tonic‑clonic seizures in both adult and pediatric patients as determined by a qualified healthcare professional.

Levetiracetam exerts its effect by binding to the synaptic vesicle protein SV2A, which modulates neurotransmitter release. This reduces excessive neuronal firing and stabilizes brain activity, thereby decreasing the likelihood of seizure initiation and spread.

The appropriate dose of Levetiracetam Eignapharma is individualized and set by the prescribing clinician based on the patient’s age, weight, renal function, seizure type, and response to therapy. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

Safety data for levetiracetam in pregnancy and lactation are limited. The medication should only be used if the potential benefit to the mother outweighs any possible risk to the fetus or infant. Women who are pregnant, planning pregnancy, or breastfeeding should discuss treatment options with their healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams worldwide, and will request trade or institutional credentials before providing pricing, availability, shipping details (including cold‑chain where applicable), and import documentation.

Levetiracetam offers a favorable safety profile and minimal drug‑enzyme interactions compared with many older antiepileptics such as carbamazepine or phenytoin. It is often chosen for patients who require rapid intravenous control of seizures or who have experienced adverse effects with alternative agents.

Levetiracetam injection should be stored at 2‑8 °C (refrigerated). Keep the vial in its original packaging, protect it from light, and avoid freezing or shaking the solution. Do not use the product if the solution appears discolored or contains particles.

The medication is given as an intravenous injection by a qualified healthcare professional. The infusion rate and total daily dose are determined by the prescriber, taking into account the patient’s clinical condition and renal function.

Serious adverse events include severe allergic reactions (anaphylaxis, angioedema), life‑threatening skin conditions such as Stevens‑Johnson syndrome, blood disorders like neutropenia or thrombocytopenia, and emergence of suicidal thoughts or behavior. Prompt medical attention is required if any of these occur.

Patients with a known hypersensitivity to levetiracetam or any component of the formulation should avoid the drug. Those with severe renal impairment must have dose adjustments; otherwise, use is contraindicated. Caution is also advised in individuals with a history of psychiatric disorders or suicidal ideation.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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