Product image of Levetiracetam Ethypharm (Levetiracetam) supplied by GNH India

Levetiracetam Ethypharm

Active Ingredient:
Levetiracetam
Origin:
EU

Levetiracetam Ethypharm (Levetiracetam)

Levetiracetam, the active ingredient in Levetiracetam Ethypharm, is a Anticonvulsant presented as a intravenous solution for intravenous use. It treats partial‑onset, generalized tonic‑clonic and myoclonic seizures in patients with epilepsy and is administered under medical supervision as part of standard epilepsy management protocols.

GNH India supplies Levetiracetam Ethypharm as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres, oncology centres, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory documentation for import and distribution.

Manufacturer / TM Owner

Altan Pharmaceuticals S.A.

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Indications & Clinical Uses

  • Levetiracetam is an antiepileptic drug used to control various seizure types.
  • Partial-onset seizures: reduces seizure frequency in patients with focal epilepsy.
  • Generalized tonic-clonic seizures: helps achieve seizure freedom in patients with primary generalized epilepsy.
  • Myoclonic seizures: diminishes myoclonic jerks and improves daily functioning in affected individuals.

How It Works

  • Levetiracetam binds to the synaptic vesicle protein SV2A, modulating neurotransmitter release and stabilizing neuronal membranes. This interaction reduces excessive neuronal firing and excitability, thereby preventing the propagation of epileptic discharges across the central nervous system.

Side Effects

Levetiracetam may cause a range of adverse reactions, most of which are mild to moderate.

Common Side Effects

  • Dizziness
  • Fatigue
  • Somnolence
  • Headache
  • Irritability
  • Nausea

Serious or Rare Side Effects

  • Severe allergic reactions (anaphylaxis, angioedema)
  • Stevens‑Johnson syndrome or toxic epidermal necrolysis
  • Blood dyscrasias (e.g., neutropenia, thrombocytopenia)
  • Suicidal thoughts or behavior
  • Severe skin rash
  • Respiratory depression (rare)

Precautions & Warnings

Before initiating therapy, clinicians should consider several safety factors.

  • Renal impairment: adjust dose based on creatinine clearance.
  • Hepatic impairment: monitor liver function tests.
  • Pregnancy: risk unknown; use only if benefits outweigh risks.
  • Known hypersensitivity: avoid administration.
  • Concomitant antiepileptics: monitor for additive CNS effects.
  • Store at ambient temperature: keep in original packaging, protect from moisture and light.

Avoid Interactions

Levetiracetam has a relatively low interaction profile, but certain drugs may affect its plasma levels.

Major Interactions (Avoid)

  • Carbamazepine: may reduce levetiracetam concentrations.
  • Phenobarbital: may lower levetiracetam exposure.

Moderate Interactions (Monitor Closely)

  • Phenytoin: modest reduction in levetiracetam levels.
  • Valproic acid: may increase risk of central nervous system depression.
  • Alcohol: can enhance sedation and dizziness.
  • Other antiepileptics: monitor for cumulative side‑effects.

Frequently Asked Questions

Levetiracetam Ethypharm is an intravenous antiepileptic medication indicated for the treatment of partial‑onset, generalized tonic‑clonic, and myoclonic seizures in patients with epilepsy. It helps reduce seizure frequency and severity when administered under medical supervision.

Levetiracetam binds to the synaptic vesicle protein SV2A, which modulates neurotransmitter release. This action stabilizes neuronal membranes and decreases excessive neuronal excitability, thereby preventing the spread of epileptic activity across the brain.

The dosage of levetiracetam is individualized by the prescribing clinician based on the patient’s age, weight, renal function, and seizure type. The prescriber determines the appropriate infusion rate and total daily amount according to clinical guidelines.

Safety data for levetiracetam in pregnancy and lactation are limited. It should only be used if the potential benefit to the mother outweighs any possible risk to the fetus or infant, and decisions are made in consultation with a healthcare professional.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed), and import documentation.

Levetiracetam has a distinct mechanism targeting SV2A and exhibits fewer drug‑enzyme interactions compared with many older antiepileptics such as carbamazepine or phenytoin. This profile often results in a more predictable pharmacokinetic behavior and may simplify combination therapy, though individual response varies.

Levetiracetam Ethypharm should be stored at ambient temperature, below 25 °C, in its original packaging to protect from moisture and light. Do not freeze the solution, and ensure the container remains sealed until use.

Levetiracetam Ethypharm is given intravenously by slow infusion under the supervision of qualified healthcare personnel. The infusion rate and total daily dose are determined by the prescribing physician based on the patient’s clinical condition.

Serious risks include severe allergic reactions such as anaphylaxis, life‑threatening skin conditions like Stevens‑Johnson syndrome, blood dyscrasias, and the emergence of suicidal thoughts or behaviors. Patients should be monitored closely for any of these events, especially during treatment initiation.

Levetiracetam is contraindicated in individuals with known hypersensitivity to levetiracetam or any of its excipients. Caution is also advised for patients with severe renal impairment who have not had dose adjustments, and for those with a history of serious psychiatric reactions.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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